A5065056418- Renal cell carcinoma treatment
- Ferroptosis and cancer prognosis
- Cancer Immunotherapy and Biomarkers
- Mathematical Biology Tumor Growth
Chongqing Medical University
2024
Second Affiliated Hospital of Zhengzhou University
2022
Background. With the highest mortality and metastasis rate, kidney renal clear cell carcinoma (KIRC) is one of most common urological malignant tumors not sensitive to chemotherapy radiotherapy. Immunotherapy, which proves be effective a big progression, such as PD-1/PD-L1 inhibitors, all KIRC patients. To predict prognosis immunotherapy response, novel immune checkpoint gene- (ICG-) related model essential in clinics. Methods. From public database-downloaded dataset, ICG-related for...
Dendritic cells (DCs) serve as key regulators in tumor immunity, with activated DCs potentiating antitumor responses through the secretion of pro-inflammatory cytokines and expression co-stimulatory molecules. Most current studies focus on relationship between DC subgroups clear-cell renal-cell carcinoma (ccRCC), but there is limited research connection ccRCC from perspective immune activation. In this study, genes were identified both bulk single-cell RNA-seq data. A prognostic model...