Mouhannad M. Sadek

ORCID: 0000-0003-2526-9359
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About
Contact & Profiles
Research Areas
  • Cardiac Arrhythmias and Treatments
  • Atrial Fibrillation Management and Outcomes
  • Cardiac pacing and defibrillation studies
  • Cardiac electrophysiology and arrhythmias
  • Cardiac Structural Anomalies and Repair
  • Cardiac Valve Diseases and Treatments
  • Cardiovascular Syncope and Autonomic Disorders
  • Cardiac Imaging and Diagnostics
  • Cardiovascular Effects of Exercise
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Sarcoidosis and Beryllium Toxicity Research
  • Advanced MRI Techniques and Applications
  • Occupational exposure and asthma
  • Mechanical Circulatory Support Devices
  • Neurological disorders and treatments
  • Cardiovascular Function and Risk Factors
  • ECG Monitoring and Analysis
  • Viral Infections and Immunology Research
  • Radiation Dose and Imaging
  • Central Venous Catheters and Hemodialysis
  • Venous Thromboembolism Diagnosis and Management
  • Phonocardiography and Auscultation Techniques
  • Neonatal Health and Biochemistry
  • Cardiac tumors and thrombi
  • Silk-based biomaterials and applications

Badr University in Cairo
2025

Southlake Regional Health Center
2022-2025

Benha University
2024

Ottawa Heart Institute
2024

University of Ottawa
2013-2023

University of Toronto
2008-2023

Canadian Rheumatology Association
2023

Suez Canal University
2022

Ottawa Hospital
2015-2021

Ain Shams University
2017

Left ventricular (LV) scar on late gadolinium enhancement (LGE) cardiac magnetic resonance has been correlated with life-threatening arrhythmic events in patients apparently idiopathic arrhythmias (VAs). We investigated the prognostic significance of a specific LV-LGE phenotype characterized by ringlike pattern fibrosis.A total 686 nonsustained VA underwent contrast-enhanced resonance. A LV was defined as subepicardial/midmyocardial LGE involving at least 3 contiguous segments same...

10.1161/circulationaha.120.047640 article EN Circulation 2021-01-06

Implantable cardioverter defibrillators (ICDs) improve survival in patients at risk for cardiac arrest, but are associated with intravascular lead-related complications. The subcutaneous ICD (S-ICD), no components, was developed to minimize complications.To assess key performance measures related delivery of therapy, including inappropriate shocks (delivered absence life-threatening arrhythmia) and failed (which did not terminate ventricular arrhythmia).Randomized, multicenter trial....

10.7326/m22-1566 article EN Annals of Internal Medicine 2022-11-07

The optimal approach to repeat catheter ablation for recurrent paroxysmal atrial fibrillation (PAF) is unknown. Consecutive patients undergoing PAF were studied. A six-step was used in all cases: re-isolation of reconnected pulmonary veins (PVs), left low voltage areas (LVAs), targeted clinical or inducible flutter/tachycardia, non-PV trigger ablation, supraventricular tachycardia, and additional empiric based on operator judgment. primary study outcome arrhythmia-free survival at 1-year....

10.1016/j.cjca.2025.02.033 article EN cc-by-nc-nd Canadian Journal of Cardiology 2025-03-01

Ablation of outflow tract ventricular arrhythmias may be limited by a deep intramural location the arrhythmogenic source. This study evaluates acute and long-term outcomes patients undergoing ablation premature complexes (PVCs).This multicenter series included with structurally normal heart or nonischemic cardiomyopathy PVCs defined by: (a) ≥ 2 following criteria: (1) earliest endocardial epicardial activation < 20ms pre-QRS; (2) Similar in different chambers; (3) no/transient PVC...

10.1093/europace/euad100 article EN cc-by-nc EP Europace 2023-04-25

Abstract Background The effectiveness, safety, and pulmonary vein (PV) reconnection patterns of point‐by‐point high‐power, short‐duration (HPSD) ablation relative to conventional force‐time integral (FTI)‐guided strategies for atrial fibrillation (AF) are unknown. Objectives To compare 1‐year freedom from arrhythmia (AA), complication rates, procedural times, PV with HPSD AF versus an FTI‐guided low‐power, long‐duration (LPLD) strategy. Methods We compared consecutive patients undergoing a...

10.1111/jce.14989 article EN Journal of Cardiovascular Electrophysiology 2021-03-10

Abstract Introduction Fluoroscopy use during catheter ablation procedures increases the cumulative lifetime radiation exposure of patients and operators, potentially leading to a higher risk cancer radiation‐related injuries. Nonfluoroscopic (NFA) has been described for supraventricular tachycardia, typical atrial flutter, paroxysmal fibrillation (AF), outflow‐tract ventricular tachycardia (VT). Complete transition NFA more complex arrhythmias, including persistent AF, left (LA) structural...

10.1111/jce.13735 article EN Journal of Cardiovascular Electrophysiology 2018-09-11

Patients with inherited arrhythmia syndromes are at an increased risk of sudden cardiac death (SCD). Specialized clinics were founded to optimize management and prevention SCD in this population. However, the clinical effectiveness these has never been evaluated.Clinical outcome data patients referred a specialized clinic between 2005 2014 for possible primary electric syndrome or arrhythmogenic right ventricular cardiomyopathy analyzed. Of 720 evaluated, 278 received definite probable...

10.1161/circep.115.003440 article EN Circulation Arrhythmia and Electrophysiology 2016-01-01
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