A5052389517- Cardiovascular Conditions and Treatments
- Meat and Animal Product Quality
- Cardiac electrophysiology and arrhythmias
- Nutrition and Health Studies
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac Fibrosis and Remodeling
- Congenital heart defects research
- Veterinary Oncology Research
- Cardiovascular Function and Risk Factors
- Veterinary Equine Medical Research
- Pulmonary Hypertension Research and Treatments
- Pharmacological Effects and Assays
- Veterinary Medicine and Surgery
- Cardiovascular Effects of Exercise
- Congenital Heart Disease Studies
- Reproductive Physiology in Livestock
- Animal health and immunology
- Adipose Tissue and Metabolism
- Cardiovascular Disease and Adiposity
- Heart Rate Variability and Autonomic Control
- Cardiac Ischemia and Reperfusion
- Cardiac Imaging and Diagnostics
- Cardiac tumors and thrombi
- Genetic and phenotypic traits in livestock
Nicolaus Copernicus University
2019-2025
Wroclaw University of Environmental and Life Sciences
2014-2024
Wroclaw Research Centre EIT+ (Poland)
2010-2024
National Veterinary Research Institute
2020
Military Hospital
2017
Wroclaw Medical University
2017
Instytut Środowiska Rolniczego i Leśnego Polskiej Akademii Nauk
1995-2006
University of Wrocław
2004
University of Agriculture in Krakow
1998
Myocarditis is a disease caused by numerous etiological factors and characterized non-specific course. The only method allowing for precise characterization of inflammatory changes the histopathological examination heart muscle specimens. study was conducted on preparations from 11 dogs with ante-mortem diagnosis cardiac disease. Animals presented poor response to an applied treatment or had suspected sudden death. specimens were taken post-mortem, preserved stained haematoxylin eosin....
The prevalence of arrhythmias in dogs and the influence sex, breed, age, body weight were analysed over a seven-year span.In total, 1189 referrals for cardiological examination by electrocardiography received at one academic centre Poland between 2008 2014. largest proportion examined cross-breeds with below 25 kg (n = 153, 12.87%), followed German Shepherds 122, 10.26%), Labrador Retrievers 68, 5.72%), Yorkshire Terriers 63, 5.3%), Boxers 60, 5.05%). Retrospective analysis was made 1201...
Excessive consumption of food rich in saturated fatty acids and carbohydrates can lead to metabolic disturbances cardiovascular disease. Hyperlipidemia is a significant risk factor for acute cardiac events due its association with oxidative stress. This leads arterial wall remodeling, including an increase the thickness intima media complex (IMT), endothelial dysfunction leading plaque formation. The decreased nitric oxide synthesis accumulation lipids result reduction vasodilating potential...
In veterinary practice, prostatic gland disorders are the most common diseases of reproductive system in males. The article discusses various dogs, focusing on cysts. It indicates that frequently occurring benign hyperplasia and inflammation, while cysts account for about 5% cases. Diagnosis involves clinical examination, ultrasound radiographic examination. Treatment can be pharmacological, including chemical castration, or surgical, marsupialization omentalization. this paper, authors...
Swine are recognized animal models of human cardiovascular diseases. Normal values cardiac morphology and function have been published for swine but smaller number pigs not whose weights ranged up 100 kg. In order to improve the value results an investigation on in when such data extrapolated humans, aim this study was document electrocardiographic echocardiographic measures swine. The comprised 170 single repeated measurements that were made 132 healthy domestic (Sus domesticus) between...
Abstract Background There are limited options to diagnose acute kidney injury (AKI) in horses. Symmetric dimethylarginine (SDMA) is routinely used human and small animal medicine. The aim of this study was assess serum SDMA concentrations healthy horses with AKI. objective evaluate the association of: 1) age, 2) sex, 3) body weight 4) creatinine urea levels on concentrations. Fifty-three horses, including 17 foals (2–6 months age) 36 adult (3–29 years age), 23 AKI were included based...
In the period of 3 years, 9 tumours chemodectoma were supravitally diagnosed and histopathologically verified in dogs. this 15 351 dogs admitted to Clinic Dogs Cats 2 145 examined cardiological outpatient clinic for This tumour is located a typical place - at base heart. Most frequently manifested older boxers. Only one case such was another breed The ranged size between 16 cm diameter. principal sign accompanying cardiac involved dyspnoea but cases yielded no clinical signs. All diagnoses...
Dysfunction of heart leads inevitable to the dysfunction kidney which is termed as cardiorenal syndrome (CRS). Previous studies have confirmed existence CRS in dogs with degenerative mitral valve disease (DMVD). The goal study was assess usefulness commercial test measure podocyturia and urine podocine/creatinine ratio (UPoC) an early marker injury. Urine calculated because numbers podocytes dependent on concentration. Fifty divided into three groups: fifteen healthy (control group), twenty...
Introduction: Myxomatous mitral valve disease (MMVD) in dogs inevitably causes renal dysfunction. These interactions are known as the cardiorenal syndrome (CRS). The main aims of study were to evaluate whether resistive index (RRI) may be useful a non-invasive marker subclinical stage kidney injury with MMVD and compare RRI SDMA Cyst C. Methods: Forty-four divided into two groups: control—15 healthy heart group—29 (ACVIM class Cc). Study protocol included: anamnesis, clinical examination,...
