A5008486333- Syphilis Diagnosis and Treatment
- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Reproductive tract infections research
- Cervical Cancer and HPV Research
- Reproductive System and Pregnancy
- Plant Pathogens and Fungal Diseases
- Neonatal skin health care
National Health Laboratory Service
2023
University of KwaZulu-Natal
2020
Background . Gardnerella vaginalis , a microorganism highly linked to bacterial vaginosis (BV), is understudied in terms of genotypic heterogeneity South African populations. This study investigated the prevalence G. genotypes BV-positive, BV-intermediate, and BV-negative pregnant women. Methods The population included <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>354</mml:mn></mml:math> women recruited from public hospital...
We performed in vitro antifungal susceptibility testing of manogepix against the yeast phase 78 Emergomyces africanus, 2 pasteurianus, and 5 Blastomyces emzantsi isolates using a reference broth microdilution method following Clinical Laboratory Standards Institute recommendations. All three pathogens had low minimum inhibitory concentrations ranging from <0.0005 to 0.008 mg/L. Manogepix should be investigated animal models potentially future human clinical trials for endemic mycoses.