- Shoulder Injury and Treatment
- Orthopaedic implants and arthroplasty
- Orthopedic Surgery and Rehabilitation
- Surgical Simulation and Training
- Immune Cell Function and Interaction
- Shoulder and Clavicle Injuries
- Cardiac, Anesthesia and Surgical Outcomes
- Bone fractures and treatments
- Trauma and Emergency Care Studies
- Hip and Femur Fractures
- COVID-19 and healthcare impacts
- Infection Control and Ventilation
- Diversity and Career in Medicine
- Blood transfusion and management
- Sarcoma Diagnosis and Treatment
- CAR-T cell therapy research
- Innovations in Medical Education
- Hip disorders and treatments
- Musculoskeletal pain and rehabilitation
- Anatomy and Medical Technology
- Orthopedic Infections and Treatments
- Streptococcal Infections and Treatments
- Bone and Joint Diseases
- Elbow and Forearm Trauma Treatment
- Foot and Ankle Surgery
Cambridge University Hospitals NHS Foundation Trust
2025
Whittington Health NHS Trust
2020-2024
University College London
2020-2024
Great Ormond Street Hospital
2024
Barts Health NHS Trust
2022-2024
Royal London Hospital
2022-2024
Institute of Child Health
2023
Barking, Havering And Redbridge University Hospitals NHS Trust
2021-2023
Queen's Hospital
2023
Great Ormond Street Hospital for Children NHS Foundation Trust
2023
Interleukin-15 (IL-15) is a cytokine that has been shown to expand CD8 T cell and natural killer (NK) populations, therefore potential for potentiating adoptive immune therapy cancer. Previously, IL-15 induce proliferation of memory cells through activation telomerase. Here, we investigated whether telomerase also activated during the mediated NK NKT-like (CD56+CD3+) cells. We examined extent each three signaling pathways known be stimulated by IL-2/IL-15 (JAK-STAT, PI3K-AKT Ras-RAF/MAPK)...
Improving psychological wellbeing in healthcare professionals has demonstrable links with improvements system-performance and patient outcomes. The aims of this study were to determine the prevalence burnout among orthopaedic surgeons within United Kingdom (UK) identify any influencing factors.
Objective The SABINA (SABA use IN Asthma) program was initiated to describe short-acting β2-agonists (SABA) prescription patterns and assess the impact of its over-prescription on exacerbation risk asthma control. We evaluated SABA in patients with Indian cohort III.Methods This multi-centre, observational, cross-sectional study included retrospective real-time electronic data collection. Data were extracted from medical records (aged >12 years) having >3 consultations same healthcare...
Glenoid bone loss represents a challenge in shoulder arthroplasty and often precludes standard implants. The CAD-CAM total replacement (TSR) is an option these cases. This study aimed to assess survivorship long-term patient outcomes of the TSR.
This study assesses whether sterile surgical helmet systems (SSHS) provide surgeons with additional protection from aerosol pathogens alongside their traditional role protecting against splash. There has been debate on to use such in reopening elective orthopaedic surgery during the current COVID-19 pandemic environment. Thirty-five participants were enrolled a double-blinded randomised controlled investigating efficacy of Stryker Flyte Surgical Helmet (Stryker Corporation, Kalamazoo, MI,...
Tranexamic acid (TXA), a synthetic antifibrinolytic drug, effectively reduces blood loss by inhibiting plasmin-induced fibrin breakdown. This is the first study in United Kingdom to investigate effectiveness of TXA surgical management isolated spine trauma.
Abstract Background Patients with osteonecrosis of the femoral head secondary to DDH frequently require total hip arthroplasty (THA), but it is not well understood which factors necessitate this requirement. We determined incidence THA in patients who have and associated need for THA. Methods included received closed or open reductions between 1995 2005 subsequent development osteonecrosis. according Bucholz Ogden; osteoarthritis severity (Kellgren-Lawrence), subluxation (Shenton’s line);...