A5063959118- Enzyme Production and Characterization
- Biofuel production and bioconversion
- Salmonella and Campylobacter epidemiology
- Microbial Metabolites in Food Biotechnology
- Escherichia coli research studies
- Animal Nutrition and Physiology
- Tuberculosis Research and Epidemiology
- Viral gastroenteritis research and epidemiology
- Genomics and Phylogenetic Studies
- Enterobacteriaceae and Cronobacter Research
- SARS-CoV-2 and COVID-19 Research
- Virus-based gene therapy research
- Enzyme Catalysis and Immobilization
- Animal Virus Infections Studies
- Studies on Chitinases and Chitosanases
- Plant-Microbe Interactions and Immunity
- Microplastics and Plastic Pollution
- Biochemical and Molecular Research
- Antibiotic Resistance in Bacteria
- Microbial Natural Products and Biosynthesis
- Plant Pathogens and Fungal Diseases
- Microbial Metabolism and Applications
- Advanced Nanomaterials in Catalysis
- Food composition and properties
- Cancer therapeutics and mechanisms
University of Florida
2022-2025
Rajiv Gandhi Centre for Biotechnology
2021-2022
Kerala State Council for Science, Technology and Environment
2019-2020
Jawaharlal Nehru Tropical Botanic Garden and Research Institute
2017-2020
The human microbiome, a complex ecosystem of microorganisms residing in and on the body, plays pivotal role regulation wide range physiological processes, including digestion, immune responses, metabolic functions. In recent years, rapidly growing field microbiome-driven therapeutics has garnered significant attention owing to its potential revolutionize healthcare. This review explores evolving landscape microbiome-based therapies, with particular focus gut microbiome implications for both...
The current study was initiated when our specific-pathogen-free laboratory toms developed unexpectedly high levels of cross-reactive antibodies to human SARS-CoV-2 (SCoV2) receptor binding domain (RBD) upon mating with feline coronavirus (FCoV)-positive queens. Multi-sequence alignment analyses SCoV2 Wuhan RBD and four strains each from FCoV serotypes 1 2 (FCoV1 FCoV2) demonstrated an amino acid sequence identity 11.5% a similarity 31.8% FCoV1 (12.2% 36.5% for FCoV2 RBD). sera queens...
Plectranthus vettiveroides is a valuable medicinal and aromatic plant native to the Western Ghats, known for its essential oil extracted from roots. Its natural populations are vanishing due habitat distraction. The present study explores hydroponic cultivation as sustainable alternative it was conducted at Saraswathy Thangavelu Extension Centre, Jawaharlal Nehru Tropical Botanic Garden Research Institute, Puthenthope, Thiruvananthapuram, Kerala, India, between January 2023 May 2023. Apical...
Salmonella enterica serovar Enteritidis (S. Enteritidis) is one of the most common causes bacterial foodborne infections worldwide. It has an extensive host range, including birds and humans, making it adaptable serovars. This study aims to define virulence gene profile S. identify genes critical its specificity. Currently, there limited understanding molecular mechanisms that allow continue as important pathogen. To better understand may play a role in host-specific and/or fitness...
ABSTRACT Campylobacter hepaticus is known to cause spotty liver disease (SLD) in layer chickens around peak production. Here, we report the complete genome sequences of two C. strains, USA1 and USA5, from United States. The genomes comprise chromosomes 1,508,744 1,531,174 bp, respectively, with a G + C content 28%.
Neonatal Meningitis-causing Escherichia coli (NMEC) is the leading cause of neonatal meningitis and exhibits remarkable adaptability to diverse host environments. Understanding its transcriptional responses across different niches crucial for deciphering pathogenesis identifying potential therapeutic targets. We performed a comparative transcriptomic analysis NMEC RS218, prototype strain NMEC, under four distinct host-mimicking conditions: colonic fluid (CF), serum (S), human brain...
