A5077231606- Genetic Neurodegenerative Diseases
- MicroRNA in disease regulation
- Mitochondrial Function and Pathology
- Amyotrophic Lateral Sclerosis Research
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Genetics and Neurodevelopmental Disorders
- Genomics and Rare Diseases
- Neurological disorders and treatments
- Endoplasmic Reticulum Stress and Disease
- Neurogenetic and Muscular Disorders Research
- Neurological diseases and metabolism
- DNA Repair Mechanisms
- RNA regulation and disease
Universidade Estadual de Campinas (UNICAMP)
2013-2024
Hospital de Clínicas da Unicamp
2013
Introduction: ALS is a rapidly progressive neurodegenerative disease. Diagnosis and prognosis estimation are often delayed because there no reliable biomarkers. In this scenario, microRNAs may be good candidates they released into the circulation by pathologically affected tissues display remarkable stability in body fluids. Objectives: to identify differentially expressed skeletal muscle plasma of patients when compared healthy controls. Method: We perfomed biopsies Biceps brachii muscles...
OBJECTIVE: The aim of the present study was to analyze expression miR-124 in acute phase pilocarpine epilepsy model. Thus, investigating whether abnormalities microglial activation, usually observed this model, could be mediated by microRNA deregulation.