A5009057401- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Birth, Development, and Health
- Statistical Methods in Clinical Trials
- Pregnancy and preeclampsia studies
- Aortic Disease and Treatment Approaches
- Cardiac Imaging and Diagnostics
- Cystic Fibrosis Research Advances
- Climate Change and Health Impacts
- Renal Diseases and Glomerulopathies
- Parasites and Host Interactions
- Advanced Statistical Process Monitoring
- Childhood Cancer Survivors' Quality of Life
- Parasite Biology and Host Interactions
- Pharmaceutical Economics and Policy
- Diabetes and associated disorders
- Heart Rate Variability and Autonomic Control
- Healthcare cost, quality, practices
- Antimicrobial Resistance in Staphylococcus
- Obesity, Physical Activity, Diet
- Heart Failure Treatment and Management
- Cardiovascular Health and Disease Prevention
- Statistical Methods and Inference
Charles University
2011-2025
Karlovac University of Applied Sciences
2024
Istituto di Matematica Applicata e Tecnologie Informatiche
2023
University Hospital in Motol
2015
University of Washington
1995-2003
Cancer Research And Biostatistics
1999
Background —Patterns of temporal variation cardiac arrests may be important for understanding mechanisms leading to the onset acute cardiovascular disorders. Previous studies reported diurnal arrests, with high incidence in morning and evening, lack daily during week, some seasonal variation. The association between time day recurrent has not been previously examined. Methods Results —We explored 6603 out-of-hospital attended by Seattle Fire Department. data exhibit variation, a low at night...
Abstract There has been much debate about the appropriateness of over-the-counter (OTC) cough and common cold medications (CCM). The aim this nationwide study was to analyse incidence CCM intoxications in Czech paediatric population from 2014 2023. We performed a retrospective on (ages 0–18 years) were 7,056 cases intoxication children, which 6,406 resulted unintentional intoxication. No lethal doses reported, but there 1,769 documented toxic doses. Unintentional represented 15.60% all...
In designing a sequential monitoring plan for the AVID (Antiarrhythmics Versus Implantable Defibrillators) study, multi-centred clinical trial, we completed simulation study to help ourselves and Data Safety Monitoring Board understand implications of various plans. particular, compared three test statistics use functions. Simulation was based on approximate trial parameters two plausible but distinct alternative hypotheses. The power detect difference between treatment arms computed as...
Abstract Background Several previous studies have reported a more severe course of nephrotic syndrome in children with low birth weight. Patients Cohort 223 idiopathic syndrome. Methods We aimed to investigate the association between and Data from seven paediatric nephrology centres were used. Results Children weight had 3.84 times higher odds for steroid-sensitive (95% CI 1.20–17.22, P=0.041), those remission after 7 days much disease (OR 8.7). Low longer time (median 12 vs. 10 days,...
This prospective study evaluated the relationship between echocardiography parameters of left ventricular (LV) diastolic function and mild-to-moderate renal impairment in 82 patients with type 2 diabetes mellitus. The mean age was 61.1 years. A significant correlation found estimated glomerular filtration rate (eGFR) ratio peak velocity early transmitral flow (E) to mitral annular motion (E′). Cluster analysis revealed two subgroups different E′ values but comparable eGFRs. eGFR E/E′ 38 ≤...
Type 1 diabetes (T1D) in children and adolescents is relatively often accompanied by other immunopathological diseases, autoimmune thyroid disease (AITD) or celiac (CD). Our aim was to assess whether these conditions are associated with changes the health-related quality of life (HRQOL) pediatric patients T1D. In a cross-sectional study we identified eligible 332 T1D aged 8-18 years, whom 248 (75%) together their parents responded PedsQL Generic Diabetes Modules. Compared 143 without...
The nasal avian schistosome Trichobilharzia regenti spends part of its intravertebrate period life within the central nervous system. Migration parasites can be accompanied by neuromotor disorders or paralysis in natural definitive hosts (ducks) and even laboratory mammals. Cercariae are also able to penetrate human skin induce cercarial dermatitis. While cellular antibody responses against cercariae migrating schistosomula have been investigated mice, little is known about immune reactions...
