Bünyamin Göktaş

ORCID: 0000-0003-2345-7313
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About
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Research Areas
  • Synthesis and Biological Evaluation
  • Computational Drug Discovery Methods
  • Synthesis and biological activity
  • Natural product bioactivities and synthesis
  • Antifungal resistance and susceptibility
  • Cancer therapeutics and mechanisms
  • Synthesis and Characterization of Heterocyclic Compounds
  • Sesquiterpenes and Asteraceae Studies
  • Essential Oils and Antimicrobial Activity
  • Cholinesterase and Neurodegenerative Diseases
  • Phytochemicals and Antioxidant Activities
  • Phytochemistry and Biological Activities
  • Chemical synthesis and alkaloids
  • Peptidase Inhibition and Analysis
  • Plant Toxicity and Pharmacological Properties

Anadolu University
2024

Eskişehir City Hospital
2024

Fırat University
2024

Abstract The tendency toward natural herbal products has increased due to the antibiotic resistance developed by microorganisms and severe side effects of antibiotics commonly used in infectious diseases worldwide. Although antimicrobial studies have been conducted with several species Iris genus, this study is first literature be performed persica L. subsp. aqueous methanol extracts. In study, phenolic content I. was determined LC–MS/MS analysis, vitro activity extracts examined, supported...

10.1002/fsn3.4251 article EN cc-by Food Science & Nutrition 2024-06-24

Monoamine oxidase (MAO) is an enzyme that helps regulate the functions of intracellular amines, as well chemicals such dopamine, serotonin and norepinephrine, in brain its tissues. Active substances are inhibitors monoamine oxidases (MAOs) used treatment anxiety, depression Alzheimer’s disease. Previous studies have shown compounds containing piperazine rings show MAO-A inhibitory activity. Based on these studies, 4 benzothiazole were designed, structures elucidated using spectroscopic...

10.55971/ejls.1497558 article EN European Journal of Life Sciences 2024-08-30

Alzheimer’s disease is a progressive and degenerative brain that negatively affects people’s lives reduces cognitive sensory human functions. Today, there are active ingredients work on disease, containing benzodioxole thiadiazole rings. Acetylcholinesterase terminates neurotransmission in the nervous system leads to accumulation of acetylcholine, overstimulation various receptors consequent impairment neurotransmission. Thiadiazole rings compounds exhibit wide range biological activities,...

10.55971/ejls.1497561 article EN European Journal of Life Sciences 2024-08-30
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