A5075981213- Cholinesterase and Neurodegenerative Diseases
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Medicinal Plants and Neuroprotection
- Essential Oils and Antimicrobial Activity
- S100 Proteins and Annexins
- Retinoids in leukemia and cellular processes
- Liver Diseases and Immunity
- Nigella sativa pharmacological applications
- Nitric Oxide and Endothelin Effects
- Blood Coagulation and Thrombosis Mechanisms
- Advanced Glycation End Products research
- Venous Thromboembolism Diagnosis and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Vitamin C and Antioxidants Research
Mutah University
2023-2025
Jordan University of Science and Technology
2014
Alzheimer's disease is regarded as a common neurodegenerative that may lead to dementia and the loss of memory. We report here nootropic anti-amnesic effects both peppermint rosemary oils using rat model scopolamine-induced amnesia-like AD. Rats were administered orally with two doses (50 100 mg/kg) each single oil combined oils. The positive group used donepezil (1 mg/kg). In therapeutic phase, rats scopolamine through oral administration During showed significant (p < 0.05) decrease in...
The epigenetic silencing of tumor suppressor genes (TSGs) is critical in the development chronic myeloid leukemia (CML). SHP-1 functions as a TSG and negatively regulates JAK/STAT signaling. Enhancement expression by demethylation provides molecular targets for treatment various cancers. Thymoquinone (TQ), constituent Nigella sativa seeds, has shown anti-cancer activities However, TQs effect on methylation not fully clear. Therefore, aim this study to assess ability enhance through modifying...
Oxidative stress is characterized by excessive production of various free radicals and reactive species among which, peroxynitrite most frequently produced in several pathological conditions. Peroxynitrite the product superoxide anion reaction with nitric oxide, which reported to take place intravascular compartment. Several studies have that targets red blood cells, platelets plasma proteins, induces forms oxidative damage. This vitro study was designed further characterize types damage...
Hydrogen peroxide (H2O2) is reactive oxygen species produced by cellular metabolism in human body. This vitro study was designed to measure oxidative injury induced clotting factors and plasma proteins H2O2 determined the capability of Gallic acid protect against H2O2-induced injury. The resist oxidation estimated measuring prothrombin time (PT), activated partial thromboplastin (aPTT), protein carbonyl malondialdehyde formation experimental groups. Incubation with 0.5% for 30 minutes...