OBJECTIVE: To evaluate whether plasma adrenomedullin is involved in the previously reported significant inverse correlation between left ventricular (LV) end-diastolic pressure (peak velocity of early transmitral flow/peak diastolic mitral annular motion ratio [E/E′]) and estimated glomerular filtration rate (eGFR) patients with type 2 diabetes mellitus, mild-to-moderate renal function impairment LV relaxation (E′ ≤ 7.1 cm/s). METHODS: Plasma concentration, E/E′ eGFR were assessed 82...
We show by simulation and numerical integration techniques that power is largely unaffected play the winner strategies in a typical chronic disease mortality trial utilizing logrank test. This raises issue of ethics equal allocation such setting.
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Hájek P, Polaková E, Adlová R, et al. Mid-term outcomes of patients with Lotus and Evolut transcatheter valves. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2022;18(2):146-153. doi:10.5114/aic.2022.118531. APA Hájek, P., Polaková, E., Adlová, R., Horváth, M., Hansvenclová, & Pecková, M. (2022). Interwencyjnej, 18(2), 146-153. https://doi.org/10.5114/aic.2022.118531 Chicago Petr,...
Abstract Background Low birth weight (LBW) is associated with cardiovascular diseases (CVD); however, the roles of specific clinical and biochemical attributes remain unknown. Methods In this two-center study, we investigated risk factors (RFs) for development CVD among 5-year-old LBW children. The assessed RFs were low-density lipoprotein (LDL), high-density (HDL), triglyceride (TG) levels; urine protein/creatinine ratio (PCR); masked hypertension (HT); non-dipping blood pressure (BP)....
Abstract Background Many studies have demonstrated the association between low birth weight (LBW) and chronic kidney disease, estimated glomerular filtration rate (eGFR) volume (KV). However, on twins those investigating numerous perinatal factors beyond LBW, their associations with various parameters are scarce. Methods A two-center cross-sectional study five-year-old LBW children was conducted 2021 2023. 110 were enrolled (8 58 very (VLBW), 44 extremely (ELBW)); 56 twins. We examined (BW),...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Chabová B, Hájek P, Adlová R, Hansvenclová E, Pecková M, Veselka J. The impact of education as a marker socio-economic status on survival patients after transcatheter aortic valve implantation. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2022;18(1):50-57. doi:10.5114/aic.2022.115307. APA Chabová, B., Hájek, P., Adlová, R., Hansvenclová, E., Pecková, M., & Veselka, (2022)....
Objectives: To evaluate the association of diastolic function left ventricle with flowme-diated dilatation (FMD) in uncomplicated Type 2 diabetes mellitus patients. Methods: Eighty-two diabetic patients were examined by pulse and tissue Doppler echocardiography FMD brachial artery. The divided into groups according to size ventricular relaxation parameter—E’. Results: average age was 61 ± 6 years. 5.0 1.8% 41 E’ from 3 7.4 cm/s (mean cm/s) comparing 5.1 1.9% (p = 0.96) 7.5 10.9 8.9 cm/s)....
Abstract Introduction Use of the mechanically expandable transcatheter aortic valve (MEV) has been recently linked to increased risks dysfunction and cardiovascular mortality. The risk developing conduction disturbance with MEV is well-known, negative prognostic impact permanent pacemaker implantation (PPI) after (TAVI) another consideration. Aim This study aimed compare mid-term survival patients self-expandable valves (SEV), examine both groups according presence or absence PPI. Methods...
Use of the mechanically expandable transcatheter aortic valve (MEV) has been recently linked to increased risks dysfunction and cardiovascular mortality. The risk developing conduction disturbance with MEV is well known, negative prognostic impact permanent pacemaker implantation (PPI) after another consideration.This study aimed compare mid-term survival patients self-expandable valves (SEV), examine both groups according presence or absence PPI.This single-centre, retrospective,...
We show by simulation and numerical integration techniques that power is largely unaffected play the winner strategies in a typical chronic disease mortality trial utilizing logrank test. This raises issue of ethics equal allocation such setting.