A5103047147- Cervical Cancer and HPV Research
- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Uterine Myomas and Treatments
- Endometriosis Research and Treatment
- Genital Health and Disease
- Gestational Trophoblastic Disease Studies
- Pregnancy and preeclampsia studies
- Hepatitis B Virus Studies
- Prenatal Screening and Diagnostics
- Gynecological conditions and treatments
- Ectopic Pregnancy Diagnosis and Management
- Sarcoma Diagnosis and Treatment
- Intraperitoneal and Appendiceal Malignancies
- Preterm Birth and Chorioamnionitis
- Pregnancy-related medical research
- Pelvic floor disorders treatments
- Colorectal and Anal Carcinomas
- Molecular Biology Techniques and Applications
- Reproductive System and Pregnancy
- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
- Anorectal Disease Treatments and Outcomes
- Pelvic and Acetabular Injuries
- Renal and related cancers
Chonnam National University Hospital
2012-2024
Chonnam National University Hwasun Hospital
2006-2024
Chonnam National University
2006-2023
Samsung Medical Center
2010-2013
Cheil General Hospital and Women's Healthcare Center
2013
Asan Medical Center
2013
Catholic Kwandong University
2013
University of Ulsan
2013
CHA University
2013
Centre International de Recherche sur le Cancer
2010
This study was conducted to determine whether vaccination with the quadrivalent human papillomavirus (HPV) vaccine after loop electrosurgical excision procedure (LEEP) for high-grade cervical intraepithelial neoplasia (CIN2-3) is effective in preventing recurrence of CIN2-3.Between August 2007 and July 2010, 737 patients aged 20-45 years who were diagnosed CIN2-3 treated by LEEP followed. Three hundred sixty vaccinated HPV (vaccination group), 377 followed without (non-vaccination group)....
In Brief OBJECTIVE: To analyze pregnancy outcomes in young women with stage IA, grade 1 endometrioid adenocarcinoma of the uterus after successful fertility-sparing management using progestin. METHODS: We reviewed medical records 141 who had complete remission progestin treatment. Statistical analysis was performed Student's t test or Mann-Whitney U for continuous variables, χ2 Fisher's exact categorical and log-rank survival comparison. RESULTS: Fifty-four (38.3%) study cohort a history...
To evaluate the value of apparent diffusion coefficient (ADC) histogram analysis for predicting tumor recurrence in patients with uterine cervical cancer treated chemoradiation therapy (CRT).Our institutional review board approved this retrospective study and waived informed consent from each patient. Forty-two (mean age, 56 ± 14 years) biopsy-proven squamous cell carcinoma who underwent both pre-treatment pelvic magnetic resonance imaging a 3.0 T scanner concurrent CRT were included. All...
Genexol-PM is a biodegradable cremophor EL-free polymeric micelle formulation of paclitaxel. Here,we compared efficacy and safety plus carboplatin versus Genexol for ovarian cancer treatment.In this multicenter, randomized, phase II study, patients with International Federation Gynecology Obstetrics IC-IV epithelial were randomly assigned (1:1) to receive 260 mg/m2 or 175 5 area under the curve every 3weeks (6 cycles). The primary endpointwas carbohydrate antigen 125 Response Evaluation...
BACKGROUND Previously proposed criteria for preoperatively identifying endometrial cancer patients at low risk lymph node metastasis remain to be verified. For this purpose, a prospective, multicenter observational study was performed. METHODS Eligible with histologically confirmed underwent magnetic resonance imaging (MRI) and serum antigen 125 (CA 125) testing before surgery. The following were used identify low‐risk patients: 1) endometrioid‐type cancer, 2) no evidence of deep myometrial...
Objective The aim of this study was to evaluate the prognostic value squamous cell carcinoma antigen (SCC-Ag) and optimal cut-off for predicting recurrence in cervical patients with complete remission after primary treatment. Methods We reviewed records 783 cancer who underwent therapy showed at our institution between January 2000 April 2014. A receiver operating characteristic curve used determine SCC-Ag threshold predict recurrence. Cox regression model disease free survival assess...
Bulky or multiple lymph node (LN) metastases are associated with poor prognosis in cervical cancer, and the size number of LN is not yet reflected staging system therapeutic strategy. Although effects surgical resection bulky LNs before standard treatment have been reported several retrospective studies, well-planned randomized clinical studies lacking. Therefore, aim Korean Gynecologic Oncology Group (KGOG) 1047/DEBULK trial to investigate whether debulking surgery prior concurrent...
