A5024962501- Schizophrenia research and treatment
- Mental Health Treatment and Access
- Psychiatric care and mental health services
- Health disparities and outcomes
- Bipolar Disorder and Treatment
- Cardiac Health and Mental Health
- Chronic Disease Management Strategies
- Healthcare Decision-Making and Restraints
- Suicide and Self-Harm Studies
- Mental Health and Patient Involvement
- Grief, Bereavement, and Mental Health
- Health, psychology, and well-being
- Mental Health and Psychiatry
- Emergency and Acute Care Studies
- Diabetes Management and Education
- Maternal Mental Health During Pregnancy and Postpartum
- Migration, Health and Trauma
- Homelessness and Social Issues
- Health Policy Implementation Science
- Adolescent and Pediatric Healthcare
- Homicide, Infanticide, and Child Abuse
- Child and Adolescent Psychosocial and Emotional Development
- Health Systems, Economic Evaluations, Quality of Life
- Primary Care and Health Outcomes
- Diabetes Management and Research
University College London
2016-2025
Camden and Islington NHS Foundation Trust
2016-2025
North East London NHS Foundation Trust
2024-2025
St Pancras Hospital
2016-2025
Faculty (United Kingdom)
2015-2024
University of London
2003-2024
Queen Mary University of London
2024
Chinese University of Hong Kong
2024
University of Hong Kong
2024
Universidad de Granada
2023
People with severe mental illness (SMI) appear to have an elevated risk of death from cardiovascular disease, but results regarding cancer mortality are conflicting.To estimate this excess and the contribution antipsychotic medication, smoking, social deprivation.Retrospective cohort study.United Kingdom's General Practice Research Database. Patients Two cohorts were compared: people SMI diagnoses without such diagnoses. Main Outcome Measure Mortality rates for coronary heart disease (CHD),...
Bipolar disorder and schizophrenia are associated with increased mortality relative to the general population. There is an international emphasis on decreasing this excess mortality.
<b>Objectives</b> To describe the incidence of recorded mental illness and challenging behaviour in people with intellectual disability UK primary care to explore prescription psychotropic drugs this group. <b>Design</b> Cohort study. <b>Setting</b> 571 general practices contributing data The Health Improvement Network clinical database. <b>Participants</b> 33 016 adults (58% male) who contributed 211 793 person years’ data. <b>Main outcome measures</b> Existing new records illness,...
Excess deaths from cardiovascular disease are a major contributor to the significant reduction in life expectancy experienced by people with schizophrenia. Important risk factors this smoking, alcohol misuse, excessive weight gain and diabetes. Weight also reinforces service users' negative views of themselves is factor poor adherence treatment. Monitoring relevant physical health frequently inadequate, as provision interventions modify these. These guidelines review issues surrounding...
Domestic and sexual violence are significant public health problems but little is known about the extent to which men women with severe mental illness (SMI) at risk compared general population. We aimed compare prevalence impact of against SMI patients population.Three hundred three randomly recruited psychiatric patients, in contact community services for ⩾ 1 year, were interviewed using British Crime Survey domestic/sexual questionnaire. Prevalence correlates this sample those from 22 606...
BackgroundIdentifying modifiable risk factors is essential to reduce the prevalence adolescent depression. Self-report data suggest that physical activity and sedentary behaviour might be associated with depressive symptoms in adolescents. We examined associations between objectively measured adolescents.MethodsFrom a population-based cohort of adolescents whose mothers were invited participate Avon Longitudinal Study Parents Children (ALSPAC) study, we included participants at least one...
<b>Objectives</b> To evaluate the clinical effectiveness of group art therapy for people with schizophrenia and to test whether any benefits exceed those an active control treatment. <b>Design</b> Three arm, rater blinded, pragmatic, randomised controlled trial. <b>Setting</b> Secondary care services across 15 sites in United Kingdom. <b>Participants</b> 417 aged 18 or over, who had a diagnosis provided written informed consent take part study. <b>Interventions</b> Participants, stratified...
