A5012266366- Capital Investment and Risk Analysis
- Advanced Optical Imaging Technologies
- Visual perception and processing mechanisms
- Stochastic processes and financial applications
- Economic theories and models
- Virtual Reality Applications and Impacts
- Climate Change Policy and Economics
- Reservoir Engineering and Simulation Methods
- Mining Techniques and Economics
- Electric Power System Optimization
- Financial Reporting and Valuation Research
- Transportation Planning and Optimization
- Supply Chain and Inventory Management
- Banking stability, regulation, efficiency
- Energy Load and Power Forecasting
- Financial Markets and Investment Strategies
- Image and Video Quality Assessment
- Smart Grid Energy Management
- Nuclear and radioactivity studies
- Wind Energy Research and Development
- Tactile and Sensory Interactions
- Credit Risk and Financial Regulations
- Risk Perception and Management
- Color Science and Applications
- Advanced Numerical Methods in Computational Mathematics
University of Manchester
2013-2024
Apple (United States)
2017
University of California, Berkeley
2011-2016
Applied Mathematics (United States)
2010-2014
University of California, San Francisco
2014
Bioengineering Center
2014
Massachusetts General Hospital
2009-2013
Harvard University
2010-2011
Honolulu University
1992
The intestinal microbiota plays a critical role in maintaining human health; however, the mechanisms governing normal homeostatic number and composition of these microbes are largely unknown. Previously it was shown that alkaline phosphatase (IAP), small brush border enzyme, functions as gut mucosal defence factor limiting translocation bacteria to mesenteric lymph nodes. In this study IAP preservation homeostasis investigated.Bacterial culture performed aerobic anaerobic conditions quantify...
Intestinal alkaline phosphatase (IAP) is a small intestinal brush border enzyme that has been shown to function as gut mucosal defense factor, but its precise mechanism of action remains unclear. We investigated the effects IAP on specific bacteria and bacterial components determine molecular targets. Purulent fluid from cecal ligation puncture model, live heat-killed (Escherichia coli, Salmonella typhimurium, Listeria monocytogenes), variety proinflammatory ligands (LPS, CpG DNA, Pam-3-Cys,...
Stereoscopic 3D (S3D) displays provide an additional sense of depth compared to non-stereoscopic by sending slightly different images the two eyes. But conventional S3D do not reproduce all natural cues. In particular, focus cues are incorrect causing mismatches between accommodation and vergence: The eyes must accommodate display screen create sharp retinal even when binocular disparity drives converge other distances. This mismatch causes visual discomfort reduces performance. We propose...
Listeria monocytogenes vectors have shown promise for delivery of viral and tumor antigens in animals. We used two mutant vector strains deleted actA/plcB (BMB72) actA/inlB (BMB54), engineered both to secrete a heterologous nucleoprotein antigen from the Influenza A virus. Strains were evaluated vitro mice. Twenty-two healthy volunteers received single oral doses either strain physiological study safety, shedding, immunogenicity. Volunteers observed hospital seven days had daily blood...
The phenomenon of Unaccounted-for-Gas (UAG) in natural gas transmission networks can be summarised as the failure to account for a percentage network throughput on either side balancing equation - typically around 0.3% per annum, cost directly absorbed by transporter. This article presents case study historical UAG data from UK's National Gas Transmission System, compromising two instances significant under-reads amounting 1617 GWh and 1141 respectively. Statistical process control...
The electricity market in the UK has been reformed over recent years resulting introduction of 'Contracts for Difference' as an option wind producers. They can use these contracts only if at same time they enter into other contracts, i.e., Power Purchase Agreements or participation wholesale market. Most producers prefer holding a long-term Agreement with another party. However, agreements do not always offer best terms producer due to them selling energy lower prices than those spot prices....
Corporation and is an Adjunct Professor at Columbia Business School. Paul Johnson a Managing Director Technology Industry Analyst Robertson Stephens & Company Although the notion of competitive advantage has been unassailable importance in valuation, it subject that not explicitly addressed finance textbooks way commensurate with its importance. Further, many analysts strategic planners adhere to discounted-cash-flow framework reduce model's validity by using explicit forecast periods do...
When a mining company begins extraction from finite resource, it does so in the presence of numerous uncertainties. One key uncertainty is future price commodity being extracted, since large enough drop can make resource no longer cost-effective to extract, resulting mine closed down. By specifying stochastic process, and implementing financial-type model which leads use partial differential equations, this paper creates framework for efficiently capturing probability remaining open...
