A5032203638- Neurological disorders and treatments
- Genetic Neurodegenerative Diseases
- Parkinson's Disease Mechanisms and Treatments
- Genetics and Neurodevelopmental Disorders
- COVID-19 and Mental Health
- Neuroscience and Neural Engineering
- COVID-19 Clinical Research Studies
- Mitochondrial Function and Pathology
- Long-Term Effects of COVID-19
- Autism Spectrum Disorder Research
- Autoimmune Neurological Disorders and Treatments
- Ion channel regulation and function
- Parkinson's Disease and Spinal Disorders
- Molecular Communication and Nanonetworks
- Glycogen Storage Diseases and Myoclonus
- Neurological and metabolic disorders
- RNA regulation and disease
- Nerve Injury and Rehabilitation
- Ophthalmology and Eye Disorders
- Lysosomal Storage Disorders Research
- CNS Lymphoma Diagnosis and Treatment
- Wireless Body Area Networks
- Neurosurgical Procedures and Complications
- Tracheal and airway disorders
- Child Development and Digital Technology
Hospital Universitario Rey Juan Carlos
2019-2022
Hospital Universitario Infanta Leonor
2022
Hospital Universitario 12 De Octubre
2015-2021
Universidad Complutense de Madrid
2019-2020
Biomedical Research Networking Center on Neurodegenerative Diseases
2020
Hospital Universitario Príncipe de Asturias
2018
Research Institute Hospital 12 de Octubre
2017
Mobile technology is opening a wide range of opportunities for transforming the standard care chronic disorders. Using smartphones as tools longitudinally tracking symptoms could enable personalization drug regimens and improve patient monitoring. Parkinson's disease (PD) an ideal candidate these tools. At present, evaluation PD signs requires trained experts to quantify motor impairment in clinic, limiting frequency quality information available understanding status progression disease. can...
Abstract Essential tremor (ET) is a major cause of disability and not effectively managed in half the patients. We investigated whether mechanical vibration could reduce ET by selectively recruiting afferent pathways. used piezoelectric actuators to deliver vibratory stimuli hand forearm during long trials (4 min), while we monitored using inertial sensors. analyzed effect four stimulation strategies, including different constant variable frequencies, 18 Although there was clear homogeneous...
A 40-year-old woman with well-controlled HIV infection had a vertebrobasilar stroke secondary to endocarditis by Coxiella burnetii (figure 1), left hemiparesis remaining.
Madelung’s disease (benign symmetric lipomatosis) is a rare syndrome in which there are multiple lipomas around the neck, upper limbs and trunk context of chronic alcoholism. We report on female patient with slightly progressive myoclonus, neuropathy, myopathy, ataxia respiratory systemic involvement (labelled past as disease). Multisystem family history led to development mitochondrial genetic tests, can assess two concurrent mutations: m.8344A>G mutation MT-TK gene, related MERRF...
Smartphone use in biomedical research is becoming more prevalent different clinical settings. We performed a pilot study to obtain information on smartphone by patients with essential tremor (ET) and healthy controls, view determining whether performance of touchscreen tasks between these groups describing interaction factors.A total 31 ET 40 sex- age-matched controls completed descriptive questionnaire about the smartphones. Participants subsequently interacted an under-development Android...
This paper presents a classification model for the automatic quantification of tremor severity in patients with essential (ET). The system is based on signals measured by two commercial smartwatches that wear their wrist and ankle. register acceleration angular velocity these body segments. A set nine features were used to train algorithm. proposed algorithm C4.5 decision tree classifier. It able assess rest kinetic (postural or action) tremor.The method was evaluated using data collected...
We read with interest the article by De Vleeschhauwer et al1 about touchscreen skills in patients Parkinson's disease (PD). acknowledge that this pioneer and exhaustive effort highlights precisely some of main difficulties these encounter while interacting devices. One examples is prolonged duration sliding tasks performed patients. The reveals patients' accuracy their intertap interval similar to those shown participants without PD. achieved comparable results previous research. In...
A 56-year-old woman presented to the emergency department with sudden onset of left-sided ptosis, perioral paraesthesias and dizziness, without imbalance or vertigo, after getting up from bed. She had hyperlipidaemia was a smoker. General examination normal. On neurological there asymmetric bilateral more on left, pupillary eye movement abnormalities (figure 1). Other cranial nerves, motor sensory examination, coordination, posture gait were unremarkable. The Cogan lid-twitch test eyelid...
Bilateral obturator nerve injury during pelvic surgery is an infrequent cause of lower limb paraparesis. We report the case a 45-year-old woman with large uterine leiomyoma who underwent simple total hysterectomy and bilateral salpingectomy. At 24 h after surgery, patient noticed loss muscle strength when adducting both legs. She had no problem other movements sensory or sphincter abnormalities. Neurological examination confirmed that there was only in adductor muscles, preserved function...
Smartphones use in biomedical research is becoming more prevalent different clinical settings. We performed a pilot study to obtain information on smartphone by patients with essential tremor (ET) and healthy controls, view determining whether performance of touchscreen tasks between these groups describing interaction factors.
Superficial siderosis of central nervous system is a rare disease that consists in the continuous subarachnoid leakage red blood cells into space, leading to progressive neurological deficits. We present first clinical description patient with superficial and hemophilia as trigger bleedings. Brain MRI was crucial for diagnosis.