(1) Background: Methylmercury (MeHg) exposure during pregnancy is an important issue due to its possible adverse health effects on fetus. To contribute the development of assessment system Hg through fish consumption and children, we examined hair levels in pregnant women birth weight length. (2) Methods: In 2018, a cohort study was conducted 118 women-infant pairs from six community centers northern coastal area Central Java Indonesia. Data mothers’ characteristics pregnancy, outcomes, were...

Vascular spasm is a well-known complication during vascular surgery. Topical lidocaine frequently used to prevent this spasm. However, the effects of on endothelium-dependent antiaggregation are not clear.The aggregation platelet-rich plasma (PRP) obtained from healthy volunteers was measured by turbidimetric technique at 37 degrees C. (1) Cultured porcine aortic endothelial cells were preincubated with (3.7 microM mM), NG-methyl-L-arginine (300 microM), or indomethacin (10 microM) for 30...

Introduction: sexual and reproductive rights in individuals with intellectual disabilities (ID), particularly developing countries, are often neglected. Although affected never complained, the problems were found augmented from families. Over last two decades, parents professionals acknowledged right try to accommodate these needs. Indonesia, a country strong religious culture beliefs may has different perspectives on attitudes towards sexuality ID which respect family. The aimed of this...

Background: Besides seizure control, quality of life (QoL) should be considered as an equally important outcome for epilepsy surgery service providers. The paucity QoL reports from developing countries has enlarged the representation gap between wealthy and with fewer resources. In this study, we evaluated postoperative in Indonesian drug-resistant cohort where faces limited resource availability. Methods: We patients temporal lobe who underwent our center Semarang, Indonesia, 2001 until...

Background:  The aim of epilepsy surgery is to improve the quality life people with epilepsy. Temporal lobe (TLE) most common form intractable a risk low due uncontrolled seizures. In this study, we evaluated among TLE patients who underwent amygdalohippocampectomy between those were free from seizure and not.Methods: This was cross-sectional observational study. postoperative measured by QOLIE-31 questionnaire followed-up at least 12 months since surgery. Results: Among 31 patients, 21...

Background: Coronary collateral circulation (CCC) is linked to myocardial remodeling severity in patients with chronic ischaemic heart disease (IHD). However its effect on left ventricular reverse (LVRR) IHD underwent coronary artery bypass surgery (CABG) has never been reported. Purpose of this study was investigate the CCC grade LVRR event CABG.
 Methods: This prospective cohort performed CABG. The classified using Rentrop score, i.e low (Rentrop score 0 and 1) high 2 3). defined as a...

Breast cancer incident continues to increase globally. The surgical management can be combined with other therapeutic modalities, including chemotherapy, radiation, and immunotherapy, such as Artemisia vulgaris (AV). This study aimed determine the effect of AV extract on Granzyme expression tumor mass diameter growth C3H mice adenocarcinoma mammae. Twenty-four female were randomly divided into groups K (control), P1 (AC chemotherapy), P2 (AV extract), P3 (combination). Adenocarcinoma mammae...

BACKGROUND: Aromatase inhibitor therapy is commonly used for breast cancer patients with characteristics of positive estrogen and progesterone receptors test without metastases. Thus, this kind generally gives side effects aromatase-induced arthralgia (AIA). Moringa oleifera has a strong anti-inflammatory substance that the potential to reduce inflammation pain in patient AIA. AIM: This study aims assess effect M. extract administration on response inflammatory status aromatase...

Introduction: There is an increasing number of suicides in Indonesia. A high risk suicide often associated with borderline personality disorder (BPD). To address this issue, dialectical behavior therapy (DBT) has been specifically designed for patients frequent suicidal and BPD. This study aims to develop DBT skills modules Indonesian language groups implement clinical practice.Methods: research was conducted three stages. Stage 1 involved preparing the module 13 weeks, including adding TIPP...

Background: Fragile X syndrome (FXS) is the most common cause of inherited intellectual disability and it associated with autism spectrum disorders. Abnormal neurological symptoms are believed due to lack fragile mental retardation protein (FMRP). By understanding role FMRP in brain, some therapeutic approaches have been tried hope reduce or prevent FXS symptoms. In Indonesia, a number children diagnosed treated as developmentally disabled child without etiologic diagnosis FXS. None them get...

Event Abstract Back to Association of hair total mercury with serum ferritin level among Indonesian pregnant woman: a preliminary study Muflihatul Muniroh1*, Saekhol Bakri2, Ainun R. Gumay1, Julian Dewantiningrum3, Mulyono Mulyono3 and Hardian Hardian1 1 Department Physiology, Faculty Medicine Diponegoro University, Indonesia 2 Departement Public Health, 3 Pediatrics, Background The exposure Hg in women is an important issue since it can pass the placental blood barrier affect fetus. This...

