A5084065328- Potassium and Related Disorders
- Membrane-based Ion Separation Techniques
- Heart Failure Treatment and Management
- Dermatology and Skin Diseases
- Magnesium in Health and Disease
- Bipolar Disorder and Treatment
- Urticaria and Related Conditions
- Renal and related cancers
- Electrolyte and hormonal disorders
- Psoriasis: Treatment and Pathogenesis
- Herpesvirus Infections and Treatments
- COVID-19 Impact on Reproduction
- Plant Pathogens and Fungal Diseases
- Polyomavirus and related diseases
- Cardiovascular Function and Risk Factors
- Molten salt chemistry and electrochemical processes
- Food Allergy and Anaphylaxis Research
- Inhalation and Respiratory Drug Delivery
- Cardiac pacing and defibrillation studies
- Fungal Infections and Studies
- Cytomegalovirus and herpesvirus research
- SARS-CoV-2 and COVID-19 Research
- Organ Donation and Transplantation
- Neurological and metabolic disorders
- Antifungal resistance and susceptibility
Vifor Pharma (United States)
2020-2024
Vifor Pharma (Switzerland)
2023
Intermountain Medical Center
2020
Astellas Pharma (United States)
2017-2018
Rationale & Objective: The Selective Cytopheretic Device for Pediatrics (SCD-PED) is a cell-directed extracorporeal therapy approved by US FDA pediatric patients with acute kidney injury (AKI) due to sepsis or septic condition, requiring antibiotics and continuous renal replacement (CRRT). This study aimed estimate hospitalization costs outcomes of SCD-PED leveraging the Kids' Inpatient Database (KID) studies. Study Design: Publicly available cost data were combined clinical metrics from...
Background: Sodium zirconium cyclosilicate (SZC) and patiromer (PAT) are potassium binders that differ by exchange ion, sodium, calcium, respectively. There is limited data on whether using sodium could impact the risks of hospitalizations for heart failure (HHF) or severe edema in patients with hyperkalemia. Objectives: To assess occurrence rates pre-specified major encounters potentially related to electrolyte-/fluid-related imbalances (including HHF, edema) among new users PAT SZC...
Abstract Background CMV infection (CMV‐I) remains an important complication of hematopoietic stem cell transplantation (HSCT). Methods This was a retrospective, single‐center cohort study in HSCT recipients. Primary outcomes were adjusted cost and all‐cause mortality. Secondary analyses investigated risk factors the effect serostatus. Results Overall, 690 transplant episodes included (allogeneic [n = 310]; autologous 380]). All received preemptive antiviral therapy at first detectable...
Background Hyperkalemia is a frequent and serious complication in chronic kidney disease (CKD) that can impede continuation of beneficial evidence-based therapies. Recently, novel therapies such as patiromer have been developed to treat hyperkalemia, but their optimal utility hinges on adherence. Social determinants health (SDOH) are critically important impact both medical conditions treatment prescription This analysis examines SDOH influence adherence or abandonment prescriptions for...
Abstract Background Hyperkalaemia (HK) is a serious and potentially life-threatening condition. Both acute chronic conditions may alter potassium homeostasis. Our aim to describe HK incidence, clinical outcomes, associated resource use within large, integrated healthcare system. Methods Adult patients seen at Intermountain Healthcare facilities with serum (sK) result between January 1, 2003 December 31, 2018 were retrospectively studied. Descriptive assessment of population detected HK,...
Abstract Aims This analysis qualitatively describes the impact of hyperkalaemia (HK) and renin‐angiotensin‐aldosterone system inhibitor (RAASi) use on clinical outcomes in patients with heart failure (HF). Methods results Patients were included if they ≥18 years old; had a serum potassium result between 1 January 2003 3 December 2018; ≥2 separate, non‐urgent care or emergency department encounters; an HF diagnosis. Criteria met by 52 253 patients; 48 333 sufficient follow‐up for analysis....
Studies suggest that continuous long-term use of patiromer by patients with hyperkalemia is associated less health care resource utilization compared not using potassium binders.
Abstract Background A better understanding of the epidemiology and clinical features invasive fungal disease (IFD) is integral to improving outcomes. Here we aimed describe incidence, outcomes IFD in a large US healthcare network. Methods We developed novel method cohort discovery query all available records Intermountain Healthcare electronic data warehouse from 2006 2015 for associated with (Figure 1). Resulting were overlaid 124 different combinations identify high-probability cases. The...
Abstract Background: Hyperkalaemia (HK) is a serious and potentially life-threatening condition. Both acute chronic conditions may alter potassium homeostasis. Our aim to describe HK incidence, clinical outcomes, associated resource use within large, integrated healthcare system. Methods: Adult patients seen at Intermountain Healthcare facilities with serum (sK) result between January 1, 2003 December 31, 2018 were retrospectively studied. Descriptive assessment of population HK, defined by...