- Antifungal resistance and susceptibility
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Fungal Infections and Studies
- COVID-19 epidemiological studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Infectious Diseases and Mycology
- COVID-19 Pandemic Impacts
- SARS-CoV-2 detection and testing
- Vaccine Coverage and Hesitancy
- Respiratory Support and Mechanisms
- Medical and Biological Ozone Research
- Parasitic Diseases Research and Treatment
- Blood groups and transfusion
- Platelet Disorders and Treatments
- Thermal Regulation in Medicine
- Antibiotic Use and Resistance
- Pneumonia and Respiratory Infections
- Obesity, Physical Activity, Diet
- Gestational Diabetes Research and Management
- Pleural and Pulmonary Diseases
- COVID-19 and healthcare impacts
- Parasites and Host Interactions
- Nutrition and Health in Aging
All India Institute of Medical Sciences Raipur
2021-2025
All India Institute of Medical Sciences
2014-2025
All India Institute of Medical Sciences Bhopal
2021-2025
Leeds Teaching Hospitals NHS Trust
2024
West Suffolk NHS Foundation Trust
2024
Vivekananda Global University
2024
Poornima University
2024
Kyushu University
2024
National Council Of Educational Research And Training
2024
Employees' State Insurance Model Hospital
2023
ABSTRACT Background Post‐tuberculosis lung disease (PTLD) is a precursor to Aspergillus ‐related diseases. While Chronic Pulmonary Aspergillosis (CPA) has been extensively studied in the background of tuberculosis, Allergic Bronchopulmonary (ABPA) reported sporadically with limited information on its prevalence, clinical‐radiological features, and treatment outcomes. Objective This study, conducted high TB burden setting, aimed address this knowledge gap by systematically evaluating ABPA...
India imposed one of the world's strictest population-wide lockdowns on March 25, 2020 for COVID-19. We estimated epidemiological parameters, evaluated effect control measures epidemic in India, and explored strategies to exit lockdown. obtained patient-level data estimate delay from onset confirmation asymptomatic proportion. basic time-varying reproduction number (R0 Rt) after adjusting imported cases using incidence 4 April 2020. Using a SEIR-QDPA model, we simulated lockdown relaxation...
Abstract Background Chronic pulmonary aspergillosis (CPA) is known to complicate patients with post‐tubercular lung disease. However, some evidence suggests that CPA might co‐exist in newly‐diagnosed tuberculosis (P.TB) at diagnosis and also develop during therapy. The objective of this study was confirm the presence newly diagnosed P.TB baseline end‐of‐TB‐therapy. Materials Methods This prospective longitudinal included patients, followed up third month end‐of‐TB‐therapy symptom assessment,...
Abstract Introduction: Till date, no drug has shown definite benefit in non-severe COVID-19. Ivermectin is an antiparasitic which in-vitro efficacy reducing coronavirus-2 (SARS-CoV-2) load severe disease. Objectives: To determine if a single oral administration of to patients with mild and moderate COVID-19 effective converting SARS-CoV-2 RT-PCR negative result viral load. Methods: In this double-blind trial, were randomized elixir formulation 24 mg, 12 mg or placebo 1:1:1 ratio. The...
Background: The diagnosis of CPA relies on the detection IgG Aspergillus antibody, which is not freely available, especially in resource-poor settings. Point-of-care tests like LDBio ICT lateral flow assay, evaluated only a few studies, have shown promising results for CPA. However, no study has compared diagnostic performances LFA setting tuberculosis endemic countries and it with that Aspergillus. Objectives: This aimed to evaluate compare existing algorithm utilising ImmunoCAP Methods:...
Hypoxia in patients with COVID-19 is one of the strongest predictors mortality. Silent hypoxia characterised by presence without dyspnoea. has been shown to affect outcome previous studies.
Background: Leg cramps during pregnancy is a common discomfort characterized by involuntary,painful contraction of muscle groups that usually occur in the calf or small muscles foot but canaffect different part leg. The severity leg cramp pain variable and each attack may takefew minutes. 1 prevalence occurred among 30% to 50% pregnant women. Legcramping means painful spasm especially lower extremities occurs andmainly second half typically at night lasts for fewseconds 2 2Materials...
The TiO₂/SnO₂ thin films have garnered considerable attention for their application in optical devices due to superior transparency and stability. This study investigates the structural properties of prepared through electron beam (e-beam) evaporation. were annealed at 400°C one hour a muffle furnace evaluate influence annealing on properties. Characterization techniques, including X-ray diffraction (XRD), UV-Vis spectroscopy, atomic force microscopy (AFM), employed analyze films. XRD...