Objectives US and UK suicide prevention strategies suggest that bereavement by the of a relative or friend is risk factor for suicide. However, evidence lacking exceeds any sudden bereavement, specific to suicide, applies peer We conducted first controlled UK-wide study test hypothesis young adults bereaved have an increased suicidal ideation attempt compared with other deaths. Design National cross-sectional study. Setting Staff students at 37 higher educational institutions in 2010....
Abstract Purpose The COVID-19 pandemic has potential to disrupt and burden the mental health care system, magnify inequalities experienced by service users. Methods We investigated staff reports regarding impact of in its early weeks on users UK using a mixed methods online survey. Recruitment channels included professional associations networks, charities, social media. Quantitative findings were reported with descriptive statistics, content analysis conducted for qualitative data. Results...
The importance of incorporating Natural Language Processing (NLP) methods in clinical informatics research has been increasingly recognized over the past years, and led to transformative advances. Typically, NLP systems are developed evaluated on word, sentence, or document level annotations that model specific attributes features, such as content (e.g., patient status, report type), section types current medications, medical history, discharge summary), named entities concepts diagnoses,...
People with severe mental illnesses such as schizophrenia are three times more likely to smoke than the wider population, contributing widening health inequalities. Smoking remains largest modifiable risk factor for this inequality, but people illness have not historically engaged smoking cessation services. We aimed test effectiveness of a combined behavioural and pharmacological intervention targeted specifically at illness.In (SCIMITAR+) trial, pragmatic, randomised controlled study, we...
Results of most research on the physical health people with mental illness suggests morbidity and mortality from certain conditions is high in long-term illnesses. In this review, I examine psychiatric patients, especially those schizophrenia or depression some possible explanations for any inequities their status. also discuss care that patients receive, both terms recognition subsequent intervention, particular reference to cardiovascular disease. Finally, review potential barriers...
<h3>Objective</h3> To examine the recorded indication for antipsychotic prescriptions in UK primary care. <h3>Design</h3> Cohort study. <h3>Setting</h3> Primary <h3>Participants</h3> Individuals prescribed antipsychotics between 2007 and 2011. <h3>Measures</h3> The proportion of individuals with a diagnosis (1) psychosis bipolar disorder, (2) other diagnoses including depression, anxiety dementia (3) none these diagnoses. <h3>Results</h3> We identified 47 724 agents. 13 941 received...
To examine whether the 1-year prevalence of major depressive disorder (MDD), generalized anxiety (GAD), and their comorbidity were associated with subsequent all-cause cardiovascular disease (CVD) mortality during 15 years in Vietnam veterans.Participants (N = 4256) from Experience Study. Service, sociodemographic, health data collected service files, telephone interviews, a medical examination. One-year MDD GAD was determined through diagnostic interview schedule based on Diagnostic...
Background Depression is associated with coronary heart disease and stroke, but associations a range of pathologically diverse cardiovascular diseases are not well understood. We examine the risk 12 according to depression status (history or new onset). Methods Cohort study 1,937,360 adult men women, free from at baseline, using linked UK electronic health records between 1997 2010. The exposures were new-onset (a GP diagnosis and/or prescription for antidepressants during one-year...
People with severe mental illness (SMI), including schizophrenia and bipolar disorder, have excess rates of cardiovascular disease (CVD). Risk prediction models validated for the general population may not accurately estimate risk in this group.To develop validate a model exclusive to predicting CVD events people SMI incorporating established factors additional variables.We used anonymous/deidentified data collected between January 1, 1995, December 31, 2010, from Health Improvement Network...
BackgroundHigh resource expenditure on acute care is a challenge for mental health services aiming to focus supporting recovery, and relapse after an crisis episode common. Some evidence supports self-management interventions prevent such relapses, but their effect readmissions following untested. We tested whether intervention facilitated by peer support workers could reduce rates of readmission people discharged from resolution teams, which provide intensive home treatment crisis.MethodsWe...