A5027615571- GaN-based semiconductor devices and materials
- Antimicrobial agents and applications
- Advanced Control Systems Optimization
- Traditional Chinese Medicine Analysis
- ZnO doping and properties
- Phytochemistry and Biological Activities
- Antimicrobial Peptides and Activities
- Ga2O3 and related materials
- Fault Detection and Control Systems
- Crystallography and molecular interactions
- Essential Oils and Antimicrobial Activity
- Natural product bioactivities and synthesis
- Semiconductor Quantum Structures and Devices
- Plant-based Medicinal Research
- Crystallization and Solubility Studies
- Antibiotic Resistance in Bacteria
- Chromatography in Natural Products
- Metabolomics and Mass Spectrometry Studies
- Microbial Metabolites in Food Biotechnology
- Polysaccharides and Plant Cell Walls
- Synthesis and Properties of Aromatic Compounds
- Click Chemistry and Applications
- X-ray Diffraction in Crystallography
- Advanced Chemical Physics Studies
- Chemical Reaction Mechanisms
Hunan University
2011-2024
Huaihua University
2021
Hua Medicine (China)
2018
Hunan University of Traditional Chinese Medicine
2012
Kyma Technologies (United States)
2003-2009
Rensselaer Polytechnic Institute
2008
Virginia Commonwealth University
2003-2005
East China University of Science and Technology
1996-1999
Kadsua coccinea (K. coccinea) has long been used as a fruit and folk medicine; however, the composition of its leaves activities constituents have seldom studied. A total 98 chemical constituents, including 53 phenolic acids, 41 flavonoids, 4 lignans, were identified from plant kadsua by UHPLC-Q-Exactive Orbitrap Mass spectrometry. All these chemicals reported for first time in leaves, 95 them coccinea. The biological potential extracts K. (EKL) was evaluated vitro antioxidant assay...
polysaccharides have a variety of pharmacological effects. The commonly used extraction methods include traditional hot water extraction, alkaline enzymatic hydrolysis method, ultrasonic-assisted etc., but there are problems such as low yield, high temperature, cost, strict conditions, and insufficient environmental protection. In this study, crude polysaccharide from the
We report the development of 520–540nm green light emitting diodes (LEDs) grown along nonpolar a axis GaN. GaInN∕GaN-based quantum well structures were in homoepitaxy on both, a-plane bulk GaN and r-plane sapphire. LEDs show higher, virtually dislocation-free crystalline quality three times higher output power when compared to those Both much smaller wavelength blue shift for increasing current density (<10nm 0.1to12.7A∕cm2) than conventional polar c axis.
The steric effect is one of the most widely used chemical concepts in chemistry, yet a generally accepted implementation its formulation and quantification from theoretical viewpoint, if even possible, still an unaccomplished task. Based on energetics viewpoint our earlier proposal using Weizsäcker kinetic energy as contribution well recent work force reliable local descriptor to account for origin stereoselective propensity reactions, this work, we systematically examine behavior general...
The wide spread of drug-resistant bacteria, especially methicillin-resistant Staphylococcus aureus (MRSA), poses a tremendous threat to global health. Of particular concern, resistance vancomycin, linezolid, and daptomycin has already been reported in clinical MRSA strains. New antibacterial agents are urgently needed overcome this crisis. Here, we designed synthesized series ruthenium-based via targeting bacterial membrane integrity. Structure-activity relationship studies demonstrated that...
Molecular acidity is an important physiochemical property essential in many fields of molecular studies, but efficient and reliable computational approach to make accurate predictions still missing. In this work, based on our previous studies use gas phase electronic properties such as electrostatic potential valence natural atomic orbitals the acidic atom leaving proton, we demonstrate here that different approaches can be employed tackle problem. To end, employ 196 singly, doubly, triply...
Duhaldea nervosa (Wallich ex Candolle) A. Anderberg has been traditionally used as a food spice and also in folk medicine for treating traumatic injury relieving rheumatism, especially accelerating the healing of fracture. However, so far we are aware, chemical constituents have not fully investigated. In this study, practical method mass spectral trees similarity filter, data-mining technique, was developed evaluated rapid detection identification complicated based on ultra-high-performance...
Ruthenium complex <bold>Ru(II)-3</bold> functionalized with benzothiophene showed good antimicrobial activity against <italic>Staphylococcus aureu</italic>s <italic>in vivo</italic>.
Corannulene is an interesting yet special molecule, which has witnessed widespread applications. It aromatic, but not planar and the total number of 20 π electrons in conflict with Hückel's 4n + 2 rule. In this work, we design a series analogous model systems based on molecule central ring size extended from five members to three eight members. A theoretical analytical tools available literature are employed systematically examine their structure, aromaticity reactivity properties. We found...
In the present study, a novel water-soluble polysaccharide (DNP−1) was isolated and purified from root of Duhaldea nervosa via column chromatography. Structural analyses indicated that DNP−1 had linear backbone consisting (2→1)-linked β-D- fructofuranosyl residues, ending with (2→1) bonded α-D-glucopyranose. homogeneous an average molecular weight 3.7 kDa. Furthermore, anti-inflammatory activity investigated in vitro. The concentration pro-inflammatory cytokines, including NO, TNF-α, MCP-1,...
A novel approach for the acylation of azauracil derivatives with aldehydes has been developed utilizing sodium decatungstate (NaDT) as a photocatalyst. This method demonstrates broad substrate tolerance and yields moderate to excellent outcomes. Notably, it aligns green chemistry principles by eliminating oxidants, eco-friendly energy sources, offering high scalability operational simplicity.
A Ru-based antimicrobial agent (RuBZ) containing benzonitrile was prepared that exhibits robust potency against S. aureus in vitro , as well low toxicity and high efficacy vivo .
Duhaldea nervosa (D. nervosa) has been used for treatment of bone fracture by external use. Thus, the percutaneous absorption was crucial to effect D. nervosa, especially constituents absorption. However, in vivo were never investigated date. In this study, an efficient method developed identification using UHPLC-Q-Exactive Orbitrap MS and microdialysis technique. A total 20 including 15 chlorogenic acid analogues, 3 amino acids, 2 organic acids unambiguously or tentatively identified based...