A5092468605- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Zebrafish Biomedical Research Applications
- Molecular Sensors and Ion Detection
- Nanoparticle-Based Drug Delivery
- Retinal Development and Disorders
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Protein Interaction Studies and Fluorescence Analysis
- Retinal Diseases and Treatments
- Cell death mechanisms and regulation
- Luminescence and Fluorescent Materials
- Corneal Surgery and Treatments
- Phagocytosis and Immune Regulation
Izmir University
2022-2024
Lusaka Apex Medical University
2024
Institute for Biomedicine
2024
Dokuz Eylül University
2022
V(III) instead of commonly used Fe(III) provided a rich tris-catechol-metal coordination at pH 7.4, which is important for slow drug release physiological pH. Bovine serum albumin (BSA) functionalized with catechol-containing dopamine (D) and cross-linked using tris-catechol-V(III) yielded pH-responsive compact D-BSA NPs (253 nm). However, conversion to bis- and/or mono-catechol-V(III) complexes in an acidic medium resulted degradation rapid doxorubicin (DOX). It was shown that entered...
Macular corneal dystrophy (MCD) is a rare congenital disease caused by mutations in the carbohydrate sulfotransferase 6 (chst6) gene. Patients suffer from opaque aggregates cornea leading to bilateral progressive vision loss 4th decade of life. Corneal transplantation only available treatment, which invasive, not every patient and recurrence symptoms common. Keratocytes express chst6 gene, encodes golgi enzyme that essential for sulfation keratan sulfate proteoglycans (KSPG). The KS leads...
The carbohydrate sulfotransferase 6 ( chst6 ) gene is linked to macular corneal dystrophy (MCD), a rare disease that leads bilateral blindness due the accumulation of opaque aggregates in stroma. encodes for keratan sulfate proteoglycan (KSPG) specific sulfotransferase. MCD patients lose sulfated KSPGs (cKS) cornea and serum. significance serum cKS loss has not been understood. Zebrafish structure similar humans it contains high levels Here, zebrafish shown be expressed head structures...