A5062255244- Catalytic C–H Functionalization Methods
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Catalytic Cross-Coupling Reactions
- Organoboron and organosilicon chemistry
- Metal-Organic Frameworks: Synthesis and Applications
- Advanced Photocatalysis Techniques
- Fluorine in Organic Chemistry
- Quantum Dots Synthesis And Properties
- Synthesis and biological activity
- Asymmetric Hydrogenation and Catalysis
- TiO2 Photocatalysis and Solar Cells
- Carbon and Quantum Dots Applications
- Adsorption and biosorption for pollutant removal
- Covalent Organic Framework Applications
- Electrocatalysts for Energy Conversion
- Synthesis and Characterization of Heterocyclic Compounds
- Chromium effects and bioremediation
- Nanoparticles: synthesis and applications
- Chemical Reactions and Isotopes
- Plant-derived Lignans Synthesis and Bioactivity
- Membrane Separation and Gas Transport
- Copper-based nanomaterials and applications
- Advanced Nanomaterials in Catalysis
- Fuel Cells and Related Materials
Lahore University of Management Sciences
2016-2025
Michigan State University
2005-2020
Michigan United
2019
Ir-catalyzed borylation of 2-substituted indoles selectively yields 7-borylated products in good yields. N-Protection, required for previous functionalizations indoles, is unnecessary.
Ir-catalyzed borylations of 4-substituted benzonitriles are described. In contrast to electrophilic aromatic substitutions and directed ortho metalations, C−H activation/borylation enables functionalization at the 2-position, adjacent cyano group, when 4-subsitutent is larger than cyano. When an excess borane reagent used, diborylation can be achieved with a single regioisomer being formed in certain cases. Extension sterically borylation cyano-substituted, five- six-membered ring...
Ir-catalyzed deborylation can be used to selectively deuterate aromatic and heteroaromatic substrates. Combined with the selectivities of C-H borylations, uniquely labeled compounds prepared. In addition, diborylation/deborylation reactions provide monoborylated regioisomers that complement those prepared by borylation. Comparisons between deborylations Pd-catalyzed diborylated indoles described Movassaghi are made. The process is more effective for deborylating aromatics generally in...
The growing concerns about environmental pollution, particularly water are causing an increasing alarm in modern society. One promising approach to address this issue involves engineering existing materials enhance their effectiveness. A one-step solvothermal reconstruction was used build eco-friendly two-dimensional (2D) AlNiZn-LDH/BDC MOF composite. characterizations confirm the formation of a metal–organic framework (MOF) at layered double hydroxide (LDH) surface. resulting synthesized...
Agricultural soils contain both heavy metals and pesticides originating from various agricultural practices. It is quite important to study the relationships between these two classes of compounds. To accomplish this, 52 soil samples were collected cotton fields analyzed for their metal contents (Ni, Cu, Co, Pb, Cr, Cd) levels most commonly used (imidacloprid, acetamiprid, emamectin). FAAS was estimation determined by HPLC equipped with UV detector. The results revealed slightly enhanced Ni...
Amide directed C-H borylation using ≥two equiv. of BBr3 forms borenium cations containing a R2N(R')C[double bond, length as m-dash]O→B(Ar)Br unit which has significant Lewis acidity at the carbonyl carbon. This enables reduction amide to an amine hydrosilanes. approach can be applied sequentially in one-pot electrophilic borylation-reduction process, for phenyl-acetylamides generates ortho borylated compounds that directly oxidised 2-(2-aminoethyl)-phenol. Other substrates amenable sequence...
Ag 2 O/CuO composite ensures complete mineralization of imidacloprid so helps ensure a greener environment.
Five-coordinate boryl complexes relevant to Ir mediated C–H borylations have been synthesized, providing a glimpse of the most fundamental step in catalytic cycle for first time.
By modifying ligand steric and electronic profiles it is possible to C-H borylate ortho or meta substituents in aromatic heteroaromatic compounds, where differences between accessible sites are small. Dramatic effects on selectivities reactions using B2pin2 4,4,5,5-tetramethyl-1,3,2-dioxaborolane (HBpin) described for the first time. Judicious borane combinations give highly regioselective borylations substrates typical borylation protocols afford poor selectivities.
MOFs are emerging photocatalysts designed by tuning organic ligands and metal centers for optimal efficiency.
The NHC-Se scaffold has emerged as an intriguing target, opening new avenues for discovering compounds that could significantly improve public health. Recently, extensive efforts have been made to synthesize NHC-Se-based organic various biomedical applications. Herein, we disclose a straightforward method access series of N-heterocyclic carbene (NHC)-derived organoselenium molecules functionalized with amide moiety. parent adduct pendent ester moiety is sufficiently activated facilitate...
A one-pot protocol for converting 1,3- and 1,4-substituted aryl halides to arylamine boronate esters is described. This achieved by sequential Ir-catalyzed aromatic borylation at the least hindered C−H bond of halide subsequent Pd-catalyzed C−N coupling position crude arylboronic ester.
Anthropogenic processes are one of the main contributors for presence heavy metals in air, land and water sources, leading to environmental pollution. In present study, Bacillus altitudinis MT422188 was used determining its potential role zinc bioremediation. After bacterium isolated characterized, optimum growth conditions were determined. The parameters, antioxidative biosorption potential, motility chemotactic behavior, as well physicochemical nature isolate determined absence zinc....
The incessant pervasiveness of heavy metals in the environment is one precursory factors pollution. This research study was endeavored upon to investigate bioremediation potential a nickel (Ni)-resistant bacterial isolate, identified as Bacillus altitudinis MT422188, whose optimum growth parameters were demonstrated at pH 7, temperature 32 °C, and 1 mM phosphate. Minimal Inhibitory Concentration (MIC) EC50 for Ni observed be 20 11.5 mM, respectively, whereas cross heavy-metal resistance...
The low toxicity of Se nanoparticles (NPs) makes it a suitable candidate for biomedical and sensing applications. Herein, we, the first time, report modification pencil graphite electrode with nanostructures (Se/PGE) by facile chemical bath deposition (CBD) method. Hydrazine, routine in various industries, is toxic even trace amounts poses serious threat due to its carcinogenic mutagenic nature. Therefore, crucial detect presence aqueous media. Se/PGE exhibited outstanding, reproducible,...