ABSTRACT Introduction A recent pan‐cancer transcriptome analysis indicated differential activity of alternative promoters genes TNS3 and LRRFIP1 in head neck squamous cell carcinoma compared to non‐cancerous tissue. The upregulated regulate expression transcripts TNS3‐203 LRRFIP1‐211. Objective Our aim was investigate the biomarker potential LRRFIP1‐211 oral cancer, most common type cancer. Materials Methods An silico approach used characterize interest. Relative evaluated by qRT‐PCR a group...

Background: It has been suggested that the word euthanasia should be abandoned because widespread imprecise use of "euthanasia" deprived it its precise meaning.Methods: On basis primary necessary condition for -that in interests one who will die -we examine and meaning expression.Discussion: We demonstrate above suggestions rely upon flagrant misuse or inappropriate word.The attention reader is drawn to morally problematic consequences expression argument abandoning term would justified...

It is generally claimed that there exist exceptional circumstances when taking human life may be approved and such actions justified on moral grounds. Precise guidelines in the medical field for making decisions concerning patients who are terminally ill or have irreparable injuries incompatible with a bearable life, difficult to establish. Recommendations take particular logical form of rule, as "in dubio pro vita", "when doubt favour life") been suggested some countries incorporated into...

The generalized traveling current source return stroke model (GTCS), Cvetic and Stanic [1995] is extended to take into account reflections occurring at ground the upper end of lightning channel, as well attenuation along channel. reflection factor top pulses are taken from TCS model, Heidler [2007]. Current sources placed activated length represented by channel discharge function introduced in GTCS model. Multiple give rise waves moving up down total composed according original reflected...

Some open access journals are believed to have devaluated the highly respected image of scientific journal. This has been, it is claimed, verified. Yet project we believe failed and show why think that failed. The study itself was badly conducted report, which Science published, a perfect example "bad science". If article published in were be taken as one "test" articles victim journal (a control though), would opposite what author concluded his paper: 100% controls (normal non-open...

A new form of the space charge distribution inside channel corona sheath that represents a generalization previously adopted or calculated densities is numerically analyzed. On one hand, use appropriate parameter values produces established as special cases this generalized distribution. other influence on dynamics can be examined. The simulations showed function possesses excellent features regarding flexibility in modeling different Besides, it proved to simple and easy calculate. Although...

This study proposes a reconfigurable open architecture control system for the Computer Numerical Control (CNC) woodworking educational machine tool called "EMCO F1 CNC". On this physical hardware reconfiguration (spindle position can be vertical and horizontal) is possible. The idea was to develop that would follow configuration changes of tool. character its reconfigurability demand possibilities machining programme simulations in order determine optimal workpiece workspace verification....

The generalized lightning traveling current source return stroke model (also called GTCS model) represents generalization of all engineering models that is the transmission line (TL models, also propagation models) and (TCS known as generation models). channel discharge function was introduced calculated for special cases within model. We applied new numerical method calculation function. proposed highly accurate, extremely efficient relatively simple.

Theory of Mind (ToM) is a social-cognitive ability to understand the mental states others. ToM functions are compromised in case disorders characterized by cognitive impairments. The Faux Pas Recognition test (FPRT) considered good measure verbal aspects as it measures social adaptation through adequate interpretation potentially sensitive and awkward situations. However, data on FPRT psychometric properties somewhat limited. aim present study evaluation Serbian population. adapted version...

Belgrade resembles a salon where you can see the most diverse styles and directions of architecture, old part city was greatly influenced by Russian architects. In dramatic period after First World War, more than 50,000 refugees from Imperial Russia arrived in Kingdom Serbs, Croats, Slovenes. They lived mainly their associations with special church school system. Among people who came to country many highly educated development all areas cultural social life Serbia. significantly improved...

Background/Aim. Aging entails a wide range of cognitive processes that are not independent one another. It leads to changes in physical-motor characteristics and sometimes disability. The aim this study was examine the association between multiple performances elderly subjects their abilities. Method. included 98 participants (60+) (16 males 82 females). Cognitive abilities were assessed by Montreal Assessment (MoCA)/Serbian version, physical measures Senior Fitness Test with its five...

Scientific publishing is a highly responsible enterprise that involves shared responsibilities between the authors and publisher. It based on mutual trust principles of respect freedom expression ideas. The author for content article truthfulness affirmations while publisher verifies formal coherency articles seldom engaged in verification original content. Publishing bad science damaging to scientific community society as whole. has been shown there are journals publish without much control...

Appearance of an overcompensated positive electric field in most vertical measurements performed very close to the channel core is explained using extended generalized traveling current source (extended GTCS) return stroke model with reflections from ground. New effects corona sheath due reflection pulses have been noted and taken into account. The channel-base separated two components. first component fast a greater peak value, while second slower lower peak. We've analyzed for which...