A5059984111- Mosquito-borne diseases and control
- Respiratory Support and Mechanisms
- Respiratory viral infections research
- Neonatal Respiratory Health Research
- Immunotherapy and Immune Responses
- Toxin Mechanisms and Immunotoxins
- Viral Infections and Vectors
- Vector-borne infectious diseases
- T-cell and B-cell Immunology
Johns Hopkins Medicine
2020
Johns Hopkins University
2020
BACKGROUND AND OBJECTIVES Respiratory viral infections increase risk of asthma in infants and children. Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus can cause lung inflammation prolonged symptoms. We sought to determine whether SARS-CoV-2 infection modified pediatric incident risk. METHODS This retrospective cohort study examined children ages 1 16 within Children’s Hospital Philadelphia Care Network who received polymerase chain reaction (PCR)...
Abstract Objectives During the SARS-CoV-2 pandemic, new patient evaluations in pediatric rheumatology were performed using telehealth. Given workforce shortage, telehealth may be a way to efficiently triage referrals. The objective was assess utility of visits as diagnostic tool accurately need for in-person evaluation. Methods This retrospective cohort study patients evaluated by visit from March 1 June 30, 2020 at tertiary center. Electronic health record documentation subsequent...
The Aedes aegypti mosquito transmits both dengue virus (DENV) and Zika (ZIKV) . Individuals in endemic areas are at risk for infection with viruses, as well repeated DENV infection. In the presence of anti-DENV antibodies, outcomes secondary range from mild to life threatening. Furthermore, role cross-reactive antibodies on course ZIKV remains unclear. We assessed ability mAbs or polyclonal immunoglobulin isolated after vaccination upregulate type I IFN production by plasmacytoid DCs (pDCs)...