Neonatal Meningitis-causing Escherichia coli (NMEC) is the leading cause of neonatal meningitis and exhibits remarkable adaptability to diverse host environments. Understanding its transcriptional responses across different niches crucial for deciphering pathogenesis identifying potential therapeutic targets. We performed a comparative transcriptomic analysis NMEC RS218, prototype strain NMEC, under four distinct host-mimicking conditions: colonic fluid (CF), serum (S), human brain...
Shiga toxin-producing Escherichia coli (STEC) are notorious foodborne pathogens, capable of causing severe diarrhea and life-threatening complications in humans. Cattle, acting as both primary reservoirs asymptomatic carriers STEC, predominantly harbor the pathogen their rectoanal junction (RAJ), facilitating its transmission to humans through contaminated food sources. Despite central role cattle STEC transmission, molecular mechanisms governing STEC’s adaptation RAJ reservoir host...
The emergence of antimicrobial resistance (AMR) in pathogens transmitted through food poses a significant threat to global public health, complicating infection treatment and increasing mortality rates. This review explores the role resistome mapping as crucial tool for understanding transmission dynamics genes (ARGs) foodborne pathogens, such Salmonella, Escherichia coli, Listeria monocytogenes, Campylobacter spp., well various techniques mapping, metagenomic sequencing, PCR-based methods,...
Non-typhoidal Salmonella (NTS) infections in poultry, particularly commercial layer chickens, pose a critical risk to food safety and public health worldwide. NTS bacteria can remain undetected poultry flocks, contaminating products, potentially leading gastroenteritis humans. This review examines pre-harvest control strategies for including biosecurity protocols, vaccinations, feed additives, genetic selection, environmental management. By evaluating these strategies, this highlights the...
β-glucan rich cereals such as barley and oats serve a raw material in breweries also used an animal feed. Digestion of is often major hurdle, thus providing exogenous enzyme β-glucanase serves option. The present study takes effort for the expression over production genes from Streptomyces sp E. coli. exo-β-1,4-glucanase endo-β-1,3-glucanase encoding were isolated codon optimized significant-high levels obtained coli strain. expressed enzymes showed broad pH stability, good thermostability,...
Shiga toxin-producing Escherichia coli (STEC) are notorious foodborne pathogens capable of causing severe diarrhea and other life-threatening complications in humans. Cattle remain a major reservoir asymptomatic carriers STEC. In animals, the rectoanal junction (RAJ) serves as primary colonization site STEC playing critical role its transmission to humans through contaminated food sources. However, molecular mechanisms behind adaptation RAJ host subsequent infection human colonic epithelial...
The concern about the limited availability of petroleum-based fuels and their role in increasing CO2 levels atmosphere has sparked significant attention toward biofuel bioenergy production. global pursuit sustainable energy sources catalyzed innovative research into alternative production strategies. Transforming usable chemicals is gaining even more prominence. Cyanobacteria, renowned for photosynthetic ability, have emerged as promising candidates synthesis. Their ability to convert solar...
Abstract Screening of potential soil actinomycetes is static at infant phase because less than one part biodiversity has been explored. An important factor considered before isolating microorganisms with application understanding the and environmental features associated growth. Search distinctive enzymes from unusual ecological habitats are highly fascinating have great opportunities that may also pointed developments in high throughput screening programs. In present study Western Ghats hot...
Abstract The current study was initiated when our specific pathogen-free laboratory toms developed unexpectedly high levels of cross-reactive antibodies to human SARS-CoV-2 (SCoV2) receptor binding domain (RBD) upon mating with feline coronavirus (FCoV)-positive queens. Multi-sequence alignment analyses SCoV2 Wuhan RBD and four strains each from FCoV serotypes 1 2 (FCoV1, FCoV2) demonstrated amino acid sequence identity 11.5% similarity 31.8% FCoV1 RBD, as well 12.2% 36.5% for FCoV2 RBD....