A5006334709- Organometallic Compounds Synthesis and Characterization
- Mesoporous Materials and Catalysis
- Metal-Organic Frameworks: Synthesis and Applications
- Metal complexes synthesis and properties
- Dendrimers and Hyperbranched Polymers
- Ferrocene Chemistry and Applications
- Marine Biology and Environmental Chemistry
- Synthesis and biological activity
- Corrosion Behavior and Inhibition
- Synthesis and Characterization of Heterocyclic Compounds
- Nanoparticle-Based Drug Delivery
- Nanocluster Synthesis and Applications
- Advanced Drug Delivery Systems
- Advanced Nanomaterials in Catalysis
- Mobile Learning in Education
- Lanthanide and Transition Metal Complexes
- Advanced Photocatalysis Techniques
- Supramolecular Chemistry and Complexes
- Antimicrobial agents and applications
- Innovative Teaching Methods
- Polyoxometalates: Synthesis and Applications
- Science Education and Pedagogy
- Nanoparticles: synthesis and applications
- Bone health and treatments
Universidad Rey Juan Carlos
2020-2025
Universidad Nacional de Córdoba
2024
Universidad Complutense de Madrid
2020
Three different multifunctional nanosystems based on the tethering onto mesoporous silica nanoparticles (MSN) of fragments such as an organotin-based cytotoxic compound Ph3Sn{SCH2CH2CH2Si(OMe)3} (MSN-AP-Sn), a folate fragment (MSN-AP-FA-Sn), and enzyme-responsive peptide able to release metallodrug only inside cancer cells (MSN-AP-FA-PEP-S-Sn), have been synthesized fully characterized by applying physico-chemical techniques. After that, in vitro deep determination therapeutic potential...
Five different silica nanoparticles functionalized with vitamin B12, a derivative of coumarin found in green plants and minimum content an organotin(IV) fragment (1-MSN-Sn, 2-MSN-Sn, 2-SBA-Sn, 2-FSPm-Sn 2-FSPs-Sn), were identified as excellent anticancer agents against triple negative breast cancer, one the most diagnosed aggressive cancerous tumors, very poor prognosis. Notably, compound 2-MSN-Sn shows selectivity for cancer cells luminescent properties detectable by imaging techniques once...
Nanozymes are nanostructured artificial enzymes that have attracted great attention among researchers because of their ability to mimic relevant biological reactions carried out by natural counterparts, but with the capability overcome enzymes’ drawbacks such as low thermostability or narrow substrate scope. The promising enzyme-like properties these systems make nanozymes excellent candidates for innovative solutions in different scientific fields analytical chemistry, catalysis medicine....
Nanoscale materials have demonstrated a very high potential in anticancer therapy by properly adjusting their functionalization and physicochemical properties. Herein, we report the synthesis of some novel vanadocene-loaded silica-based nanomaterials incorporating four different S-containing amino acids (penicillamine, methionine, captopril, cysteine) fluorophores (rhodamine B, coumarin 343 or Alexa Fluor™ 647), which been characterized diverse solid-state spectroscopic techniques viz; FTIR,...
Silica-based nanomaterials functionalized with an organotin( iv ) compound showed outstanding eradication of both E.coli and S. aureus biofilms good antibacterial properties through ROS RNI formation.
Nanostructured materials possess promising potential for cancer therapy through precise adjustment of their functionalization and physicochemical attributes. This study primarily focuses on the synthesis characterization mesoporous silica nanoparticles (MSN) that are functionalized with titanocene dichloride (a therapeutic agent) one several amino acids—cysteine, captopril, penicillamine, or methionine—utilizing 3‐aminopropyltriethoxysilane (AP) as a linker. yielded four innovative...
Abstract The current search for more effective and milder cancer treatments has led to the development of a wide variety multifunctional nanoplatforms that are designed both diagnose treat cancer. In this study, optimization synthesis theranostic materials based on mesoporous silica nanoparticles (MSNs) functionalized with different cytotoxic (organotin(IV) compounds), imaging (fluorescein and/or indocyanine green), targeting agents interest, such as albumin (HA), is achieved by using...