A5101898727- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- Food composition and properties
- Nuts composition and effects
- Agriculture Sustainability and Environmental Impact
- Nanoparticle-Based Drug Delivery
- Nanopore and Nanochannel Transport Studies
- Gold and Silver Nanoparticles Synthesis and Applications
- Botanical Research and Chemistry
- Meat and Animal Product Quality
- Electrospun Nanofibers in Biomedical Applications
- Muscle metabolism and nutrition
- Chemical Synthesis and Analysis
Advanced Center for Chronic Diseases
2018
University of Chile
2018
Universidad Andrés Bello
2018
Here we report the incorporation of gold nanostructures (nanospheres or nanorods, functionalized with carboxylate-end PEG) and curcumin oil-in-water (O/W) nanoemulsions (CurNem) into alginate microgels using dripping technique. While are promising nanomaterials for photothermal therapy applications, CurNem possess important pharmacological activities as reported here. In this sense, evaluated effect on cell viability both cancerous non-cancerous lines (AGS HEK293T, respectively),...
Perinatal asphyxia interferes with neonatal development, resulting in long-term deficits associated systemic and neurological diseases. Despite the important role of poly (ADP-ribose) polymerase 1 (PARP-1) regulation gene expression DNA repair, overactivation PARP-1 asphyxia-exposed animals worsens ATP-dependent energetic crisis. Inhibition offers a therapeutic strategy for diminishing effects perinatal asphyxia.We designed nanosystem that incorporates specific siRNA knockdown. The was...
Low effectiveness and resistance to treatments are commonplace in disorders of the central nervous system (CNS). These issues concern mainly blood-brain barrier (BBB), which preserves homeostasis brain protects this organ from toxic molecules biohazards by regulating transport through it. BBB shuttles-short peptides able cross BBB-are being developed help therapeutics barrier. shuttles can be discovered massive exploration chemical diversity (e.g. computational means, phage display) or...