- Advanced Sensor and Energy Harvesting Materials
- Tactile and Sensory Interactions
- Dielectric materials and actuators
- Conducting polymers and applications
- Plant tissue culture and regeneration
- Glass properties and applications
- Seismic Imaging and Inversion Techniques
- Sirtuins and Resveratrol in Medicine
- Spacecraft Design and Technology
- Membrane Separation and Gas Transport
- Laser Material Processing Techniques
- Analytical Chemistry and Chromatography
- Hydraulic Fracturing and Reservoir Analysis
- Pharmacogenetics and Drug Metabolism
- Plant Reproductive Biology
- Toxin Mechanisms and Immunotoxins
- Plant Stress Responses and Tolerance
- Plant Gene Expression Analysis
- Extraction and Separation Processes
- Advanced Battery Materials and Technologies
- Graphite, nuclear technology, radiation studies
- Polymer composites and self-healing
- Cold Atom Physics and Bose-Einstein Condensates
- Vibration Control and Rheological Fluids
- Advanced Battery Technologies Research
Korea Research Institute of Bioscience and Biotechnology
2020-2025
Chonnam National University
2011-2024
Hanyang University
2016-2024
Jet Propulsion Laboratory
2021-2023
Korea Photonics Technology Institute
2020-2023
Korea Research Institute of Chemical Technology
2022
Soon Chun Hyang University Cheonan Hospital
2022
Bio-Medical Science (South Korea)
2022
University of Illinois Urbana-Champaign
2021
Sangmyung University
2020
A highly sensitive, wearable, and multimodal skin sensor that uses hierarchically engineered elastic carbon nanotube microyarns is described. Piezocapacitive all-carbon sensors simultaneously detect heterogeneous external subtle stimuli, including mechanical deformation, touch, temperature or humidity gradients, even biological variables with different dipole moments, which enables in situ human monitoring as well recognition of robot-human-environmental interface. As a service to our...
Abstract An extreme diversity of substrates and catalytic reactions cytochrome P450 (P450) enzymes is considered to be the consequence evolutionary adaptation driven by different metabolic or environmental demands. Here we report presence numerous natural variants BM3 (CYP102A1) within a species Bacillus megaterium . Extensive amino acid substitutions (up 5% total 1049 residues) were identified from variants. Phylogenetic analyses suggest that this gene evolve more rapidly than rRNA locus....
Biological cellular structures have inspired many scientific disciplines to design synthetic that can mimic their functions. Here, we closely emulate biological in a rationally designed multicellular hybrid ion pump, composed of hydrogen-bonded [EMIM+][TFSI-] pairs on the surface silica microstructures (artificial mechanoreceptor cells) embedded into thermoplastic polyurethane elastomeric matrix extracellular matrix), fabricate ionic skins. Ionic mechanoreceptors engage hydrogen...
Capabilities for continuous monitoring of pressures and temperatures at critical skin interfaces can help to guide care strategies that minimize the potential pressure injuries in hospitalized patients or individuals confined bed. This paper introduces a soft, skin-mountable class sensor system this purpose. The design includes pressure-responsive element based on membrane deflection battery-free, wireless mode operation capable multi-site measurements strategic locations across body. Such...
The development of advanced materials capable autonomous self-healing and mechanical stimulus sensing in aquatic environments holds great promise for applications underwater soft electronics, robotics, water-resistant human-machine interfaces. However, achieving superior properties effective simultaneously an environment is rarely feasible. Here, we present ultrafast molecularly engineered piezo-ionic elastomer inspired by the cephalopod's suckers, which possess mechanosensitive ion...
Wrinkled elastomeric templates prepared by stretching and releasing are utilized for demonstrating highly sensitive, simple, low-cost piezocapacitive pressure sensors over large area.
Artificial smart designs inspired by structural and functional features of biological organisms have opened new avenues to develop high-performance flexible tactile sensors advanced artificial sensory systems.
Abstract The effect of nanoscale confinement on the glass transition temperature, T g , freely standing polystyrene (PS) films was determined using temperature dependence a fluorescence intensity ratio associated with pyrene dye labeled to polymer. third peak that first in 1‐pyrenylmethyl methacrylate‐labeled PS (MApyrene‐labeled PS) decreased decreasing and intersection linear dependences rubbery glassy states yielded measurement . sensitivity this method also shown bulk, supported...
