A5005510452- Bariatric Surgery and Outcomes
- Cell Adhesion Molecules Research
- Diet and metabolism studies
- Thyroid Cancer Diagnosis and Treatment
- Nutrition and Health in Aging
- Proteoglycans and glycosaminoglycans research
- Tissue Engineering and Regenerative Medicine
- Mesenchymal stem cell research
- Gastric Cancer Management and Outcomes
- Cellular Mechanics and Interactions
- Galectins and Cancer Biology
- Cancer, Hypoxia, and Metabolism
- Polymer Surface Interaction Studies
- Metabolism and Genetic Disorders
- Liver Disease Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Antibiotics Pharmacokinetics and Efficacy
- Chemokine receptors and signaling
- Biomedical Ethics and Regulation
- Nutritional Studies and Diet
- Body Contouring and Surgery
- Anodic Oxide Films and Nanostructures
- Cancer-related Molecular Pathways
- Cancer therapeutics and mechanisms
- Nanoparticle-Based Drug Delivery
Pegaso University
2021-2023
University of Campania "Luigi Vanvitelli"
2010-2019
Società Italiana di Cardiologia
2017
University of Naples Federico II
2006-2016
European Society of Anaesthesiology
2015
Applied Biotechnology Institute
2006
Institute of Protein Biochemistry
1999-2002
University of Siena
1997-2001
University of Chieti-Pescara
2001
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"
2001
Glioblastoma multiforme is the most common and aggressive primary brain cancer with only ∼3% of patients surviving more than 3 years from diagnosis. Several mechanisms are involved in drug radiation resistance to anticancer treatments among them one important factors tumor microenvironment status, characterized by cell hypersecretion interleukins cytokines. The aim our research was synthesis a nanocarrier quercetin combined temozolomide, enhance specificity efficacy this commonly used...
Butyric acid (BA) has been reported to induce anticancer effects on hepatocellular carcinoma (HCC) cells both in vitro and vivo. However, its delivery release cancer tissues must be optimized. On the basis of these requirements, we prepared liposomes coated with chitosan uncoated types were loaded BA through a thin-film hydration method. The or had mean hydrodynamic size 83.5 110.3 nm, respectively, homogeneous distribution particles. For evaluation biological nanoformulations,...
The aim of this study is based on the evaluation anticancer, anti‐inflammatory activities, and cellular uptake hyaluronic acid nanohydrogel quercetin tested alone in combination to a macrolide derivative rapamycin RAD001 (everolimus) hormone‐responsive breast cancer cell line MCF‐7. Biological investigations were focused receptor mediated internalization its abilities reduce secretion several cytokines (IL‐8, IL‐6, IL‐19), VEGF, metalloproteases (MMP‐2, MMP‐9) under pro‐inflammatory...
Adipose tissue is an easily accessible source of stem cells for use in regenerative medicine. In the literature, different methods have been used to stimulate acquisition neuronal characteristics by adipose-derived (ADSC). Herein we study growth and differentiation potential ADSC seeded onto a porous polycaprolactone (PCL) scaffold. The objective this demonstrate that PCL can be as scaffold support reconstruction new nervous using adipose cells. We previously shown undifferentiated adhere...
The mechanism by which estradiol (E2) acts on cell proliferation is still unclear. In this paper, we report the results of a series experiments in an attempt to elucidate effector pathway(s) involved coupling E2 receptors binding cellular growth response leiomyoma cells (LSMC). Under conditions E2-dependent growth, treatment LSMC triggers rapid and transient activation MAP-kinase pathway. Interestingly, demonstrate that early downstream signal transduction events determined E2-stimulation...
The aim of this paper is based on the use a hyaluronic acid hydrogel Quercetin tested alone and in combination to an inhibitor Aurora Kinase type A B (SNS-314) human medullary papillary thyroid cancer cells. Biological investigations were focused cellular uptake hydrogel, cell viability, antioxidant, cytokines secretion studies. delivered from show time CD44 dependent interaction with both lines significant anti-inflammatory effects. Combination SNS-314 leads synergistic cytotoxic effect TT...
Bariatric surgery candidates often show preoperative micronutrient deficiency. Although it is documented that a comprehensive assessment should be conducted preoperatively to correct the deficiencies before surgery, no previous studies have been effective in correcting sufficient time prior surgery. Our aim was identify and them
Abstract Background One of the most effective surgeries for sustainable weight loss in morbidly obese patients is laparoscopic sleeve gastrectomy ( LSG ). The present study aimed to assess adherence with respect following post‐operative dietary requirements and micronutrient supplementation, as well investigate their perceived barriers achieving optimal adherence. Methods Retrospective data analysis was performed (3, 6, 9 12 months after LSG) using medical records 96 who had undergone at our...