A5100380800- Autism Spectrum Disorder Research
- EEG and Brain-Computer Interfaces
- Molecular Sensors and Ion Detection
- Phosphorus compounds and reactions
- Family and Disability Support Research
- Sulfur Compounds in Biology
- Behavioral and Psychological Studies
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Gaze Tracking and Assistive Technology
- Organophosphorus compounds synthesis
- Receptor Mechanisms and Signaling
- Luminescence and Fluorescent Materials
- Speech and Audio Processing
- PI3K/AKT/mTOR signaling in cancer
- Neuroendocrine regulation and behavior
- Sleep and Wakefulness Research
- Quinazolinone synthesis and applications
- Blind Source Separation Techniques
- Disability Education and Employment
- Emotion and Mood Recognition
- Advanced Synthetic Organic Chemistry
- Genetics and Neurodevelopmental Disorders
- Complement system in diseases
- Inorganic and Organometallic Chemistry
- Monoclonal and Polyclonal Antibodies Research
Shanghai Mental Health Center
2024
Shanghai Jiao Tong University
2024
Jining University
2024
Zhejiang University
2005-2022
North China University of Technology
2022
Kunming University of Science and Technology
2022
China Three Gorges Corporation (China)
2021
Wuhan Children's Hospital
2020
Institute of Automation
2020
University of Connecticut
2019
A brain–blood barrier permeable probe was developed for fluorogenically sensing nitrosative stress caused by brain vascular injury.
Summary Background Autism spectrum disorders ( ASD s) are a heterogeneous group of neurodevelopmental that display complicated behavioral symptoms. Methods Using gene expressing profiling and the weighted co‐expression network analysis WGCNA ), we studied genes coregulated by similar factors such as genetic variants or environmental effects in hippocampus an animal model autism. Results From microarray data, identified 21,388 robustly expressed which 721 were found to be differently valproic...
Rash is one of the primary dose-limiting toxicities Akt (protein kinase B) inhibitors in clinical trials. Here, we demonstrate inhibition Akt2 isozyme may be a driver for keratinocyte apoptosis, which promotes us to search new selective with an improved cutaneous safety property. According our previous research, compound 2 selected further optimization overcoming disadvantages 1, including high and toxicity against HaCaT keratinocytes. The dihedral angle-based design molecular dynamics...
Equipping a fluorophore with two ONOO<sup>−</sup>-specific reaction triggers yielded probe able to report various degrees of nitrosative stress in live cells.
Abstract Antibodies raised against defined phosphorylation sites of the microtubule‐associated protein tau are widely used in scientific research and being applied clinical assays. However, recent studies have revealed an alarming degree non‐specific binding found these antibodies. In order to quantify compare specificity phospho‐tau antibodies other post‐translational modification site‐specific general, a measure is urgently needed. Here, we report robust flow cytometry assay using human...
Abstract The Wittig reactions of three semistabilized phosphorus ylides generated in situ from the corresponding phosphonium salts with aldehydes water without any organic cosolvent were investigated. Most olefination completed within between 5 min and 4.5 h refluxing containing 1.5 equiv LiOH 1.4 M LiCl to afford products 65–100% yields. E∶Z selectivity depended not only on substituent attached benzene ring but also bound aromatic aldehydes. promotes aqueous suppresses decomposition ylide or salt.
As an effective method, feature selection can reduce computational complexity and improve classification performance. A number of criteria exist for using labeled data, unlabeled data pairwise constraints, most which are based on the Euclidean distance. In this paper, we propose a filter method with aiming to jointly evaluate subset metric learning. Two designed well-known Kullback-Leibler divergence measuring difference between must-link constraints cannot-link that indicate discrimination...
Rapid Serial Visual Presentation (RSVP)-based Brain-Computer Interface (BCI) is an efficient information detection technology by detecting event-related brain responses evoked target visual stimuli. However, a time-consuming calibration procedure needed before new user can use this system. Thus, it important to reduce efforts for BCI applications. In paper, we collect RSVP-based electroencephalogram (EEG) dataset, which includes 11 subjects. The experimental task image retrieval. Also,...
Assessment is an important prerequisite for the intervention of children with autism. The traditional approach has a high dependence on assessor's expertise and experience, susceptible to some subjective factors. Due lack experienced assessors, it necessary investigate alternatives assess autism properly. Computer games have great potentials assessment autism, which provide objective results by collecting analyzing game data. However, validity reliability based computer still need be...
Difficulty with implicit learning plays an important role in the symptomology of autism spectrum disorder (ASD). However, findings motor are inconsistent. This study evaluated sequence and its relationship ability children without ASD. We adopted a classic serial reaction time task retention three awareness tests. The Movement Assessment Battery for Children was administered to assess children's ability. Significant differences between ASD were only found but not immediately after task....
This study investigated the outcomes of using a consultant workshop model to help implement performance management (PM) methods in selected Chinese autism agencies. A need for improvement educational services agencies was identified. However, theory and organizational behavior (OBM) general PM particular are still foreign community. The primary research question current whether first-line teacher could be improved by use train staff system. Four different provinces participated this study....
This article was originally published in Proteomics 2010, 10 , 90–98, DOI 10.1002/pmic.200900513
Elagolix sodium (ELS) is a marketed product using to release moderate severe endometriosis-associated pain. It contains functional groups such as carboxyl group, secondary amino 2,4-dioxo pyrimidinyl and several benzyl or benzyl-like position hydrogen atom that are susceptive occur stress degradation. Forced degradation studies of ELS revealed different profiles under photo, thermal, acidic, neutral, alkaline peroxide oxidative conditions. With structural elucidation LC-PDA/UV-MSn NMR, the...
Emotion is the psychological and physiological response of human to external things, occupies an important place in study human-computer interaction. Electroencephalogram (EEG) a signal that widely used field emotion awareness recognition. EEG signals can be divided into 5 basic rhythms according frequency, most existing research on recognition based directly processes extracts corresponding features. This method easy lose rhythm information cannot give full play its function. Therefore,...
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Mental workload level can reflect subjects' personal ability. In addition, continuous high of mental reduce performance level, so it is necessary to detect in the time. this paper, we propose a CNN model for time-frequency analysis based on Siamese networks (Siamese-EEGNet), which original Electroencephalogram (EEG) signal and Power Spectral Density (PSD) are used as inputs, features extracted layer by through convolutional layers. Using P3 measure, pretrained large volume data set using...