A5015665346- Oral and Maxillofacial Pathology
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Tumors and Oncological Cases
- Head and Neck Cancer Studies
- Vascular Malformations and Hemangiomas
- Oral Health Pathology and Treatment
- Head and Neck Surgical Oncology
- Cleft Lip and Palate Research
- Microbial infections and disease research
- dental development and anomalies
- Osteomyelitis and Bone Disorders Research
- Vascular Malformations Diagnosis and Treatment
- Oral and gingival health research
- Ear and Head Tumors
- Teratomas and Epidermoid Cysts
- Histiocytic Disorders and Treatments
- Bone Tumor Diagnosis and Treatments
- Periodontal Regeneration and Treatments
- Tracheal and airway disorders
- Bone health and treatments
- Sarcoma Diagnosis and Treatment
- Inflammatory mediators and NSAID effects
- Soft tissue tumor case studies
- Vascular Tumors and Angiosarcomas
Iwate Medical University
2008-2022
Tokyo University of Agriculture and Technology
2022
Morioka University
2015
Oita University
1992-2001
Shimizu (Japan)
1993
Yokohama City University
1992
Oita Medical Center
1982-1991
Tokyo Medical and Dental University
1976-1981
Molecular mechanism underlying the invasion of oral cancer cells remains to be clarified. We previously demonstrated that transforming growth factor-β1 (TGF-β1) induces expression mesenchymal markers in human squamous cell carcinoma HSC-4 cells. Intriguingly, epithelial–mesenchymal transition-related transcription factor Slug was also significantly upregulated upon TGF-β1 stimulation. However, by which transduces TGF-β1-induced signal enhance invasiveness is poorly understood. Proteomic...
Arteriovenous malformations (AVMs) of the mandible are relatively rare and potentially life-threatening lesions. Treatment is usually difficult. This study presents a case with high-flow AVM in which most were occluded by transvenous coil embolization.Transvenous embolization using several size 57 microcoils 3 Gianturco coils was performed through right femoral vein access. The small residual superselective transarterial injection cyanoacrylate.Angiography after showed almost complete...
Background Oral lichen planus (OLP) is a T‐cell‐mediated inflammatory disease; however, its exact etiology unknown. Hyperkeratosis often observed in OLP lesions. Previous studies have revealed the localization of Mycoplasma salivarium epithelial cells oral leukoplakia with hyperkeratosis. Herein, we investigated presence M. tissue by immunohistochemistry to determine causative factor OLP. Methods Forty‐one formalin‐fixed, paraffin‐embedded samples obtained from 31 patients were examined. Ten...
Bisphosphonates are used for the management of bone metastatic disease and hypercalcemia caused by malignancy, as well treatment osteoporosis. Recently, a number patients with bisphosphonate-associated osteomyelitis osteonecrosis jaws have been reported in English-language literature. This report describes bisphosphonate-related Japan. The subjects were enrolled using questionnaires sent to 239 institutions certified training facilities Japanese Society Oral Maxillofacial Surgeons 2006....
J Oral Pathol Med (2011) 40: 227–234 Background: An in vitro cell culture system of dental epithelium is useful for the investigations cellular differentiation and function ameloblast amelogenesis regenerative therapy human tooth. However, there have been no immortalized epithelial ameloblastic-lineage lines, which proliferate indefinitely additionally produce enamel matrix proteins. Methods: We transfected two retroviral constructs telomerase reverse transcriptase (hTERT) cDNA mouse...
Background Mycoplasmas are the smallest free‐living organisms; Mycoplasma salivarium and M ycoplasma orale most common species isolated from oropharynx. Oral leukoplakia is prevalent potentially malignant disorder of oral mucosa; its etiology has not been defined. Our previous study with DNA ‐binding fluorescent dye suggested presence mycoplasmas in epithelial cells tissue. Objective aim was to detect . by immunohistochemistry. Design We produced a polyclonal antibody ( PAb ) reactive...
