In this review study, efficacy and side effects of interferon alfa-2b (IFN-α2b) in treating the common ocular surface disorders is described. It was found that 1 million IU/mL topical alpha-2b administered four times daily effective various disorders, including vernal keratoconjunctivitis, Ocular squamous neoplasia, conjunctival papilloma, melanoma. The treatment showed a significant decrease symptoms signs diseases and, some cases, resulted tumor regression with high tolerance safety....

To compare the recurrence rate and surgical outcomes of amniotic membrane transplantation (AMT) free conjunctival autograft (CAT) for pterygium surgery.In this prospective study, 60 patients with primary were randomly assigned to two groups CAT or AMT compared in terms rate, mean healing time corneal epithelial defects, level inflammation, complications.The ± SD age was 48.98 9.8 years (range, 27-71 years). 73.3% men, 26.7% women. The did not differ respect demographic characteristics (P >...

Hyperimmunoglobulin E syndrome (HIES) or Job’s is a rare immunodeficiency disease with less than 200 cases reported worldwide, among which few are lesions due to herpes simplex virus (HSV) human papillomavirus (HPV). This case study presents of HIES coinfection HSV and HPV. A 12-year-old boy, previously diagnosed HIES, presented large conjunctival mass lesion. The presence HPV in the lesion was confirmed by biopsy using line-probe assay method detect genome. However, did not respond anti-HPV...

Journal of ophthalmic and Vision research 2015; Vol. 10, No. 1 Dear Editor, In the treatment unilateral total limbal stem cell deficiency (LSCD), conjunctival autograft (CLAU) surgery taken from healthy fellow eye with or without amniotic membrane transplantation (AMT) is one main therapeutic alternatives.[1] There are some controversies regarding optimal size graft necessary for complete stable epithelialization cornea.[2,3] Traditionally, two 60° grafts have been used.[4] Few attempts made...

The aim of this study was to evaluate the safety and efficacy collagen cross-linking (CXL) in advanced progressive keratoconus with a maximum keratometry (Kmax) value more than 58 diopters (D).This prospective interventional case series involved patients Kmax D. best-corrected visual acuity (BCVA), uncorrected (UCVA), Kmax, mean (Kmean) value, corneal astigmatism, thinnest thickness before surgery 24 months after CXL were determined for 30 eyes 27 patients. A Pentacam used measure...

This study was conducted to determine the demographics, clinical features, severity, and activity of thyroid eye disease (TED) in patients a referral center north Iran.Patients with TED who were referred Amir-Almomenin Hospital, Rasht, Iran from March 2012 2014 enrolled this cross-sectional study. The measurements proptosis, lid width, lagophthalmos, extraocular muscle function, visual acuity recorded. ophthalmopathy scored according score (CAS).TED diagnosed 103 mean age 42.1 ± 13.91 years....

Purpose: To describe the technique and outcomes of limbal stem cell–sparing lamellar keratoplasty (LSCS-LKP) for management advanced keratoglobus (KGB). Methods: In a sequential interventional case series from March 2010 to December 2012, 8 eyes 6 patients with KGB underwent an LSCS-LKP. Three had isolated KGB, 2 were affected Ehlers–Danlos syndrome, other subject osteogenesis imperfecta. Epithelial healing, anatomical results (corneal thickness keratometry), visual evaluated after this...

In the present study, we investigated effect of two doses atropine eye drops versus placebo on myopia progression in children and adolescents.In this double-blind, randomized clinical trial, 67 patients aged 6 to 18 years with -2 -6 D were enrolled receive a drop, 0.1%, or 0.01% ophthalmic solution (one drop per night for months). All participants followed-up one year after beginning study (at zero, one, three, six, 12 months) their spherical equivalent (SE), axial length (AL), anterior...

Retrobulbar block is one of the chosen methods for local anesthesia in cataract surgery. Since it a painful procedure, using analgesic and sedative drugs recommended. Current medications have side effects evaluating new or uses existing safer necessary.The aim this study was to compare administration melatonin acetaminophen on pain hemodynamic changes during retrobulbar block.In double-blinded randomized trial, 180 patients undergoing surgery were randomly divided into three groups:...

The current randomized clinical trial was conducted to determine the influence of topical ketorolac combination with steroids on anterior segment inflammation and other adverse effects following phaco-surgery for pseudoexfoliation (PEX) syndrome.A total eighty-eight patients PEX cataracts who had undergone phacoemulsification participated in trial.They were randomly placed into one two groups, which received betamethasone (0.1%) chloramphenicol (5%) weeks, either or without eye drops...

Objective To evaluate and compare choroidal thickness (CT) between patients with Meniere's disease (MD) a control group. Methods This case–control analytical study was conducted on 37 subjects MD healthy subjects. Subfoveal CT (SCT), large vessel (LCV) layer thickness, mean subfoveal LCV thickness/mean SCT ratio were measured using enhanced‐depth imaging optical coherence tomography (EDI‐OCT) in the eyes side (ipsilateral), contralateral eyes, Results A statistically significant difference...

To assess the longitudinal changes of choroidal thickness using enhanced depth imaging optical coherence tomography (EDI-OCT) during pregnancy and postpartum.The study included 23 eyes healthy pregnant women nonpregnant women. Choroidal was measured manually with EDI-OCT at seven locations: The fovea, 500, 1000, 1500 μm temporal (T) from fovea nasal (N) fovea. Measurements were obtained each trimester 6 weeks postpartum in follicular phase menstrual cycle for control group.The mean subfoveal...

To evaluate the correlation of corneal elevation and difference with severity keratoconus.Anterior posterior elevations both conventional enhanced best-fit spheres (using rotating Scheimpflug camera) were measured. Front back extrapolated from map Belin/Ambrỏsio Enhanced Ectasia Display system. Data correlated maximum keratometry, minimal thickness, keratoconus as assessed by Amsler-Krumiech classification keratoconus.Ninety eyes 55 patients different clinical stages evaluated. There was a...

To determine the benefits of performing preoperative spectral domain optical coherence tomography (SD-OCT) and to identify occult macular pathologies in patients scheduled for routine cataract surgery.In this cross-sectional study, SD-OCT scans were performed on all with clinically undetected abnormalities who surgery. Patients evident excluded from study. A retinal specialist reviewed scans. The severity was determined using Oxford Clinical Cataract Classification Grading System.Of 598...