Event Abstract Back to Effects of Carica pubescens leaf extract on haematological profile and histopathological appearance azoxymethane-induced colon cancer rats Ainun R. Gumay1*, Saekhol Bakri1, Eka M. Sugeng1, Maharani S. Yudina1, Faradilla N. Bleizensky1, Muflihatul Muniroh1, Yosef Purwoko1 Hardian Hardian1 1 Diponegoro University, Indonesia ABSTRACT Background Neuroinflammatory apoptosis mechanisms play an important role in the pathogenesis colorectal cancer. (CP) has potential...

Event Abstract Back to The effect of autonomous sensory meridian response stimulation on sleep quality Sari S. Febriani1, Hardian Hardian1* and Tanjung A. Sumekar1 1 Diponegoro University, Indonesia Background Sleep is time for brain recover biochemistry physiologic function the after standby during day time. Stress may cause sleeping disturbance reduce quality. Stimulus Autonomous Sensory Meridian Response (ASMR) can create a feeling relaxation comfort that helps one fall asleep. aim this...

Event Abstract Back to The effect of Som Jawa (Talinum triangulare) on BALB/c mice swimming time Hardian Hardian1*, Yosef Purwoko1, Ainun R. Gumay1, Muflihatul Muniroh1, Darmawati A. Indraswari1 and Armita Apsari1 1 Diponegoro University, Indonesia Background is a plant commonly found in Central Java that has been believed potency as Korean Ginseng. aim the study investigate parameter physical endurance. Method Study design was pre-post test parallel groups design. Samples were male, 3...

Event Abstract Back to Anti-inflammatory effect of celery squeezed juice on carrageenan induced rat paw edema Syarief Hudaya1* and Hardian Hardian2 1 Universitas Wahid Hasyim, Indonesia 2 Diponegoro University, Background Celery (Apium graveolens L.) contains several active compounds with some anti-inflammatory activities. The is commonly used in the community treat various diseases including inflammation. aim this study determine squeeze acute Methods design was two-groups pre- post-test...

Event Abstract Back to Association of sulfur exposure attention deficit among potato farmers in volcanic area Dieng, Central Java, Indonesia Saekhol Bakri1*, Ainun R. Gumay1, Erni Erni1, Muflihatul Muniroh1 and Hardian Hardian1 1 Diponegoro University, Background Volcanoes their eruptions can result many health impacts, which is an unconscious danger for community living nearby the area. Chronic may cause problem especially nervous system respiratory diseases. The aim this study investigate...

Event Abstract Back to Effects of Morinda citrifolia on Diabetic-Induced Renal Tissue Apoptosis Indranila K. Samsuria1* and Hardian Hardian1 1 Diponegoro University, Indonesia Background Diabetic nephropathy (DN) is a microvascular complication due chronic hyperglycemia. nephron cells are the major feature DN. The aim this study investigate effects (MC) apoptosis Methods Subjects were 30 male Sprague Dawley rats. All rats given streptozotocin (STZ) 40 mg/kg BW induce diabetes. randomly...

BACKGROUND Trinucleotide repeat expansion (TRE) diseases are genetic caused by an increase in the number of CAG, CGG, and CTG codons. CAG exon 1 androgen receptor (AR) gene is known to be associated with disorders sex development (DSD) spinal bulbar muscular atrophy (SBMA). Because traditional Southern blot for laborious time-consuming, this study was aimed use high-resolution melting (HRM) analysis screen length AR Indonesian patients DSD. METHODS In total, 30 male DSD (46, XY), one patient...

BACKGROUND: Enterocutaneous fistula is an abnormal connection between gastrointestinal tract with skin or wound and studies showed low numbers of spontaneous closure (20–30%) despite proper treatment nutrition high morbidity mortality rate in repair operation. Phenytoin, commonly used as anticonvulsant, has shown its effects on healing process such promoting fibroblast activities, formation granulation tissue, reduction collagenase increasing collagen production, other connective tissue...

Prevalensi gangguan psiko-afektif yang ditandai dengan gejala depresi dan kecemasan pada mereka berusia 15 tahun ke atas mencapai sekitar 6,1 dari total penduduk Indonesia. Salah satu pedoman untuk mengevaluasi penggunaan obat rasional adalah indeks Organisasi Kesehatan Dunia (WHO). Perlakuan tidak tepat dapat merugikan masyarakat, terutama bagi masyarakat menengah bawah. Penelitian ini bertujuan melakukan penelitian tentang pola peresepan pasien rawat jalan di poli jiwa Rumah Sakit Breves...

Background: Sexuality is an integral part of adult human life, including for individuals with a disability. Even though sexuality fundamental right however, person intellectual disability, expressing and exploring limited. This study aimed to determine the reliability validity ASQ-ID in Indonesian language.
 Methods: A cross-sectional observational designed adaptation validation Attitudes toward Questionnaire Intellectual Disability (ASQ-ID) version was conducted 2019. The subjects were...