Rajeev Kumar

ORCID: 0000-0003-2259-8341
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Research Areas
  • Cancer, Hypoxia, and Metabolism
  • Cancer Cells and Metastasis
  • Head and Neck Cancer Studies
  • Effects of Environmental Stressors on Livestock
  • RNA modifications and cancer
  • Protein Degradation and Inhibitors
  • Cell Adhesion Molecules Research
  • Pesticide Exposure and Toxicity
  • Cancer, Stress, Anesthesia, and Immune Response
  • Pesticide and Herbicide Environmental Studies
  • Esophageal Cancer Research and Treatment
  • Genetic factors in colorectal cancer
  • Potassium and Related Disorders
  • Lymphatic System and Diseases
  • Veterinary Oncology Research
  • Oral health in cancer treatment
  • Congenital gastrointestinal and neural anomalies
  • Congenital Ear and Nasal Anomalies
  • Folate and B Vitamins Research
  • Genital Health and Disease
  • Cancer-related Molecular Pathways
  • Mercury impact and mitigation studies
  • Sexual function and dysfunction studies
  • CAR-T cell therapy research
  • Heavy Metal Exposure and Toxicity

National Institute of Cancer Prevention and Research
2024

All India Institute of Medical Sciences
2022

Silchar Medical College and Hospital
2018-2020

Children's Hospital of Pittsburgh
2019

Background: Esophageal squamous cell carcinoma (ESCC) is a common cancer in the north east of India. The present study concerned prevalence human papilloma virus (HPV) ESCC eastern India and its impact on response to chemotherapy. Materials Methods: p16 expression, surrogate marker for HPV infection was assessed 101 pre-treatment biopsies locally advanced ESCC, reported from comprehensive centre India, using immunohistochemistry. All patients received neo-adjuvant Response clinically...

10.7314/apjcp.2015.16.16.7161 article EN cc-by Asian Pacific Journal of Cancer Prevention 2015-11-04

Aim: To evaluate the expression pattern of ALDH1 (aldehyde dehydrogenase 1), E-cadherin, Vimentin and Twist in early late onset sporadic colorectal cancer (CRC) to study association their with occurrence CRC at a young age. Materials & methods: Immunohistochemistry ALDH1, was performed on 103 pretreated biopsy samples. Results: found have strong correlation (p < 0.0001). Conclusion: High correlates CRC. over-expression poor overall survival colon cancer.

10.2217/bmm-2020-0206 article EN Biomarkers in Medicine 2020-10-01

Southeast Asia, especially India, is well known for the highest use of smokeless tobacco. These products are to induce oral squamous cell carcinoma. However, not all long-term tobacco-chewers develop In addition, germline variants play a crucial role in susceptibility, prognosis, development, and progression disease. prompted us study genetic susceptibility carcinoma among tobacco-chewers. Here, we presented retrospective on prolonged Northeast India identify potential protective or...

10.1177/1010428318793023 article EN cc-by-nc Tumor Biology 2018-08-01

Our study aims to analyse and compare the efficacy, adverse effect profile survival among Paclitaxel/Cisplatin/5-Flurouracil (TPF) induction chemotherapy Paclitaxel/carboplatin (PC) first line or cisplatin in a high-volume tertiary care cancer centre.

10.4103/jcrt.jcrt_2179_22 article EN Journal of Cancer Research and Therapeutics 2024-01-22

You have accessJournal of Urology1 Apr 2009LONG-TERM RESULTS OF A MODIFIED ESSED-SCHROEDER TECHNIQUE: SURGICAL CORRECTION PEYRONIE'S DISEASE ASSOCIATED WITH SEVERE DORSAL CURVATURE Bryan Bruner, Rajeev Kumar, Santosh Ernest F McPhail, and Ajay Nehra BrunerBryan Bruner More articles by this author , KumarRajeev Kumar KumarSantosh McPhailErnest McPhail NehraAjay View All Author Informationhttps://doi.org/10.1016/S0022-5347(09)60583-8AboutPDF ToolsAdd to favoritesDownload CitationsTrack...

10.1016/s0022-5347(09)60583-8 article EN The Journal of Urology 2009-03-14

Abstract Background: Worldwide there is an increase in the trend of early onset colorectal carcinoma individuals who are less than 45 years age. The composition young age cases ranges from 35% to 40% India. Currently, we do not have access any molecular marker that could predict disease and its clinical course. Aldehyde dehydrogenase 1 (ALDH1), Twist, E Cadherin Vimentin markers for cancer stem cells epithelial mesenchymal transition. However, paucity data on their significance terms impact...

10.1158/1538-7445.am2019-4924 article EN Cancer Research 2019-07-01

Ependymomas are the third most common pediatric brain tumor. Nine ependymoma subgroups have been described based on tumor location and genetics. Of supratentorial ependymomas, C11orf95-RELA fusion (ST-EPN-RELA) subgroup is aggressive. The RELA encoded protein an NF-κB transcription factor family member activates signaling. It has reported that other pathways important for ST-EPN-RELA tumors. We therefore hypothesized cells may be sensitive to signaling cascade inhibitors. To test our...

10.1093/neuonc/noz036.068 article EN Neuro-Oncology 2019-04-01
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