- Celiac Disease Research and Management
- CAR-T cell therapy research
- Microscopic Colitis
- Hip and Femur Fractures
- Cardiac, Anesthesia and Surgical Outcomes
- Pancreatic and Hepatic Oncology Research
- Autoimmune and Inflammatory Disorders Research
- Biomedical Ethics and Regulation
- Clostridium difficile and Clostridium perfringens research
- Inflammatory Bowel Disease
- Gastrointestinal motility and disorders
- Pelvic and Acetabular Injuries
- Garlic and Onion Studies
- Gastrointestinal disorders and treatments
- Cancer Genomics and Diagnostics
- Hip disorders and treatments
- Bariatric Surgery and Outcomes
- Nutrition, Genetics, and Disease
- Biliary and Gastrointestinal Fistulas
- Palliative Care and End-of-Life Issues
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV/AIDS drug development and treatment
- Pediatric health and respiratory diseases
- Virus-based gene therapy research
- Eosinophilic Esophagitis
Beth Israel Deaconess Medical Center
2023-2025
Harvard University
2023-2025
Boston Children's Hospital
2021-2025
Johns Hopkins University
2023-2024
Deaconess Hospital
2021
Boston Children's Museum
2021
Hospital Vega Baja
2019
Clostridioides difficile infection (CDI) immune response is influenced by the innate and adaptive (humoral) systems. Our prior research found attenuated humoral responses to C in immunocompromised hosts (ICHs) with CDI. We sought evaluate whether CDI was ICH status. conducted a prospective study of hospitalized adults (acute diarrhea, positive stool nucleic acid amplification testing [NAAT], decision treat), without immunosuppression measured panel cytokines (granulocyte colony-stimulating...
Introduction We investigated the frequency of personal involvement with celiac disease (CeD) among CeD researchers and their motive to pursue research, compared in inflammatory bowel (IBD) or type 1 diabetes (T1D) research. Methods An online survey was sent CeD, IBD T1D researchers. Results 42% had an research interest, which similar (51%) significantly higher than respondents (27%, p<0.02). Discussion Personal is common may be beneficial when conducting patient-oriented
Obese habitus can lead to adverse outcomes for colorectal surgeries due technical challenges and pro-inflammatory immune mediators associated with excess adipose tissue. Surgical planning, pre-operative risk stratification, patient counseling of pediatric Crohn disease (CD) patients are limited by the scarcity data on this topic. We sought determine association between obesity hospital readmission in children CD undergoing intestinal resection.We used National Quality Improvement...
e16279 Background: To date, few targetable mutations have been found to enhance PDAC treatment. Next-generation sequencing (NGS) of somatic mutation profiles may help tailor cytotoxic chemotherapy selection and guide translational research. Methods: We analyzed NGS data from a retrospective cohort 142 patients with unresectable biopsy-proven August 2009 December 2022. Individual were grouped into 14 distinct signaling pathways: cell cycle, DNA damage repair, KIT, ErbB2, TP53, MAPK-RAS, PIK3,...
243 Background: This study aimed to examine the effects of hospice enrollment timing on survival and end-of-life quality life indicators for pancreatic ductal adenocarcinoma (PDAC) patients. Methods: A retrospective chart review 152 patients with biopsy-proven PDAC from August 2009 December 2022 at a single center was conducted. Patients were categorized based timing: Early-Hospice (EH) (≥ 60 days before death), Late-hospice (LH) (< days), No Hospice (NH). Parameters assessed included...