This study endeavours to comprehensively the spectrum of ENT manifestations in mild and asymptomatic COVID-19 observe natural course anosmia dysgeusia consequent SARS-Cov-2 infection. A prospective cohort was undertaken at a tertiary care centre India on admitted patients with RT-PCR proven COVID-19. Patients were included provided baseline National Early Warning Score (NEWS) less than 4. screened for using questionnaire baseline, 7 days, 14 days 28 days. 225 study. Of these complete data 4...
ABSTRACT Background The SARS-CoV-2 pandemic has quickly become an unprecedented global health threat. India with its unique challenges in fighting this pandemic, imposed one of the world’s strictest and largest population-wide lockdown on 25 March 2020. Here, we estimated key epidemiological parameters evaluated effect control measures COVID-19 epidemic India. Through a modelling approach, explored various strategies to exit lockdown. Methods We obtained data from 140 confirmed patients at...
Background: While long-term studies on the correlates of protection, vaccine effectiveness, and enhanced surveillance are awaited for SARS-CoV-2 vaccine, breakthrough infections help understand nature course this illness among vaccinated individuals guide in public health preparedness. This study aims to compare differences hospitalization outcomes infection fully with those unvaccinated partially individuals. Materials Methods: Single institution observational cohort study. compared...
Abstract Background Bronchoalveolar lavage (BAL) galactomannan (GM) is commonly used to diagnose Aspergillus ‐related lung diseases. However, unlike serum GM, which measured in undiluted blood, BAL‐GM estimated using variable aliquots and cumulative volume of instillates during bronchoscopy. Objective Since different studies have reported varying diagnostic accuracy cut‐offs for CPA, we hypothesized that the total instillate ‘order/label’ significantly affects values, was evaluated as part...
Enlargement of adipocyte is associated with their dysfunction and alterations in metabolic functions.We evaluated the association size subcutaneous omental adipose tissue body composition cardiovascular risk factors Asian Indians.Eighty (40 males 40 females) non-diabetic adult subjects undergoing elective abdominal surgery were included. Pre-surgery evaluation included anthropometric measurements, % fat by bioimpedance, area at L2-3 level (computed tomography) biochemical investigations...
Abstract Background- The sharp uptick in the cases of mucormycosis background COVID19 pandemic is a cause concern and reasons it’s impact remains to be seen. We studied clinical characteristics patients with co-infection performed literature review. Methods- This retrospective study was conducted at tertiary centre India. All admitted were included, details obtained from hospital records. did review literatures using terms “SARS-CoV2” OR “COVID19” AND “Mucormycosis” “co-infection” on Pubmed...
Mucormycosis isolated to the mandible is a rare presentation occurring generally after dental procedures. The case we report presented with discharging sinuses over facial region radiological appearance of osteomyelitis mandible. patient used apply an addictive powder his teeth leading caries. Following this, he pulled out all teeth, which probably led condition. Invasive sampling revealed mucormycosis. An extensive search for underlying immunodeficiency that had chronic granulomatous...
The "second wave" of the COVID-19 pandemic hit India from early April 2021 to June 2021. We describe clinical features, treatment trends, and baseline laboratory parameters a cohort patients with SARS-CoV-2 infection their association outcome.
This article reports that the annealing and hydrogenation effect on transmission, reflection bandgap of ZnSe/Mn ZnSe/Co diluted magnetic semiconductors (DMS).The semiconductor multilayers thin films were physically deposited by thermal evaporation technique at 10 -5 torr vacuum pressure onto glass substrates.To achieve inter-diffusion homogeneous structures, prepared samples annealed 473K for one hour in vacuum.Hydrogenation was done 20 30 psi H 2 to observe optical properties films.The...
Ongoing pandemic because of COVID-19 has spread across countries, with varied clinical features and severity. Awareness course among asymptomatic symptomatology in symptomatic cases is essential for patients' management as well optimal utilization health services (in resource limited settings) based on status risk factors. This study aimed to describe the characteristics outcomes patients admitted illness initial phase India.
Abstract Background Pulmonary aspergilloma (PA) is a common complication seen in patients with pulmonary tuberculosis sequelae. Antifungal therapy, including oral azoles, commonly used though only surgical resection offers curative benefit. Local administration of amphotericin B, like intracavitary instillation, has been effective nebulised B (nAB) never formally assessed. Objective The aim this prospective, non‐inferior, open‐label, randomised control trial to evaluate the efficacy and...