A5084969476- Tissue Engineering and Regenerative Medicine
- Reproductive Biology and Fertility
- Photodynamic Therapy Research Studies
- Extracellular vesicles in disease
- Telomeres, Telomerase, and Senescence
- Exercise and Physiological Responses
- Glioma Diagnosis and Treatment
- Lipid Membrane Structure and Behavior
- Glaucoma and retinal disorders
- Dietary Effects on Health
- Adipose Tissue and Metabolism
- Cellular transport and secretion
- Cancer Treatment and Pharmacology
- Lower Extremity Biomechanics and Pathologies
- Cerebral Venous Sinus Thrombosis
- Endoplasmic Reticulum Stress and Disease
- Ocular and Laser Science Research
Istanbul University-Cerrahpaşa
2023-2024
Glioblastoma tumors are the most aggressive primary brain that develop resistance to temozolomide (TMZ). Eribulin (ERB) exhibits a unique mechanism of action by inhibiting microtubule dynamics during G2/M cell cycle phase. We utilized T98G human glioma line investigate effects ERB and TMZ, both individually in combination. The experimental groups were established as follows: control, E5 (5 nM ERB), T0.75 (0.75 mM TMZ), T1 (1.0 combination (E5+T0.75 E5+T1). All showed significant decrease...
The steroidogenic activity of the granulosa cells is important for reproductive cycle, and lipoproteins are involved in this process. clathrin-mediated endocytosis pathway LDL transport considered to be main one eukaryotic cells. However, there no studies that elucidate internalization human clarifying whether endocytic functional aim study investigate role clathrin v-SNARE proteins formation vesicles In study, COV434 were cultured divided into four groups where some Dil-conjugated...
In the organ microenvironment stromal cells make up an essential population, however research on them has been very limited. The stroma mainly consists of fibroblasts that reside together with mesenchymal cells, endothelial pericytes, neurons, adipocytes, immune etc. different morphologies and functional properties have led to subclassification cell types in connective tissue. Among are interstitial Cajal telocytes. Telocytes one newer known for their small bodies long telopods recently...
Abstract Telocytes (TCs) are characterized by a small oval-shaped cell body with long prolongations that called telopods (Tps). PDGFR-β and c-kit markers may assist for the immunohistochemical identification of TCs; however, these means they cannot be identified absolute specificity. Transmission electron microscopy (TEM) is considered as gold standard method TCs observation. Studies on in female reproductive system limited, there lack awareness regarding rat ovaries. We aimed to demonstrate...