A5100339684- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Bone health and osteoporosis research
- Nutrition and Health in Aging
- Dermatology and Skin Diseases
- Hip and Femur Fractures
- Health and Wellbeing Research
- Nutrition, Health and Food Behavior
- Asthma and respiratory diseases
- Cervical and Thoracic Myelopathy
- Medical Imaging and Analysis
- Scoliosis diagnosis and treatment
- Infectious Diseases and Tuberculosis
- Tuberculosis Research and Epidemiology
- Esophageal and GI Pathology
- Diverse Approaches in Healthcare and Education Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pharmaceutical Practices and Patient Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Rheumatoid Arthritis Research and Therapies
- Organic Food and Agriculture
- Body Contouring and Surgery
- Acute Kidney Injury Research
- Acne and Rosacea Treatments and Effects
- COVID-19 Impact on Reproduction
Korea University
2014-2025
Ansan University
2022-2024
The University of Texas Health Science Center at San Antonio
2024
Seoul National University Hospital
2019-2024
Dunsan Korean Medicine Hospital
2024
Kyung Hee University
2024
Pukyong National University
2023
Seoul National University Bundang Hospital
2019-2022
Samsung Medical Center
2022
Sungkyunkwan University
2022
Recent studies have suggested a role for an altered intestinal microbiota in the pathophysiology of irritable bowel syndrome (IBS). However, no consensus has been reached regarding association between specific enteric bacterial groups and IBS. The aim this study was to investigate fecal mucosal-associated using two independent techniques samples from diarrhea-predominant IBS (D-IBS) healthy controls.Fecal colonic mucosal biopsy were obtained 10 D-IBS patients controls. Colonic tissue...
Dementia is a major concern among growing chronic diseases in the aging society and its association with polypharmacy has not been adequately assessed. The objective of this study was to determine between dementia through multiple statistical approaches. We conducted nested case-control for newly diagnosed cases using South Korean National Health Insurance Service sample cohort database (2002–2013, n = 1,025,340). Interactions (an average use ≥5 prescription drugs daily) comorbidities or...
Researchers have suggested models to predict the risk of postoperative AKI (PO-AKI), but an externally validated index that can be practically implemented before patients undergo noncardiac surgery is needed.We performed a retrospective observational study without preexisting renal failure who underwent operation (≥1 hour) at two tertiary hospitals in Korea. We fitted proportional odds model for ordinal outcome consisting three categories: critical (defined as Kidney Disease Improving Global...
Few studies directly comparing minimally invasive (MI) transforaminal lumbar interbody fusion (TLIF) and open TLIF offering long-term follow-up data have been performed to date. Therefore, we sought compare mid- outcomes between these two surgical approaches.This was a retrospective analysis of groups. We analyzed the details 97 patients with degenerative disease who were treated MI (n = 55) or 42) 2011-2014 had at least seven years available. Peri- postoperative compared. To evaluate rates...
Abstract Underweight is an important modifiable risk factor for fractures. However, there have been few large cohort studies regarding the relationship between underweight and fracture in general population. We investigated of development according to severity a population cohort. This nationwide study included 2,896,320 people aged ≥ 40 years who underwent national health checkups 2009 were followed up identify incidence until December 31, 2018. After applying exclusion criteria that...
We aimed to investigate how underweight affects the incidence of fractures, as well influence cumulative, longitudinal periods low body mass index (BMI) and changes in weight on fracture development. Data adults aged 40-year over who had three health screenings between January 1, 2007, December 31, 2009 were used determine new fractures. The hazard ratios (HRs) for fractures depending BMI, total cumulative number underweight, change time calculated using Cox proportional analysis. In this...
Low body weight is associated with an increased risk of fractures. However, the effect temporal changes in low status on fracture remains unknown. This study aimed to evaluate relationships between and fractures adults over age 40 years.This included data years old who underwent two biannual consecutive general health examinations January 1, 2007 December 31, 2009 extracted from National Health Insurance Database, a large nationwide population database. Fracture cases this cohort were...
Objectives The purpose of this study was to reconfirm the association between risk fracture and proton pump inhibitor use establish evidence for defining a high-risk group patients among users. Methods A nested case-control performed using data from National Health Insurance Sharing Service database period January 2007 December 2017. population included elderly women aged ≥65 years with claims peptic ulcer or gastro-esophageal reflux disease. cases were all incidental osteoporotic fractures,...
Pyogenic spondylitis is a condition with low incidence that can lead to neurological sequelae and even life-threatening conditions. While conservative methods, including antibiotics bracing, are considered the first-line treatment option for pyogenic spondylitis, it important identify patients who require early surgical intervention prevent progressive neurologic deficits or deterioration of systemic condition. Surgical should be in deteriorating However, currently, there lack guidelines,...
Ardisia tinctoria (AT) is a plant of the Myrsinaceae family. No studies on its anti-inflammatory effects have yet been reported. This study investigated activity AT. A non-cytotoxic methanol extract AT inhibited expression inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2), leading to significantly reduced levels nitric oxide (NO) prostaglandin E2 (PGE2) two proteins regulated by these, interleukin-1β (IL-1β) IL-6, in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophage cells. The...
A CaO-SiO2-P2O5-B2O3 bioactive glass-ceramic (BGS-7) spacer provides high mechanical stability, produces a chemical bond to the adjacent endplate, and facilitates fusion after spine surgery. This prospective, randomized, single-blind, non-inferiority trial aimed evaluate radiographic outcomes clinical efficacy of anterior cervical discectomy (ACDF) using BGS-7 for treating degenerative disorders. Thirty-six patients underwent ACDF (Group N), 40 polyetheretherketone (PEEK) cages filled with...
Background: Asthma and chronic obstructive pulmonary disease (COPD) both require long-term management, patients with asthma-COPD overlap (ACO) need comprehensive prolonged care beyond pharmacotherapy. However, due to limited research on ACO, treatment strategies outcomes remain unclear. This highlights the for further multidisciplinary improve ACO prognosis.Case Presentation: case report describes a patient who presented symptoms of cough, sputum, wheezing, dyspnea, oral dryness. The was...
Changes in the thoracolumbar angle (TLA) would play a pivotal role reciprocal changes following spine realignment surgery, thereby leading to development of proximal junctional kyphosis (PJK). This study aimed investigate association between TLA and PJK adult spinal deformity surgery.A total 107 patients were divided into PJK+ PJK- groups according within 12 months after surgery. The spinopelvic radiological parameters compared groups. A multivariate logistic regression model was used...
Background: Korean type 2 diabetic patients are known to differ from western diabetes because of their unique characteristics, such as non-obese but centrally obese anthropometry and relatively more insulin secretory defects than resistance compared patients. Methods:We recruited 1,646 in the present study excluded 45 with fasting C-peptide < 0.20 nmol/L.We had assessed secretion by serum level short tolerance test (Kitt ; rate constant for plasma glucose disappearance, %/min) private...
A retrospective observational study The purpose of this was to characterize the learning curve for a single level unilateral laminectomy and bilateral decompression in lumbar spinal stenosis using cumulative summation test. Unilateral proposes potential benefit with minimizing surgery-related instability compared traditional laminectomy, by preserving posterior stabilizing structures contralateral facet joint neural arch. Due narrow surgical corridor, it is considered exhibit steep as other...
Being underweight is associated with a high risk of hip fracture. However, the impact change in status on fracture unknown. This study performed to investigate relationship between and included 1,713,225 subjects aged ≥40 years who underwent two consecutive national health screenings 2007 2009. We prospectively assessed 2010 2018 according changes status. divided participants into four groups status: consistent non-underweight (non-underweight non-underweight), became (underweight...