This study was conducted to determine, using the HPV DNA Chip (HDC) test, whether human papillomavirus (HPV) genotype is predictive of recurrent high-grade cervical intraepithelial neoplasia (CIN; CIN2-3) after a loop electrosurgical excision procedure (LEEP) in postmenopausal women.Between January 2007 and February 2013, 206 women with CIN2-3 were treated LEEP, followed by cytology, Hybrid Capture II (HC2) assay, HDC test. Post-LEEP follow-up performed at 3, 6, 9, 12, 18, 24 months during...
Abstract Malignant transformation of mature cystic teratoma is an uncommon complication. While any the constituent tissues a has potential to undergo malignant transformation, squamous cell carcinoma most commonly associated cancer. We present unusual case postmenopausal woman with synchronous mucinous adenocarcinoma and strumal carcinoid tumor from one two ovarian teratomas (one in each ovary) cervical suggest that cancer be treated by hysterectomy, chemotherapy, radiotherapy.
Purpose The purpose of this study is to evaluate the impact high-risk human papillomaviruses (HPVs) other than HPV 16/18 on natural course atypical squamous cells undetermined significance (ASC-US) or low-grade intraepithelial lesion (LSIL). Materials and Methods population was derived from Korean cohort (2010-2014). Women aged 20 60 who satisfied criteria having both infection abnormal cervical cytology either ASC-US LSIL were recruited five institutions nationwide. Enrolled patients...
The aim of the study was to determine whether human papillomavirus (HPV) L1 capsid protein and HPV genotype can predict disease course as prognostic markers for cervical intraepithelial neoplasia 1 (CIN1).Immunohistochemical staining performed in 101 women who had been confirmed have CIN1 by histologic examination high-risk infection genotyping. analyzed follow-up according over a minimum 12 months.The regressed spontaneously 60.4% women; most cases regression occurred within year (90.9%...
This study was conducted using the human papillomavirus (HPV) DNA chip test (HDC), in order to determine whether HPV genotype is a predictor of residual disease subsequent hysterectomy following loop electrosurgical excision procedure (LEEP) for cervical intraepithelial neoplasia (CIN) 3. Between January 2002 and February 2015, total 189 patients who underwent within 6 months LEEP caused by CIN 3 were included this study. We analyzed their epidemiological data, pathological parameters,...
Objective The aim of this study is to assess the effectiveness oral progestin treatment in women diagnosed with complex atypical hyperplasia (CAH) or grade 1 endometrial cancer (G1EC), who desire preserve their fertility, as alternative a hysterectomy. Methods We reviewed medical records younger than 45 years old that had been CAH G1EC, expressed fertility using at our institution. Women without evidence myometrial invasion on pelvic magnetic resonance imaging scans were included. period was...
Endometrial stromal sarcoma (ESS) is a rare malignancy. Development of extrauterine ESS form endometriosis particularly rare. The majority occurs in areas with preexisting endometriosis. most common site the ovary. We experienced case ovary that arose from multiple disseminated lesions. This disease was managed by total abdominal hysterectomy, bilateral salpingo-oophorectomy, both pelvic lymph nodes dissection, omentectomy, and appendectomy followed postoperative high-dose progesterone...
Cervical intraepithelial neoplasia (CIN) 2 is used as the threshold for treatment decisions. This study was conducted to evaluate clinical efficacy of Hybrid Capture II assay (HC2) and human papillomavirus (HPV) DNA chip test (HDC) detecting HPV in high-grade cervical lesions CIN2 or greater, including adenocarcinoma (CIN2+). Seven hundred forty-one women with abnormal cytology were evaluated HC2, HDC, histological assessment cervix. The overall agreement tests 88.8% (kappa value, 0.61). Of...
Abstract Aim: Our purpose was to investigate lipid peroxide levels, total peroxyl radical‐trapping anti‐oxidative parameter (TRAP) values, and anti‐oxidant vitamin levels in umbilical venous plasma placental tissues, evaluate their roles the pathophysiology of pre‐eclampsia. Methods: Samples tissue homogenates were obtained from 23 normal 18 pre‐eclamptic women at between 33 40 weeks’ gestation. The enzyme‐linked immunosorbent assay method used α‐tumor necrosis factor (TNF‐α), measured by...