Hatice Asena Sanli
A5069007382- Cytomegalovirus and herpesvirus research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Viral gastroenteritis research and epidemiology
- SARS-CoV-2 and COVID-19 Research
- Legionella and Acanthamoeba research
- COVID-19 Clinical Research Studies
- Influenza Virus Research Studies
- interferon and immune responses
Middle East Technical University
2017-2021
Hacettepe University
2021
Vaccines that incorporate multiple SARS-CoV-2 antigens can further broaden the breadth of virus-specific cellular and humoral immunity. This study describes development immunogenicity VLP vaccine incorporates four structural proteins SARS-CoV-2.VLPs were generated in transiently transfected HEK293 cells, purified by multimodal chromatography, characterized tunable-resistive pulse sensing, AFM, SEM, TEM. Immunoblotting studies verified protein identities VLPs. Cellular immune responses...
Background Vaccines that incorporate multiple SARS-CoV-2 antigens can further broaden the breadth of virus-specific cellular and humoral immunity. This study describes development immunogenicity VLP vaccine incorporates 4 structural proteins SARS-CoV-2. Methods VLPs were generated in transiently transfected HEK293 cells, purified by multimodal chromatography characterized tunable resistive pulse sensing, AFM, SEM, TEM. Immunoblotting studies verified protein identities VLPs. Cellular immune...