We reported the development of a transparent stretchable crack-enhanced microfluidic capacitive sensor array for use in E-skin applications. The was fabricated through simple lamination process involving two silver nanowire (AgNW)-embedded rubbery channels arranged crisscross fashion. sensing performance optimized by testing variety liquids injected into channels. External mechanical stimuli applied to induced liquid penetrate deformed microcracks on rubber channel surface. increased...
Invasive aspergillosis is a critical complication in immunocompromised patients with hematologic malignancies or viral pneumonia caused by influenza virus SARS‑CoV‑2. Although early and accurate diagnosis of invasive can maximize clinical outcomes, current diagnostic methods are time-consuming poorly sensitive. Here, we assess the ability 2-deoxy-2-18F-fluorosorbitol (18F-FDS) positron emission tomography (PET) to specifically noninvasively detect Aspergillus infections. We show that 18F-FDS...
Soft robotics systems are currently under development using ionic electroactive polymers (i-EAP) as soft actuators for the human-machine interface. However, this endeavor has been impeded by dilemma of reconciling competing demands force and strain in i-EAP actuators. Here, authors present a novel design called "ions-silica percolated dielectric elastomer (i-SPIDER)", which exhibits liquid-confined silica microstructures that effectively resolve chronic issue conventional The i-SPIDER...
Conformable and reliable ionic textiles on the basis of sheath-core carbon nanotube microyarns are utilized for implementing highly sensitive piezocapacitive pressure sensors.
High-performance, wearable, and self-powered mechanical sensors for human health monitoring, motion detection systems, human–machine interfaces are attracting attention owing to the increased interest in green energy. Piezoelectric triboelectric effects being exploited develop various types of sensors; however, unresolved issues such as complicated processes limitations material selection practical applications remain. A type effective sensor based on hybrid triboelectric–flexoelectric...
De novo shoot regeneration, characterized by the emergence of adventitious shoots from excised or damaged tissues organs in vitro, is regulated complex interplay between genetic and epigenetic regulatory mechanisms. However, specific effect histone deacetylation on regeneration remains poorly understood. This study investigated effects trichostatin A (TSA), a deacetylase inhibitor, callus derived root explants. TSA-treated explants exhibited pronounced greening substantially increasing...
The oat (Avena sativa L.) is a grain of the Poaceae grass family and contains many powerful anti-oxidants, including avenanthramides as phenolic alkaloids with anti-inflammatory, anti-oxidant, anti-itch, anti-irritant, anti-atherogenic activities. Here, treatment germinating oats methyl jasmonate (MeJA) or abscisic acid (ABA) resulted in 2.5-fold (582.9 mg/kg FW) 2.8-fold (642.9 increase avenanthramide content, respectively, relative to untreated controls (232.6 FW). Moreover, MeJA ABA...
A large set of <i>Bacillus megaterium</i> CYP102A1 mutants are known to metabolize various drugs form human metabolites. Omeprazole (OMP), a proton pump inhibitor, has been widely used as an acid inhibitory agent for the treatment gastric hypersecretion disorders. It is primarily metabolized by CYP2C19 and CYP3A4 5′-OH OMP sulfone product, respectively. was recently reported that several can oxidize racemic <i>S</i>-OMP these further 5′-COOH OMP. Here, we report <i>S</i>-...
We demonstrate an ionic polymer artificial mechanotransducer (i-PAM) capable of simultaneously yielding efficient wide bandwidth and a blocking force to maximize human tactile recognition in soft feedback. The unique methodology the i-PAM relies on interpenetrating nanofibrillar network that is formed at interface (i) thermoplastic polyurethane matrix with liquid 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([EMIM]+[TFSI]−) (ii)...
Abstract We report the high production of stilbenes, including resveratrol and viniferin, in grapevine ( Vitis labruscana L.) cell cultures through elicitation with methyl jasmonate (MeJA) stevioside (STE). Methyl-β-cyclodextrin (MeβCD) is widely used as a solubilizer for production. For first time, we STE stilbene plant cultures. MeJA was most effective elicitor activating VvSTS expression stimulating biosynthesis The maximum concentration δ-viniferin (892.2 mg/L) small amount trans...