A5038862540- Ultrasound and Hyperthermia Applications
- Ultrasound Imaging and Elastography
- Photoacoustic and Ultrasonic Imaging
- MRI in cancer diagnosis
- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Advanced MRI Techniques and Applications
- Ultrasound and Cavitation Phenomena
- Cardiovascular Health and Disease Prevention
- Hemodynamic Monitoring and Therapy
- AI in cancer detection
- Breast Lesions and Carcinomas
- Ultrasonics and Acoustic Wave Propagation
- Prostate Cancer Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Angiogenesis and VEGF in Cancer
- Renal cell carcinoma treatment
- Radiomics and Machine Learning in Medical Imaging
- Breast Cancer Treatment Studies
- Pancreatic and Hepatic Oncology Research
- Cardiovascular Function and Risk Factors
- Non-Invasive Vital Sign Monitoring
- Spectroscopy Techniques in Biomedical and Chemical Research
- Cerebrovascular and Carotid Artery Diseases
Thomas Jefferson University
2016-2025
Skåne University Hospital
2025
Lund University
2025
Thomas Jefferson University Hospital
2005-2024
Columbia College - South Carolina
2024
University of Southern California
2023-2024
Texas Children's Hospital
2018-2024
Baylor College of Medicine
2018-2024
Northeast Ohio Medical University
2019-2024
University of Alabama at Birmingham
2019-2024
Initially, a set of guidelines for the use ultrasound contrast agents was published in 2004 dealing only with liver applications. A second edition 2008 reflected changes available and updated liver, as well implementing some non-liver Time has moved on, need international on CEUS become apparent. The present document describes third iteration recommendations hepatic enhanced (CEUS) using specific imaging techniques. This joint WFUMB-EFSUMB initiative implicated experts from major leading...
Zero-thickness interface models are developed to describe the encapsulation of microbubble contrast agents. Two different rheological interface, Newtonian (viscous) and viscoelastic, with parameters such as surface tension, dilatational viscosity, elasticity presented characterize encapsulation. The applied a widely used based ultrasound agent. Attenuation passing through solution agent is measured. model for determined by matching linearized dynamics measured attenuation data. investigated...
The Nakagami distribution was proposed recently for modeling the echo from tissue. In vivo breast data collected patients with lesions were studied using this model. Chi-square tests showed that is a better fit to envelope than Rayleigh distribution. Two parameters, m (effective number) and /spl alpha/ cross section), associated used classification of masses. Data 52 masses/lesions in studies. Receiver operating characteristics calculated methods based on these two parameters. results...
Intravenously injected ultrasonic contrast agents making use of encapsulated gas microbubbles have excellent clinical potential for both color and spectral Doppler studies. However, a number artifacts are associated with sonographic agent measurements. Three were identified: (1) "blooming," (2) increased maximum shift, (3) "bubble noise." Experiments been conducted Albunex Levovist. These into rabbits humans to allow the cause be established. Color blooming occurs soon after bolus injection...
To study the use of power Doppler sonography for assessing changes in vascularity during treatment fracture sites with low-intensity ultrasound.In 6 dogs (3 pairs), subcutaneous dissection midshaft ulna allowed symmetrical osteotomies to be made a reciprocation saw. Three were treated and 3 used as controls. The site was subjected 1.5-MHz ultrasound (30 mW/cm2) 20 minutes daily from therapeutic ultrasonic device. Gray scale performed evaluate site. Power assess flow patterns at surrounding...
To evaluate the flow imaging capabilities of a new prototype ultrasound (US) image processing technique (superb micro-vascular [SMI]; Toshiba Medical Systems, Tokyo, Japan) for depiction microvascular in normal thyroid tissue and nodules compared with standard color power Doppler US imaging. Ten healthy volunteers 22 patients, total 25 nodules, scheduled US-guided fine needle aspiration were enrolled this prospective study. Subjects underwent examination consisting grayscale, (CDI PDI)...
PURPOSE: To determine if lymphatic channels and sentinel lymph nodes (SLNs) with without metastases can be detected ultrasonography (US) after peritumoral injection of a US contrast agent to used assess SLNs for the presence metastatic infiltration. MATERIALS AND METHODS: Six swine 17 melanomas were evaluated. Conventional gray-scale, color flow, gray-scale phase-inversion harmonic examinations performed. A was administered in four sites around each melanoma (1-mL total dose)....
The subharmonic emission from insonified contrast microbubbles was used to create a new imaging modality called Subharmonic Imaging. response of ultrasound pulses first investigated for determining adequate acoustic transmit parameters. A-lines and gray scale images were then obtained using laboratory pulse-echo system in vitro modified scanner vivo. Excellent suppression all backscattered signals other than achieved while further optimization is required vivo images.
A galactose-based sonographic contrast agent, which produces stable microbubbles capable of traversing the cardiopulmonary circulation, was used to enhance Doppler signals in blood vessels varying size after intravenous injection. series experiments using dogs, rabbits, and woodchucks conducted establish ability agent reflectivity normal tissue, tumor blood. Although no enhancement perceptible tissue on sonogram, significant color spectral demonstrated a variety vessels. These included...
Two nonlinear interfacial elasticity models—interfacial decreasing linearly and exponentially with area fraction—are developed for the encapsulation of contrast microbubbles. The strain softening (decreasing elasticity) results from association between constitutive molecules encapsulation. models are used to find characteristic properties (surface tension, elasticity, viscosity parameters) a commercial agent. Properties found using ultrasound attenuation measured through suspension Dynamics...
To compare subharmonic aided pressure estimation (SHAPE) with catheter-based measurements in human patients chronic liver disease undergoing transjugular biopsy.This HIPAA-compliant study had U.S. Food and Drug Administration institutional review board approval, written informed consent was obtained from all participants. Forty-five completed this between December 2010 2011. A clinical ultrasonography (US) scanner modified to obtain SHAPE data. After biopsy as part of the standard care, 45...
Our group has proposed the concept of subharmonic aided pressure estimation (SHAPE) utilizing microbubble-based ultrasound contrast agent signals for noninvasive hydrostatic blood pressures. An experimental system in vitro SHAPE was constructed based on two single-element transducers assembled confocally at a 60° angle to each other. Changes first, second and amplitudes five different agents were measured static pressures from 0–186 mmHg, acoustic 0.35–0.60 MPa peak-to-peak frequencies...