Matrix metalloproteinases (MMPs) are involved in the remodeling of extracellular matrix various tissues. Their functioning could be related to formation complexes, containing MMP9, MMP2, tissue inhibitor type 1 (TIMP1), and neutrophil gelatinase-associated lipocalin (NGAL). Such complexes have not been investigated either myocardial or skeletal muscles. We examined 20 male pigs with heart failure (HF), 5 sham-operated animals. There were no differences mRNA expression TIMP1, NGAL between...
The impact of physical activity on carcinogenesis has been demonstrated in many studies. Taking into account the discrepant results exercise cell proliferation and apoptosis breast cancer, we aimed to examine training N-methyl- N-nitrosourea-(MNU)-induced mammary carcinogenesis. Fifty female rats were divided four groups according intensity they undertook. number developed tumors, tumor volume, histopathological diagnoses noted. Apoptosis studied by TUNEL-positive Ki-67-expressing cells. We...
Dilated cardiomyopathy (DCM) and chronic mitral valve disease (CMVD) in dogs are associated with heart chamber enlargement, also of the left atrium. DCM is often accompanied by rhythm disturbances (mainly atrial fibrillation or ventricular arrhythmias). In CMVD, arrhythmias observed less frequently. It still unclear whether enlargement these diseases results from volume overload if it connected other factors (e.g. disturbances). This study was conducted on myocardial specimens 31 dogs,...
Pulmonary venous hypertension (PVH) is caused by deteriorating left ventricular function. The most common cause of PVH in dogs myxomatous mitral valve degeneration (MMVD). It causes volume overload and an increase atrial pulmonary pressure (PVH), which leads to vascular wall remodeling contributes the perpetuation worsening PVH. also characteristic arterial (PAH). However, changes arise secondary heart failure progresses as disease progresses. On other hand, PAH a primary that can be...
Summary Heme oxygenase-1 (HO-1) decreases apoptosis, inflammation and oxidative stress. The aim of the study was to investigate effects intracoronary infusion allogenic bone marrow cells (BMC) overexpressing HO-1 in porcine model myocardial infarction (MI). MI produced by balloon occlusion a coronary artery. BMC were transduced with adenoviruses encoding for (HO-1 BMC) or GFP (GFP-BMC) genes. Prior reperfusion animals received BMC, control (unmodified GFP-BMC) placebo. Left ventricular (LV)...
Whereas interspecies variation in pharmacokinetics is a commonly investigated issue, variations drug kinetics within species are less documented. The aim of the study was to assess influence age-related changes haemodynamics on metronidazole (MTZ) and its hydroxy metabolite (MTZ-OH) turkeys. MTZ administered intravenously orally at dose 25 mg/kg. Plasma concentrations were assessed by high-performance liquid chromatography, pharmacokinetic parameters calculated noncompartmental analysis....
The global epidemic of cardiovascular diseases leads to increased morbidity and mortality caused mainly by myocardial infarction stroke. Atherosclerosis is the major pathological process behind this epidemic. We designed a novel model atherosclerosis in swine. Briefly, first group (11 pigs) received normal pig feed (balanced diet group—BDG) for 12 months, second (9 was fed Western high-calorie (unbalanced group—UDG) third (8 type 9 months later replaced 3 (regression group—RG). Clinical...
Quadricuspid aortic valve (QAV) and ventricular septal defect (VSD) are congenital heart defects have been described in both human veterinary medical literature. A 5-year-old half-bred bay stallion was referred for surgical castration. Cardiac murmurs were heard on the presurgical clinical examination cardiac revealed subcutaneous oedema, tachycardia with a precodrial thrill grade 5/6 pansystolic murmur, which auscultation of right left side chest. Examination B-mode echocardiograms presence...
Abstract Background Acute kidney injury (AKI) in horses may develop as a complication of primary disease or following the administration nephrotoxic drugs, and pose diagnostic challenge. Hence, main objective this study was to evaluate concentrations significance serum symmetric dimethylarginine (SDMA) conventional renal dysfunction biomarkers healthy horses, at risk developing AKI, with clinically evident AKI. A second aim assess how gastrointestinal exposure potentially drugs affected SDMA...
P-wave dispersion (Pd) is a new ECG index used in human cardiology and veterinary medicine. It defined as the difference between maximum minimum duration recorded from multiple different leads. So far no studies were performed assessing importance of dogs.The current study was aimed at determining proper value Pd healthy dogs (group I), with chronic valvular disease II) disturbances supraventricular conduction III). The tests carried out 53 dogs, 23 12 various breeds, sexes body weight 1,5...
1. The aim of this study was to determine if the pharmacokinetics (PK) florfenicol (FF) undergo age-dependent changes in broilers. Since drug elimination depends on cardiovascular functions, a haemodynamic performed parallel. 2. Broilers 0.68, 1.27, 2.45 and 5.13 kg were administered FF single intravenous dose 30 mg/kg body weight. Plasma concentrations determined using high-performance liquid chromatography PK parameters calculated non-compartmental model. Echocardiography used measure...
Abstract The aim of the study was to estimate prevalence tricuspid dysplasia (TD) in dogs with respect breed, age, sex, clinical signs, and echocardiographic findings compare this data literature. TD found 15 (6.5% congenital cardiac disease) 215 heart defects. All had right enlargement on thoracic radiographs, echocardiography, electrocardiography. Doppler echocardiography revealed valve regurgitation. Seven presented no symptoms date. took form Ebstein anomaly all Labrador Retrievers, one...