A5088373725- Bacterial Genetics and Biotechnology
- Bacterial biofilms and quorum sensing
- Antimicrobial Resistance in Staphylococcus
- Antimicrobial Peptides and Activities
- Genomics and Phylogenetic Studies
- Probiotics and Fermented Foods
- Fungal Infections and Studies
- Bacteriophages and microbial interactions
- Microbial Community Ecology and Physiology
- Methane Hydrates and Related Phenomena
- Plant Pathogens and Fungal Diseases
Rutgers, The State University of New Jersey
2021-2025
Microbial symbionts of vertebrate skin have an important function in defense the host against pathogens. In particular, emerging chytrid fungus Batrachochytrium dendrobatidis , causes widespread disease amphibians but can be inhibited via secondary metabolites produced by many different skin‐associated bacteria. Similarly, fungal pathogens terrestrial salamander eggs Mariannaea elegans and Rhizomucor variabilis are also a variety Indeed, probiotic therapy diseases is recent approach...
Pseudomonas aeruginosa and Staphylococcus aureus are primary bacterial pathogens isolated from the airways of cystic fibrosis patients. P. produces secondary metabolites that negatively impact fitness S. aureus, allowing to become most prominent bacterium when species co-cultured. Some these inhibit respiration. SrrAB is a staphylococcal two-component regulatory system (TCRS) responds alterations in respiratory status helps transition between fermentative metabolisms. We used mutant strains...
Transcriptional reporters are reliable and time-tested tools to study gene regulation. In Staphylococcus aureus, β-galactosidase (lacZ)-based genetic screens not widely used because of the necessity selectable markers for strain construction production staphyloxanthin pigment, which obfuscates results. We describe a series vectors that allow markerless insertion codon-optimized lacZ-based transcriptional reporters. The code different ribosomal binding sites, allowing tailored lacZ...
Abstract Transcriptional reporters are reliable and time-tested tools to study gene regulation. In Staphylococcus aureus , β-galactosidase ( lacZ )-based genetic screens not widely used because of the necessity selectable markers for strain construction production staphyloxanthin pigment which obfuscates results. We describe a series vectors that allow markerless insertion codon-optimized -based transcriptional reporters. The encode different ribosomal binding sites allowing tailored...