A5035092573- Molecular spectroscopy and chirality
- Chemical Synthesis and Analysis
- Advanced NMR Techniques and Applications
- Analytical Chemistry and Chromatography
- Carbohydrate Chemistry and Synthesis
- Advanced MRI Techniques and Applications
- Phytochemicals and Antioxidant Activities
- Metabolomics and Mass Spectrometry Studies
- Enzyme Structure and Function
- Glycosylation and Glycoproteins Research
- DNA and Nucleic Acid Chemistry
- Electron Spin Resonance Studies
- NMR spectroscopy and applications
- Metabolism and Genetic Disorders
- Biopolymer Synthesis and Applications
- Cancer, Hypoxia, and Metabolism
- Mass Spectrometry Techniques and Applications
- Amino Acid Enzymes and Metabolism
- Medical Imaging Techniques and Applications
- Lanthanide and Transition Metal Complexes
- Synthesis of Organic Compounds
- Microbial Natural Products and Biosynthesis
- Protein Structure and Dynamics
- Neonatal Respiratory Health Research
- Hemoglobin structure and function
University of Alabama at Birmingham
2024-2025
The University of Texas at El Paso
2024-2025
Wright Institute
2023
University of Florida
2020-2022
Florida College
2022
German Cancer Research Center
2004-2020
Heidelberg University
2004-2020
University of Utah
1984-2018
Rosetta Stone (United States)
2016
University of Washington
2016
The contents of secondary plant substances in solvent extracts various byproducts (barks, kernels, peels, and old young leaves) a range Brazilian mango cultivars were identified quantitated. results show that the profiles such as xanthone C-glycosides, gallotannins, benzophenones different vary greatly but are fairly consistent across cultivars. free radical scavenging activity was evaluated using high-performance liquid chromatography-based hypoxanthine/xanthine oxidase assay revealed...
Because olive oil is an important component of the Mediterranean diet, it necessary to establish unequivocal identification major potential antioxidant phenolic compounds contains.The antioxidants in extra virgin were isolated and purified. Structural analysis was conducted using several spectroscopic techniques, including mass spectrometry nuclear magnetic resonance (NMR). In particular, detailed (1)H (13)C NMR data are presented, assignment errors literature corrected.The show for first...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhosphorus-31 nuclear magnetic resonance study of alkaline phosphatase: the role inorganic phosphate in limiting enzyme turnover rate at pHWilliam E. Hull, S. Halford, H. Gutfreund, and Brian D. SykesCite this: Biochemistry 1976, 15, 7, 1547–1561Publication Date (Print):April 6, 1976Publication History Published online1 May 2002Published inissue 6 April...
Abnormalities have been previously noted in the lipid content of lavage fluid patients with bacterial pneumonia. In order to determine if these changes were also seen surfactant apoproteins, we studied levels protein A (SP-A) Patients without human immunodeficiency virus who being evaluated for pulmonary infiltrates underwent bronchoscopy bronchoalveolar (BAL). Twenty-two pneumonia, 12 caused by gram-positive organisms (Gm+ PNEU) and 10 gram-negative (Gm- PNEU), compared idiopathic fibrosis...
There are considerable differences between bacterial and mammalian glycans. In contrast to most eukaryotic carbohydrates, glycans often composed of repeating units with diverse functions ranging from structural reinforcement adhesion, colonization camouflage. Since typically displayed at the cell surface, they can interact environment and, therefore, have significant biomedical importance. The sequence characteristics (monosaccharide composition, modifications, linkage patterns) for higher...
The structure of carbohydrate units bronchial-mucus glycoproteins obtained from cystic fibrosis patients was investigated by 500-MHz 1H-NMR spectroscopy and methylation analysis. To that purpose, the much subjected to alkaline borohydride degradation. Neutral oligosaccharide-alditols, ranging in size disaccharides pentasaccharides, were isolated. Eight compounds could be purified homogeneity; furthermore, three fractions consisting mainly two components. For all 14 primary elucidated. found...
Cystic echinococcosis is a worldwide disease caused by larval stages of the parasite Echinococcus granulosus (canine tapeworm). In clinical practice, staging cyst development ultrasonography (US) has allowed treatment options to be tailored individual patient needs. However, empirical correlation between morphology and viability not always dependable has, until now, required confirmation invasive assessment content light microscopy (LM), for example. Alternatively, high-field 1H MRS may used...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFluorine-19 nuclear magnetic resonance study of fluorotyrosine alkaline phosphatase: the influence zinc on protein structure and a conformational change induced by phosphate bindingWilliam E. Hull Brian D. SykesCite this: Biochemistry 1976, 15, 7, 1535–1546Publication Date (Print):April 6, 1976Publication History Published online1 May 2002Published inissue 6 April...
Tumor necrosis factor-alpha (TNF-alpha) decreased the expression of pulmonary surfactant proteins SP-A and SP-B in human adenocarcinoma cell lines. The effect TNF alpha on content mRNA line, H441-4, was concentration time dependent. cellular to less than 10% control 48 h after addition. de novo synthesis accumulation media. within 12 addition alpha, with nearly complete loss observed 24 h. Inhibitory effects were dose-related inhibition caused by 25 ng/ml alpha. distinct from interferon...
The EUROCarbDB project is a design study for technical framework, which provides sophisticated, freely accessible, open-source informatics tools and databases to support glycobiology glycomic research. relational database containing glycan structures, their biological context and, when available, primary interpreted analytical data from high-performance liquid chromatography, mass spectrometry nuclear magnetic resonance experiments. Database content can be accessed via web-based user...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNature of species present in an aqueous solution potassium silicateR. K. Harris, C. T. G. Knight, and W. E. HullCite this: J. Am. Chem. Soc. 1981, 103, 6, 1577–1578Publication Date (Print):March 1, 1981Publication History Published online1 May 2002Published inissue 1 March 1981https://pubs.acs.org/doi/10.1021/ja00396a056https://doi.org/10.1021/ja00396a056research-articleACS PublicationsRequest reuse permissionsArticle...
A theoretical description of 19F–1H dipolar nuclear spin relaxation in multispin systems is presented which serves to explain the behavior 19F fluorine-labeled proteins when protons are not irradiated. The complete solution two-spin 1H–19F spin–lattice discussed for various experimental pulse techniques commonly employed Fourier transform NMR. Recovery curves following a single 90° applied containing several simulated by using digital computer calculate time development set differential...
Thermolysis of C120O at 550–600°C yielded a soluble product fraction containing C60, C119 and higher-mass species. Using two-step HPLC procedure two species, both with molecular weight corresponding to C119, were isolated in 3.5% 2% yield. The 125.76 MHz 13C-NMR spectrum the latter more stable obtained from 13C enriched samples proved that this species consists C58 cages bridged by three sp3 carbons, which are equivalent. NMR-consistent structures have been investigated modeling turned out...