A5059150079- Neonatal and fetal brain pathology
- Pediatric Pain Management Techniques
- Diversity and Career in Medicine
- Infant Development and Preterm Care
- Advanced Neuroimaging Techniques and Applications
- Child and Adolescent Health
- Global Health Workforce Issues
- Global Health and Surgery
- Innovations in Medical Education
- Cardiovascular Issues in Pregnancy
- Congenital Heart Disease Studies
- Maternal and fetal healthcare
- Maternal Mental Health During Pregnancy and Postpartum
- Phonocardiography and Auscultation Techniques
- Non-Invasive Vital Sign Monitoring
- Human Health and Disease
- COVID-19 Impact on Reproduction
- Grief, Bereavement, and Mental Health
- Neuroscience and Neuropharmacology Research
- Functional Brain Connectivity Studies
- Autoimmune Neurological Disorders and Treatments
- Hospital Admissions and Outcomes
- Primary Care and Health Outcomes
- Emergency and Acute Care Studies
- Maternal and Perinatal Health Interventions
University of Oxford
2017-2024
John Radcliffe Hospital
2021-2024
NIHR Imperial Biomedical Research Centre
2021
Imperial College London
2020-2021
Queen Charlotte's and Chelsea Hospital
2021
Wellcome Centre for Integrative Neuroimaging
2021
Imperial College Healthcare NHS Trust
2021
Northwick Park Hospital
2020
Science Oxford
2018
Parental involvement in neonatal comfort care is a core component of family-centred care. Yet, parents experience range positive and negative feelings when providing pain-relieving interventions for their infants. Parents infants who participated the touch trial ( Petal ), multicentre randomised controlled investigating impact gentle parental on pain, were asked to complete an anonymous survey. This survey aimed (1) explore parent-reported motivations deciding participate trial; (2)...
Understanding the neurophysiology underlying neonatal responses to noxious stimulation is central improving early life pain management. In this multimodal MRI study, we use resting-state and diffusion investigate inter-individual variability in noxious-stimulus evoked brain activity. We observe that cerebral haemodynamic experimental can be predicted from separately acquired activity (n = 18). Applying prediction model independent Developing Human Connectome Project data 215), identify...
Electroencephalography (EEG) can be used in neonates to measure brain activity changes that are evoked by noxious events, such as clinically required immunisations, cannulation and heel lancing for blood tests. EEG provides an alternative approach infer pain experience infants compared with more commonly behavioural physiological assessments. Establishing the generalisability construct validity of these measures will help corroborate use brain-derived outcomes evaluate efficacy new or...
Abstract Understanding the neurophysiology underlying pain perception in infants is central to improving early life management. In this multimodal MRI study, we use resting-state functional and white matter diffusion investigate individual variability infants’ noxious-evoked brain activity. an 18-infant nociception-paradigm dataset, show it possible predict cerebral haemodynamic responses experimental noxious stimulation using their activity across nine networks from a separate stimulus-free...
An Indian woman in her 40s without any medical or psychiatric history presented with a seizure. She had become uncharacteristically quiet before suddenly cackling and banging hands feet repeatedly. developed facial upper limb dystonic posturing including the extension of one arm. The
<h3>Aims</h3> Most trainee doctors will care for children regularly during their careers; some Paediatric specialist training, others in settings such as Emergency Medicine or General Practice. Consequently, paediatric teaching ought to be part of the broad-based delivered Foundation prepare them later specialisation. This study sought quantify paediatrics that is offered Year 1 (FY1) and 2 (FY2) UK. <h3>Methods</h3> A cross-sectional survey FY1/FY2 was conducted at end 2020-2021 academic...
<h3>Background</h3> Non-invasive, continuous monitoring of cardiac output (CO) could transform care sick neonates through earlier detection and improved targeted management cardiovascular compromise. Whole body electrical bioimpedance (WBEB) has been developed for non-invasive CO measurement but yet to be validated use in neonates. WBEB may have significant advantages over intermittent, operator-dependent echocardiography. <h3>Objectives</h3> This study aimed validate (NICaS monitor, NI...
Abstract Understanding the neurophysiology underlying neonatal responses to noxious stimulation is central improving early life pain management. In this multimodal MRI study, we use resting-state and diffusion investigate inter-individual variability in noxious-stimulus evoked brain activity. We observe that cerebral haemodynamic experimental can be predicted from separately acquired activity (n=18). Applying prediction model independent Developing Human Connectome Project data (n=215),...
Background Most doctors will care for children regularly during their careers in settings such as the emergency department, general practice, surgery, or, a minority, paediatric specialist training. As such, exposure to topics related child health ought be part of broad curriculum learning offered UK Foundation Programme doctors. Objective This study aimed quantify teaching paediatrics that is accessed by Methods A cross-sectional electronic survey foundation year one or two (F1/F2) at end...
Medical elective placements in low- and middle-income countries (LMICs) provide a valuable opportunity for an insight into other cultures the workings of healthcare systems. Experiences o...
Abstract Understanding the neurophysiology underlying pain perception in infants is central to improving early life management. In this multimodal MRI study, we use resting-state functional and white matter diffusion investigate individual variability infants’ noxious-evoked brain activity. an 18-infant nociception-paradigm dataset, show it possible predict cerebral haemodynamic responses experimental noxious stimulation using their activity across nine networks from a separate stimulus-free...
<h3>Aims</h3> Paediatrics has recently struggled with recruitment compared to other specialties, and one of the lower competition ratios (2.09 886 applicants in 2021). Reasons for this include lack exposure potential paediatrics therefore reduced access mentorship; damaging stereotypes workload burnout specialty; structural barriers international graduates. Consequently, 2020-2021, UK Aspiring Paediatricians Society (UKAPS) launched a national scheme pairing current prospective...
<h3>Background</h3> Neonatal heart murmurs are commonly heard during routine newborn examination. In our institution, babies found to have a murmur on the postnatal ward reviewed in registrar-led clinic, ideally within 10 days. If persists, they referred for review an echocardiography clinic led by Neonatologist with Expertise Cardiology. We recently introduced paediatric echo technician pathway who is available perform two echocardiograms each week. <h3>Objectives</h3> sought assess safety...
<h3>Background</h3> Arterial stiffness is an independent predictor of cardiovascular morbidity and mortality in adults. structure function changes that increase arterial occur gradually over years but may be influenced by the perinatal environment. <h3>Objectives</h3> To systematically review literature to determine how environment impacts preadolescent children, following PRISMA guidelines. <h3>Methods</h3> PubMed was searched using terms: 'pulse wave velocity' (PWV), 'carotid intima-media...
Abstract Understanding the neurophysiology underlying neonatal responses to noxious stimulation is central improving early life pain management. In this multimodal MRI study, we use resting-state and diffusion investigate inter-individual variability in noxious-stimulus evoked brain activity. We observe that cerebral haemodynamic experimental can be predicted from separately acquired activity (n=18). Applying prediction model independent Developing Human Connectome Project data (n=215),...
Abstract Understanding the neurophysiology underlying neonatal responses to noxious stimulation is central improving early life pain management. In this multimodal MRI study, we use resting-state and diffusion investigate inter-individual variability in noxious-evoked brain activity. We demonstrate that cerebral haemodynamic experimental can be predicted from separately acquired activity (n=18). Applying prediction model independent Developing Human Connectome Project data (n=215), identify...