Abstract Funding Acknowledgements Type of funding sources: None. Background/Introduction: Congestive heart failure (CHF), the main reason for morbidity and mortality, is considered a serious consequence myocardial infarction (MI). The use left ventricular end-diastolic pressure (LVEDP) as chief indicator CHF becomes limited because possible impairment cardiac function induced aortic valve damage during its recording. Echocardiography gold standard approach to diagnose structural dysfunction....
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated systems are RNA-mediated adaptive immune that actagainst invading genetic elements such as phages or plasmids. CRISPR/Cas exist in nearly half of bacteria. Mycoplasma salivarium is a commensal species the oropharynx. The American Type Culture Collection maintains five M. strains: ATCC 14277, 23064, 23557, 29803, and 33130. genome sequence 23064 revealed it has an incomplete system. However, sequences...
Peripheral odontoma is rare, and only two cases of congenital peripheral have been reported. Congenital oral fibroma also rare. We describe a unique case developing accompanied by teratomatous in an infant. Both tumors were difficult to detect on radiography. Two small masses seen the median anterior portion palatal mucosa 9-month-old boy. The had present since birth surgically removed at age 28 months, when one grown diameter 8 mm. Histopathologic examination showed fibrous lesion tooth...
Bacteria in genus Mycoplasma spp. are the smallest and simplest form of freely replicating bacteria, with 16 species known to infect humans. In mouth, M. salivarium is most frequently identified species. parasites small genomes. Although that humans remain attached host cell surface throughout their life cycle, we have previously reported presence epithelial cells oral leukoplakia lichen planus. However, mechanism underlying pathogenicity has remained unclear. Further studies needed identify...
We studied 1809 patients with oral cancer who visited and were treated in 2002 at the 148 institutions certified as training facilities by Japanese Society of Oral Maxillofacial Surgeons, which comprise 39 dental university hospitals, 44 medical 64 general 1 unknown institution. The 1071 (59.2%) males 738 (40.8%) females (male: female ratio, 1.45: 1), had a mean age 65.2 years. tongue (40.2%) was most common site affected, followed gingiva (32.7%), buccal mucosa (10.1%), floor (9.0%). There...
Temporomandibular joint (TMJ) disorders (TMD) are usually diagnosed based on the patient's clinical findings and results of image investigations; however, understanding inflammatory process in TMJ is difficult. In addition, many disease types share common principal symptoms. Therefore, diseases early stage can be misdiagnosed with TMD. It hypothesized that cytopathologic examination lavage fluids useful interpreting TMD‐associated from a cellular aspect. The aim this study was to assess...
J Oral Pathol Med (2013) 42 : 133–139 Background: The product of the Wilms’ tumor gene, WT1 protein, is a antigen for various kinds cancer, and peptide‐based cancer immunotherapy widely anticipated as new possibility treatment. aim this study was to investigate expression from quantitative morphological perspectives in oral squamous cell carcinoma (OSCC), most widespread malignant neoplasm cavity. Methods: Six OSCC lines tissue sections 29 patients were analyzed. To detect expression,...
A 6‐week‐old male infant with lingual mass suffered from feeding difficulty and respiratory distress. Resected specimens revealed brain tissue composed of astroglia, oligodendroglia, ependyma, choroid plexus, neuronal cells, primitive cells but no other elements suggestive teratoma, therefore it was diagnosed as heterotopic the tongue. ACTA PATHOL. JPN. 1397 ‐1402, 1986.
A case of primary ameloblastic carcinoma the mandible is reported. The patient was a 15-year-old boy with complaint swelling gingiva adjacent to lower left canine. He visited our department receive further examination lesion. bone-like hard detected in area from buccal canine mucobuccal fold. On basis results biopsy, an diagnosed. After confirming absence systemic metastasis, we performed segmental mandibulectomy metal plate reconstruction under general anesthesia May 2013. diagnosis...
Paranasal sinuses and the mandible are most common sites of metastasis from renal cell carcinoma in oral maxillofacial region. Renal with maxillary gingival is rare. We report a case diagnosed after discovery swelling. The patient was 77-year-old man who presented to our department swelling left gingiva. An exophytic mass measuring 41 × 31 mm found gingiva between central incisor first premolar. Based on results biopsy imaging examinations, diagnosed. Because an abdominal aortic aneurysm...