Abstract Large screen Organic Light Emitting Diode (OLED) technology is finally emerging as a ready for consumer use. OLED has number of areas in which it can principle be better than Liquid Crystal Displays (LCDs); two ways particular are that achieve black levels much darker LCDs, and the pixels switch extremely rapidly. These differences permit displays to outperform LCD under conventional scenarios, but also enable some dramatically improved stereoscopic 3D (s3D) displays, including...
Color breakup is an artifact seen on displays that present colors sequentially. When the eye tracks a moving object such display, different land places retina, and this gives rise to visible color fringes at object's leading trailing edges. Interestingly, also observed when stationary moves by. Using novel psychophysical procedure, we measured both viewers tracked did not track object. Breakup was somewhat more in tracking than non-tracking condition. The video frames contained three...
Attenuated Listeria monocytogenes vaccine strains have been administered intravenously (Le et al. [1], Maciag [2]) and orally (Angelakopoulos [3], Johnson [4]) to humans. Here, one was given transcutaneously with cholera toxin adjuvant. Eight healthy volunteers were studied (5 active, 3 placebo). Safety assessed by physical exam labs. Systemic immunological responses measured ELISA IFN-gamma ELISpot. 4/5 active had cellular listerial antigens. 5/5 showed humoral toxin. An attenuated L....
A mixed financial/physical partial differential equation (PDE) can optimize the joint earnings of a single wind power generator (WPG) and generic energy storage device (ESD). Physically, PDE includes constraints on ESD's capacity, efficiency maximum speeds charge discharge. There is mean-reverting daily stochastic cycle for WPG output. only be produced or delivered at finite rates. All suppliers must commit hourly to rate delivery C, which continuous control variable that changed hourly....
Analytic solutions exist only for highly idealized simple problems in stochastic storage; while simulation is available complex problems, it generally impractically slow. In this paper, a system of partial differential equations (PDEs), based on novel combination the techniques used to value options finance, developed and shown efficiently storage. The PDE requires somewhat non-standard (but well-defined) numerical solution methods, which are up nine orders magnitude faster than (and yet...
Temporal multiplexing is a popular approach for presenting different images to the two eyes in stereoscopic 3D (S3D) displays. We examined visibility of flicker and motion artifacts—judder, blur, edge banding—on 240-Hz temporally multiplexed S3D OLED display. Traditionally, frame rate 120 Hz (60 per eye) used avoid visible flicker, but there evidence that higher rates provide benefits. In series psychophysical experiments, we measured artifacts on display using temporal those 60-Hz LCD...
Stereoscopic 3D (S3D) displays use spatial or temporal interlacing to send different images the two eyes. Temporal delivers left and right eyes alternately in time; it has high effective resolution but is prone artifacts. Spatial even pixel rows one eye odd other simultaneously; subject limitations such as reduced resolution. We propose a spatiotemporal-interlacing protocol that interlaces left- right-eye views spatially, with being delivered each alternating frame. performed psychophysical...
The dynamic process of ground contamination after a major nuclear accident is modelled, and the system then extended to include transient equations describing three broad countermeasures: food bans, remediation population movement (relocation repopulation). Countermeasures are assumed be applicable once deposition period has ended surface measurements have stabilised. A value function constructed account for economic factors, including allowance detrimental effect on human health radiation...
We develop a decision-making model that describes optimal protection and recovery strategies for single economic location affected by radioactive release from the nearby Nuclear Power Plant. The initial period of deposition is characterised high degrees uncertainty, which likely to lead precautionary emergency measures being carried out regardless actual dangers public, therefore it excluded optimisation problem. Instead, analysis performed on timescale weeks, months, years decades after...
Wind power is intermittent and causes problems to the operation of electric systems. This leads need for flexible battery storage units smooth wind output. However, volatile profile output affects operational performance units. We propose here an optimisation model define optimal hourly commitment a unit while also including relevant constraints modelling its degradation. Results show that although farm can have reduced revenue in shorter-term because these constraints, increases longer-term...
Temporal interlacing is a method for presenting stereoscopic 3D content whereby the two eyes' views are presented at different times and optical filtering selectively delivers appropriate view to each eye. This approach prone distortions in perceived depth because visual system can interpret temporal delay between binocular as spatial disparity. We propose novel color-interlacing display protocol that reverses order of presentation green primary but maintains red blue primaries: During first...