A5005778457- Knowledge Management and Sharing
- Open Source Software Innovations
- Private Equity and Venture Capital
- CAR-T cell therapy research
- Wikis in Education and Collaboration
- Research Data Management Practices
- Software Engineering Research
- scientometrics and bibliometrics research
- Sperm and Testicular Function
- Reproductive Biology and Fertility
- RNA Interference and Gene Delivery
- CRISPR and Genetic Engineering
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Nationwide Children's Hospital
2018
Max Planck Institute of Immunobiology and Epigenetics
1999
CRISPR/Cas9 technology is accelerating genome engineering in many cell types, but so far, gene delivery and stable modification have been challenging primary NK cells. For example, transgene using lentiviral or retroviral transduction resulted a limited yield of genetically-engineered cells due to substantial procedure-associated apoptosis. We describe here DNA-free method for editing human expanded Cas9 ribonucleoprotein complexes (Cas9/RNPs). This allowed efficient knockout the TGFBR2...
Open source software projects usually acknowledge contributions with text files, websites, and other idiosyncratic methods. These data sources are hard to mine, which is why contributorship most frequently measured through changes repositories, such as commits, pushes, or patches. Recently, some open have taken recording contributor actions standardized systems; this opens up a unique opportunity understand how community-generated notions of map onto codebases the measure contribution. Here,...
Invisible labor is work that not fully visible, appropriately compensated, or both. In open source software (OSS) ecosystems, essential tasks do involve code (like content moderation) often become invisible to the detriment of individuals and organizations. However, so difficult measure we know how much OSS activities are invisible. Our study addresses this challenge, demonstrating roughly half We by developing a survey technique with cognitive anchoring measures developer self-assessments...