A5008672754- Health Systems, Economic Evaluations, Quality of Life
- Hormonal Regulation and Hypertension
- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Genetic Syndromes and Imprinting
- Primary Care and Health Outcomes
- Bone health and treatments
- Antibiotics Pharmacokinetics and Efficacy
- Parathyroid Disorders and Treatments
- Trauma and Emergency Care Studies
- Drug Transport and Resistance Mechanisms
- Antibiotic Resistance in Bacteria
- Frailty in Older Adults
- Healthcare cost, quality, practices
- Antimicrobial Resistance in Staphylococcus
- Maternal and fetal healthcare
- Sepsis Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
- Liver Diseases and Immunity
- Veterinary medicine and infectious diseases
- Pediatric Hepatobiliary Diseases and Treatments
- Conferences and Exhibitions Management
- Pharmaceutical Practices and Patient Outcomes
- Gastric Cancer Management and Outcomes
Flinders Medical Centre
2018-2024
Women's and Children's Health Network
2021
Flinders University
2020
Royal Adelaide Hospital
2019
Intrahepatic cholestasis of pregnancy (ICP) is a liver disease, characterised by pruritus and increased total serum bile acids (TSBA), Australian incidence 0.6-0.7%. ICP diagnosed non-fasting TSBA ≥19 μmol/L in pregnant woman with without rash known pre-existing disorder. Peak ≥40 ≥100 identify severe very disease respectively, associated spontaneous preterm birth when severe, stillbirth, severe. Benefit-vs-risk for iatrogenic remains uncertain. Ursodeoxycholic acid the best pharmacotherapy...
Background The Society of Australia and New Zealand (SOMANZ) published its first sepsis in pregnancy the postpartum period guideline 2017 ( Aust N Z J Obstet Gynaecol , 57, 2017, 540). In intervening 6 years, maternal mortality from has remained static. Aims To update clinical practice with a review subsequent literature. particular, to definition screening tools for diagnosis sepsis. Materials Methods A multi‐disciplinary group clinicians experience all aspects care pregnant women analysed...
Asymptomatic mild primary hyperparathyroidism is increasingly being identified during pregnancy. Recent studies have demonstrated inconsistent findings with regard to pregnancy complications and the need for surgical intervention pregnancy.A retrospective audit of outcomes pregnancies complicated by hypercalcaemia over a 15-year period was performed.Twenty-nine 26 women were identified, corresponding 37 cases per 100,000 deliveries. Hypercalcaemia due in 90% cases, mean serum calcium 2.89...
Background: Older patients from nursing homes are commonly exposed to polypharmacy before a hospital admission. Deprescribing has been promoted as solution this problem, though systematic reviews have not found benefit. The aim of study was understand if in-hospital deprescribing certain classes medications is associated with benefits or risks. Methods: We conducted prospective, multicentre, cohort in 239 medical inpatients ⩾75 years (mean age 87.4 years) who were (⩾5 medications) prior...
Abstract Objectives Published evidence on health service interventions should inform decision-making in local services, but primary effectiveness studies and cost-effectiveness analyses are unlikely to reflect contexts other than those which the evaluations were undertaken. A ten-step framework was developed applied use published as basis for local-level economic that estimate expected costs effects of new intervention options specific contexts. Methods Working with a multidisciplinary group...
Mineralocorticoid receptor antagonists are highly effective in the management of resistant hypertension and primary hyperaldosteronism. Recent studies demonstrate that mineralocorticoid significantly reduce blood pressure, severity obstructive sleep apnoea arterial stiffness patients with moderate-severe apnoea. Eplerenone is a selective antagonist does not act as an androgen blocker, thus reducing risk fetal anti-androgenic effects. Rat rabbit demonstrated when exposed to 30 times...