A5013470812- Organ and Tissue Transplantation Research
- Reconstructive Surgery and Microvascular Techniques
- Reconstructive Facial Surgery Techniques
- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
- Tracheal and airway disorders
- Orthopedic Surgery and Rehabilitation
- Facial Nerve Paralysis Treatment and Research
- Organ Donation and Transplantation
- Transplantation: Methods and Outcomes
- Organ Transplantation Techniques and Outcomes
- Lymphatic System and Diseases
- Mechanical Circulatory Support Devices
- Orthopedic Infections and Treatments
- Head and Neck Surgical Oncology
- Dysphagia Assessment and Management
- Bone fractures and treatments
- Facial Rejuvenation and Surgery Techniques
- Elbow and Forearm Trauma Treatment
- Digital Imaging in Medicine
- Social Media in Health Education
- Cardiac Ischemia and Reperfusion
- Telemedicine and Telehealth Implementation
- Facial Trauma and Fracture Management
- Surgical Sutures and Adhesives
Cleveland Clinic
2016-2025
Case Western Reserve University
2008-2025
University School
2016-2025
Cleveland Clinic Lerner College of Medicine
2016-2024
Istituto Nazionale di Fisica Nucleare, Sezione di Milano
2024
Creative Commons
2016-2023
Committee on Publication Ethics
2023
Campbell University
2023
American Society of Plastic Surgeons
2005-2022
Bridge University
2021
Maintenance of the blood supply to lymph nodes is necessary for survival and function. We report outcome vascularized node transfer with hilar perforators compared conventional technique.A total 21 patients affected by early stage II upper limb lymphedema were included in this study. Of them, 11 received a free groin flap containing nodes, 10 inguinal perforators. Mean follow-up was 46 40 months, respectively. Complications, secondary procedures, circumference limb, subjective symptomatology...
A number of authors have proposed retrograde arterial embolism as the responsible mechanism for filler-induced blindness. However, no previous human study has substantiated this mechanism. The aim was to investigate pathophysiology blindness using a fresh cadaver perfusion technique. head model that simulates both physiologic blood pressure and flow rate carotid artery, ophthalmic supratrochlear artery used. common cannulated internal jugular vein exposed open venous drainage. plasma-based...
Objective: The aim of this study was to evaluate a novel holographic craniofacial surgical planning application and its implementation throughout the operative stages facial transplantation by performing critical analysis comparative utility, cost, limitations MR 3D printing. Summary Background Data: Face is highly complex form reconstruction requiring significant planning, knowledge patient-specific spatial relationships, time-sensitive decision making. Computer-aided modeling has improved...
Excisional procedures have been successfully utilized by different authors in multistage treatment of upper extremity lymphedema. We used microsurgical principles perforator flap surgery order to develop a one-stage procedure that enables radical reduction the lymphedematous tissue with preservation vascular supply overlying skin.Between March 2000 and February 2007, 11 patients affected late stage II lymphedema underwent tissues perforators. Perforator vessels from radial posterior...
There are no established criteria for discontinuing ex vivo normothermic limb perfusion (EVNLP) before irreversible damage occurs. This study evaluates weight gain as an indicator of injury during EVNLP.Sixteen Yorkshire pig forelimbs were procured and preserved using EVNLP with a hemoglobin-based oxygen carrier (HBOC-201) or static cold storage. continued until termination met: arterial pressure ≥ 115 mm Hg, compartment > 30 20% reduction saturation. Limb weight, contractility,...
BACKGROUND: Utilization of peninsular buccal flaps for primary cleft palate repair is well-documented in the literature. However, there no report on application an island flap repair. This study aims to reveal clinical axial neurovascular propeller buccinator myomucosal flap. METHODS: An anatomical was performed by injection into pedicle twenty-two fresh hemifacial cadavers. Additionally, we analyzed palatal healing and outcomes twenty-five reconstructions utilizing thirty-six pedicled...
ABSTRACT Introduction The aim of this study was to evaluate ex vivo perfusion (EVP) for vascularized composite tissue preservation. We hypothesized that EVP could maintain allografts in near‐physiologic conditions ≥ 24 h. Methods Twenty superior epigastric artery perforator‐based abdominal flaps were procured from 10 Yorkshire pigs. Flaps preserved 12 h ( n = 5) or using with an oxygenated colloid solution containing HBOC‐201 oxygen carrier (HbO 2 Therapeutics, Souderton, PA). Contralateral...
Background: Ehlers-Danlos Syndromes comprise a heterogeneous group of connective tissue disorders, often associated with concerns about poor wound healing and elevated surgical complication rates. This study evaluated the safety elective plastic surgery in EDS patients relative to matched controls. We hypothesized that would not experience higher rates Methods: An IRB approved retrospective cohort controls who underwent between 2003 2023 was conducted at tertiary health care system. Patients...
Ischemia time represents a significant limitation for successful extremity transplantation because of the rapid deterioration ischemic muscle. Normothermic ex-situ preservation is an emergent method to prolong organ viability following procurement, by replicating physiologic conditions. The aim this study was develop normothermic limb perfusion system preserve and function porcine limbs 12 hours procurement.A total 18 swine were perfused. Thirteen used protocol. Five perfused according...
Abstract Ischemia and reperfusion injury remains a significant limiting factor for the successful revascularization of amputated extremities. Ex vivo normothermic perfusion is novel approach to prolong viability limbs by maintaining physiologic cellular metabolism. This study aimed evaluate outcomes extended ex limb (EVNLP) in preserving over 24 hours. A total 10 porcine forelimbs underwent EVNLP. Limbs were perfused using an oxygenated colloid solution at 38°C containing washed RBCs. Five...
Background. Ischemia-reperfusion injury remains a primary concern in upper extremity transplantation. Ex vivo normothermic perfusion (EVNP) enables near-physiological organ preservation, avoiding the deleterious effects of hypoxia and cooling. We investigated effectiveness human limb EVNP compared with static cold storage (SCS). Methods. Twenty extremities were procured. Ten perfused at 38 °C an oxygenated red blood cell–based solution, contralateral limbs served as SCS control (4 °C). was...
Background The use of topical immunosuppressants has been anecdotally reported for the treatment rejection in vascularized composite allotransplantation. aim this study was to evaluate effectiveness tacrolimus and clobetasol prevention rejection. Methods Seventy-six hemiface allotransplants, between ACI (RT1a) donors Lewis (RT1l) recipients, were performed 11 groups treated with or clobetasol, combination systemic cyclosporine A anti–αβ–T-cell receptor antibody 1 week. Topical increased...
Background: Insufficient soft-tissue coverage following total knee arthroplasty jeopardizes prosthesis retention and may lead to significant complications. The aim of this study was evaluate the natural history flap reconstruction defects. Methods: A retrospective review patients treated with flaps after failed between 1998 2013 conducted. Patients preexisting defects who required reactive were included in group 1. no defects, but extensive débridement during revision requiring immediate...
While prevalent in everyday life, smartphones are also finding increasing use as a medical care adjunct. The of smartphone technology postoperative cosmetic surgery adjunct for has received little attention the literature.The purpose this effort was to assess potential efficacy smartphone-based early follow-up program. Specifically, could photography provided by patient plastic surgeon first few days after allay patient's concerns, improve experience and, possibly, detect complications?From...