Jack A. Doolan

ORCID: 0000-0003-2693-7515
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About
Contact & Profiles
Research Areas
  • Spaceflight effects on biology
  • Sports Dynamics and Biomechanics
  • Bacterial biofilms and quorum sensing
  • Dendrimers and Hyperbranched Polymers
  • Supramolecular Self-Assembly in Materials
  • Graphene and Nanomaterials Applications
  • Polydiacetylene-based materials and applications
  • Nanoplatforms for cancer theranostics

University of Kent
2021-2023

Abstract Extreme energy-dissipating materials are essential for a range of applications. The military and police force require ballistic armour to ensure the safety their personnel, while aerospace industry requires that enable capture, preservation study hypervelocity projectiles. However, current standards display at least one inherent limitation, such as weight, breathability, stiffness, durability failure preserve captured To resolve these limitations, we have turned nature, using...

10.1038/s41565-023-01431-1 article EN cc-by Nature Nanotechnology 2023-07-03

Many chemotherapeutic drugs have a narrow therapeutic window due to inefficient tumour cell permeation. Supramolecular self-associating amphiphilic salts (SSAs) are unique class of small molecules that offer potential as next generation cancer and/or enhancement agents. Herein, we demonstrate the cytotoxicity seven SSAs towards both ovarian and glioblastoma cells. We also utilize intrinsic fluorescent properties one these lead provide evidence for this compound bind exterior surface permeate...

10.1039/d1ra02281d article EN cc-by RSC Advances 2021-01-01

Abstract Extreme energy dissipating materials are essential for a range of applications. The military and police force require ballistic armour to ensure the safety their personnel, while aerospace industry requires that enable capture, preservation study hypervelocity projectiles. However, current standards display at least one inherent limitation. To resolve these limitations we have turned nature, utilising proteins evolved over millennia effective dissipation. Specifically, recombinant...

10.1101/2022.11.29.518433 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-11-29
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