A5016111742- Mosquito-borne diseases and control
- Malaria Research and Control
- Insect symbiosis and bacterial influences
- Evolution and Genetic Dynamics
- Physiological and biochemical adaptations
- Mathematical and Theoretical Epidemiology and Ecology Models
Max Planck Institute for Infection Biology
2017-2023
Kiel University
2015
Malaria is a fatal human parasitic disease transmitted by mosquito vector. Although the evolution of within-host malaria virulence has been focus many theoretical and empirical studies, vector's contribution to this process not well understood. Here, we explore how within-vector resource exploitation would impact Plasmodium virulence. By combining dynamics epidemiology, develop mathematical model, which predicts that non-competitive restricts parasite To validate our experimentally...
Host-parasite coevolution is predicted to result in changes the virulence of parasite order maximise its reproductive success and transmission potential, either via direct host-to-host transfer or through environment. The majority experiments, however, do not allow for environmental persistence long lived stages, spite fact that these may be critical evolutionary spore forming parasites under natural conditions. We carried out a experiment using red flour beetle, Tribolium castaneum,...
Abstract Malaria is a fatal human parasitic disease transmitted by mosquito vector. The evolution of within-host malaria virulence has been the focus many empirical and theoretical studies. However, vector’s contribution to not well understood. Here we explored how within-vector resource exploitation impacts evolutionary trajectories Plasmodium virulence. We developed nested model dynamics epidemiology, which predicted that non-competitive restricts parasite To validate our model,...
Abstract Mosquitoes are vectors of human life-threatening pathogens, posing a significant global health threat. While the influence temperature on mosquito life-history traits has been extensively studied in laboratory settings, ecological factors shaping development and population dynamics natural environments remain poorly understood. Here, we used multi-disciplinary approach, integrating field data from Mali, experiments, mathematical modeling, to investigate causal relationships between...