A5033725785- Phytochemistry Medicinal Plant Applications
- Essential Oils and Antimicrobial Activity
- Insect Pest Control Strategies
- Heavy Metals in Plants
- Psidium guajava Extracts and Applications
- Ethnobotanical and Medicinal Plants Studies
- Public Health in Brazil
- Nanoparticles: synthesis and applications
- Medicinal Plant Extracts Effects
- Traditional and Medicinal Uses of Annonaceae
- Agricultural and Food Sciences
- Research on Leishmaniasis Studies
- Plant Pathogens and Fungal Diseases
- Piperaceae Chemical and Biological Studies
- Trypanosoma species research and implications
- Botanical Research and Applications
- Antimicrobial Resistance in Staphylococcus
- Aluminum toxicity and tolerance in plants and animals
- Sesquiterpenes and Asteraceae Studies
- Bioactive Natural Diterpenoids Research
- Bee Products Chemical Analysis
- Antibiotic Resistance in Bacteria
- Phytochemistry and Biological Activities
- Seed Germination and Physiology
- Phytochemistry and biological activities of Ficus species
Universidade Regional do Cariri
2013-2024
Centro Universitário do Norte
2021-2023
Faculdade de Medicina do ABC
2020-2023
Rede de Química e Tecnologia
2014
<italic>Eugenia uniflora</italic>L. (Myrtaceae family), also known as “pitanga”, is a tree species widely used in popular medicine.
Drug resistance in the treatment of neglected parasitic diseases, such as leishmaniasis and trypanosomiasis, has led to search development alternative drugs from plant origins. In this context, essential oil extracted by hydro-distillation Lantana camara leaves was tested against Leishmania braziliensis Trypanosoma cruzi. The results demonstrated that L. inhibited T. cruzi with IC50 201.94 μg/mL 72.31 μg/mL, respectively. found be toxic NCTC929 fibroblasts at 500 (IC50 = 301.42 μg/mL)....
The fruit fly Drosophila melanogaster is often utilized in genetic research, and the last decades, it has become one of best organisms for studies human diseases toxicological research. Mercury chloride (HgCl2), main representative mercury compounds, target numerous investigations, not only because its intrinsic toxicity but also accounts elemental since latter converted to Hg+2 by oxidation. Eugenia jambolana Lam. Myrtaceae, known Brazil as "jambolão", great interest medicinal applications,...
Rhaphiodon echinus is a weed plant used in the Brazilian folk medicinal for treatment of infectious diseases. In this study, essential oil R. leaf was investigated its antimicrobial properties.The chemical constituents were characterized by GC-MS. The properties determined studying microdilution method effect alone, and combination with antifungal or antibiotic drugs against fungi Candida albicans, krusei tropicalis microbes Escherichia coli, Staphylococcus aureus Pseudomonas. addition, iron...
The guava fruit, Psidium guajava var. pomifera (Myrtaceae family), is a native plant from South America. Its leaves and fruits are widely used in popular medicine tropical subtropical countries. Drosophila melanogaster has been as one of the main model organisms genetic studies since 1900s. extensive knowledge about this species makes it most suitable to study many aspects toxic compound effects. Due lack on effects bioactive compounds present P. essential oil, we performed phytochemical...
Background: The challenge of antibiotic resistance and the emergence new infections have generated considerable interest in exploration natural products from plant origins as combination therapy. In this context, crude ethanolic extract (CEE), ethyl acetate fraction (EAF), methanolic (MF) Anacardium microcarpum were tested alone or with antibiotics (amikacin, gentamicin, ciprofloxacin, imipenem) against Escherichia coli , Pseudomonas aeruginosa Staphylococcus aureus . Methods: Antibiotic...
The combination of antibiotics with natural products has demonstrated promising synergistic effects in several therapeutic studies.The aim this study was to determine the effect a an ethanol extract Myracrodruon urundeuva Fr. All. (Anacardiaceae) (aroeira plant) and its essential oil six antimicrobial drugs against multiresistant strains Staphylococcus aureus Escherichia coli from clinical isolates.After identification chemical components by GC-MS, antibacterial activity assessed determining...
Environmental stressors such as mercury are important for the search of substances to lower induced oxidative damage. Accordingly, secondary metabolites from plants with antioxidant activity represent an interesting alternative. The aim this work was evaluate cytoprotective effect ethanol extract Eugenia uniflora against chloride. main phytochemicals were quantified by HPLC. chelating evaluated using O-phenanthroline method. assayed bacterial and plant models. cytotoxic negative geotaxis...
The present study was aimed to synthesize silver nanoparticles (AgNPs) from the aqueous extracts of Odontosoria chinensis (L.) J. Sm. and synthesized AgNPs were examined for their biopotentials. added 1 mM AgNO3 solution with different ratios viz., 0.5: 9.5, 1:9, 1.5: 8.5 2: 8 reduction Ag ions. After reduction, analyzed spectroscopically further confirmation. characterized by pH, ultra violet-visible spectroscopy (UV-Vis), Fourier transform-infra red (FT-IR), scanning electron...
Context Melissa officinalis subsp. inodora Bornm. (Lamiaceae) has been used since ancient times in folk medicine against various diseases, but it not investigated protozoa.Objective To evaluate the activities of M. Leishmania braziliensis, infantum and Trypanosoma cruzi as well its cytotoxicity fibroblast cell line.Materials methods The fresh leaves were chopped into 1 cm2 pieces, washed macerated with 99.9% ethanol for 72 h at room temperature. Antiparasitic activity was accessed by direct...
RESUMO A resistência de fungos do gênero Candida aos fármacos químicos tem lançado o desafio se identificar novas substâncias que possuam atividade antibiótica ou venham a modular efeito produtos atualmente usados contra candidíase. O presente estudo avaliou antifúngica óleo essencial Lippia sidoides Cham. e timol, sobre cepas Candida. Inicialmente os foram testados frente 16 fúngicas pela técnica difusão em meio sólido, permitiu selecionar linhagens para continuidade da pesquisa. Com as...
This study aims to verify the chelating, antioxidant and cytoprotective activities of Eugenia uniflora in a eukaryotic prokaryotic model. Ethanolic extract, as well tannic flavonoid fractions, were prepared from samples obtained species which analyzed by LC-MS. The activity through FRAP method showed that fraction had lowest EC50. suggested compounds identified extract fractions quercetin derivatives, myricetin, gallic acid, vanillic quinic acid catechin. Regarding fraction, reduction...
Leishmanioses e tripanossomíases são doenças parasitárias globalmente difundidas com elevado índice de mortalidade morbidade. O arsenal terapêutico é restrito efeitos colaterais indesejáveis. No entanto, a biodiversidade plantas brasileiras representa rica fonte novos compostos potencial antiparasitário. geraniol um monoterpeno encontrado em como Cymbopogon winteranus martinii . Ocitronelal fitoconstituínte monoterpenóide Eucalyptus citriodora citratus. objetivo deste estudo foi avaliar...