A5028836353- Epilepsy research and treatment
- Psychosomatic Disorders and Their Treatments
- Mental Health and Psychiatry
- Cerebrovascular and genetic disorders
- Moyamoya disease diagnosis and treatment
- Peripheral Neuropathies and Disorders
- Neurological and metabolic disorders
- Intracranial Aneurysms: Treatment and Complications
- Neurology and Historical Studies
- Metalloenzymes and iron-sulfur proteins
- Pharmaceutical studies and practices
- Organ Donation and Transplantation
- Genetic Neurodegenerative Diseases
- Schizophrenia research and treatment
- Neurological diseases and metabolism
- Autoimmune Neurological Disorders and Treatments
- Migraine and Headache Studies
- Long-Term Effects of COVID-19
- Drug-Induced Ocular Toxicity
- Mitochondrial Function and Pathology
- Trigeminal Neuralgia and Treatments
- Hereditary Neurological Disorders
- Lipoproteins and Cardiovascular Health
- SARS-CoV-2 and COVID-19 Research
- History of Medical Practice
University of Glasgow
2003-2021
Queen Elizabeth University Hospital
2016-2020
Apollo Hospitals
2015
Southern General Hospital
2004-2014
Institute of Neurological Sciences
2003-2013
Neurosciences Institute
2005
Office of the Registrar General & Census Commissioner
2005
University Hospital of Wales
2003
Glasgow Life
2003
Abstract Emerging reports of rare neurological complications associated with COVID-19 infection and vaccinations are leading to regulatory, clinical public health concerns. We undertook a self-controlled case series study investigate hospital admissions from in the 28 days after first dose ChAdOx1nCoV-19 ( n = 20,417,752) or BNT162b2 12,134,782), SARS-CoV-2-positive test 2,005,280). There was an increased risk Guillain–Barré syndrome (incidence rate ratio (IRR), 2.90; 95% confidence interval...
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is caused by mutations of the Notch3 gene on 19p13. Varying phenotypic expression leads to under recognition misdiagnosis. Prevalence therefore remains uncertain. We sought estimate prevalence CADASIL in west Scotland.A register for was established at a regional neurosciences centre 2002. All patients genetically (exons 3, 4, 5, 6) or histologically confirmed residing two defined...
CADASIL is a monogenic small vessel vasculopathy causing recurrent stroke. Early descriptions suggested dementia and disability were common from the 5th decade but there evidence of marked phenotypic variability. We investigated prevalence clinical features in west Scotland.We undertook retrospective review records patients with confirmed identified through specialist clinic. Patients divided to examine effect date diagnosis on outcomes characteristics at different ages. The location...
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) has typical clinical features that include stroke, migraine, mood disturbances cognitive decline. However, misdiagnosis is common. We hypothesized family history poorly elicited in individuals presenting of CADASIL enquiry into all four cardinal manifestations superior to elicitation premature stroke alone raising the diagnostic possibility CADASIL.Retrospective review histories at...
Multidetector computed tomography angiography (MDCTA) is a minimally invasive radiological technique providing high-resolution images of the arterial wall and angiographic lumen. We studied features vertebral artery dissection (VAD) in consecutive series patients investigated for acute stroke subarachnoid hemorrhage (SAH) order to confirm define diagnostic VAD on MDCTA.Review identified prospectively over 4-year period with assessed by MDCTA was conducted. Radiological were reanalyzed...
A 43‐year‐old lady presented with bilateral foot drop due to alcohol‐related peripheral neuropathy. There was no history of electrolyte disturbance or altered consciousness. Cranial nerve, bulbar and pyramidal symptoms signs were absent. Nerve conduction studies confirmed the Inadvertently requested neuroimaging brain demonstrated signal change typical central pontine myelinolysis. Asymptomatic myelinolysis occurs rarely in alcoholics absence dysfunction. It is important for physicians be...
Diabet. Med. 27, 696–700 (2010) Abstract Background An interaction between fusidic acid and HMG coenzyme A reductase inhibitors (statins), resulting in rhabdomyolysis, has been described. Pain mild weakness are common presenting symptoms. Case report We four patients with Type 2 diabetes prescribed long‐term statin treatment who, following acid, presented atypically painless, severe flaccid paralysis suggestive of Guillain–Barré syndrome. This, together nerve conduction studies consistent...
A 41-year-old homosexual man presented with a 10-week history of headache without pressure features commencing 10 weeks after new sexual contact. Three days the onset he noticed intermittent, bilateral visual blurring, worse in right eye. The disturbance persisted intermittently and led to his referral local ophthalmology department where was found have papilloedema. There were no other abnormal signs on full examination systems ocular findings. Cerebral imaging studies normal. lumbar...