Mohammed Lakrat

ORCID: 0000-0003-2709-5989
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Research Areas
  • Bone Tissue Engineering Materials
  • Dental Implant Techniques and Outcomes
  • Dental materials and restorations
  • Radioactive element chemistry and processing
  • Calcium Carbonate Crystallization and Inhibition
  • Electrospun Nanofibers in Biomedical Applications
  • biodegradable polymer synthesis and properties
  • Thermal and Kinetic Analysis
  • Phytochemistry and Bioactivity Studies
  • Extraction and Separation Processes
  • Endodontics and Root Canal Treatments
  • Studies on Chitinases and Chitosanases
  • Salmonella and Campylobacter epidemiology
  • Nanoplatforms for cancer theranostics
  • Advanced Cellulose Research Studies
  • Graphene and Nanomaterials Applications
  • Nanocomposite Films for Food Packaging
  • Therapeutic Uses of Natural Elements
  • Proteins in Food Systems
  • Nigella sativa pharmacological applications
  • Viral gastroenteritis research and epidemiology
  • Chemical Synthesis and Characterization
  • Advanced Drug Delivery Systems
  • Brucella: diagnosis, epidemiology, treatment
  • Pigment Synthesis and Properties

Mohamed I University
2017-2024

Premier University
2022

Mohammed V University
2022

Université Mohammed VI Polytechnique
2022

Institut des Hautes Études Bancaires et Financières
2019

Université Hassan II Mohammedia
2019

Carbonated hydroxyapatite (C-HAp) is one of the most attractive biomaterials for bone tissue engineering due to its compositional and biological similarity mineral part human bone. In present work, we have used a two-step fabrication process precipitate poorly crystalline Hydroxyapatite with nano-size particles at room temperature (20 °C) through dissolution-precipitation process. For first time, stoichiometric (S-HAp) was as precursor. The obtained C-HAp evaluated structure; chemical...

10.1016/j.matpr.2020.06.100 article EN cc-by-nc-nd Materials Today Proceedings 2020-01-01

ABSTRACT Hydrogels offer a promising solution for sustained and controlled drug delivery cell‐tissue biocompatibility. In the intervertebral disc (IVD), delivering growth factors faces challenges due to antagonistic inflammatory environment continuous mechanical stress, which can degrade biological agents may reduce their local activity. To address this, we investigated prolonged release of platelet‐derived factor isoforms BB (PDGF‐BB) AB (PDGF‐AB) by using N‐desulfated heparin...

10.1002/jbm.a.37918 article EN Journal of Biomedical Materials Research Part A 2025-05-01

is an interesting source of bioactive compounds commonly used for various therapeutic purposes. Associate its seeds extracts with biomaterials to improve their antimicrobial properties are highly demanded. This study aims investigate the encapsulation

10.3390/antibiotics11020170 article EN cc-by Antibiotics 2022-01-28

Hydroxyapatite nanoparticles (nHAp) have excellent properties, such as biocompatibility and osteoconductivity, which are critical for bone reconstruction. However, they remain inactive against pathogenic bacteria that can grow in defected tissue, their use some patients may result undesirable inflammatory reactions. Gallic acid (GA) is known its specific anti-inflammatory antibacterial properties. Coupling these characteristics with nHAp of great interest. The present study investigated the...

10.1016/j.jtemin.2022.100009 article EN cc-by-nc-nd Journal of Trace Elements and Minerals 2022-07-15

In the last decade calcium phosphate composites and other related biomaterials, were commercially used for bone substitution or allogrefts. this study, a method was developed purpose. composite hydroxyapatite (HAp) placed in cellulose structure by dissolving precipitation technique. The produced biocompatible extensively characterized means of Fourier-transform infrared spectroscopy, thermogravimetric analysis, powder X-ray diffraction, dynamic light scattering, scanning electron microscopy....

10.1080/00914037.2020.1725758 article EN International Journal of Polymeric Materials 2020-02-24

Hydroxyapatite (HAp) is a biomaterial with large number of useful applications.In this work, method for the preparation HAp at nanoscale was developed (nano-HAp).The prepared nano-HAp used in extraction methyl orange (MO) from water.The special chemical composition, crystal structure and molecular MO made occurs good efficiency.Structure confirmed by powder X-ray diffraction, Fourier transform infrared spectroscopy scanning electron microscope.Batch experiments were to evaluate tendency...

10.5004/dwt.2017.21260 article EN cc-by-nc-nd Desalination and Water Treatment 2017-08-01

Hydroxyapatite nanoparticles (nHap) with chemical and structural characteristics similar to the bone mineral are widely used for orthopaedic applications. However, conventional sintering methods applied consolidate nHap alter significantly their properties. Recently, a near-room temperature process was developed using sodium silicate solution (SS) as binder produce highly reactive composites. In this work, central composite design is employed determine best parameters elaborate nHap/SSG...

10.1080/10667857.2022.2053405 article EN Materials Technology 2022-03-29

Nanocrystalline hydroxyapatite (n-HAp), which has low crystallinity, attracted great attention due to its similarity the inorganic part of human bone. Therefore, many studies have focused on creating new formulations combining n-HAp with some biopolymers, such as chitosan, in order imitate biological bone tissue. The importance chitosan and derivatives biomedical applications grown significantly last three decades biodegradability renewable source. Besides, present excellent biocompatibility...

10.15259/pcacd.25.010 article EN Progress on Chemistry and application of Chitin and its Derivatives 2020-09-30

This study investigates, in the first part, synthesis and purification of a poorly crystalline hydroxyapatite (HAp) using natural Moroccan phosphate (Boucraa region) as raw material. Despite its successful preparation, obtained HAp was contaminated by several metallic cations (mostly Cd, Pb, Sn, Ti, Mn, Mg, Fe, Al) migrated from rocks during digestion process, inhibiting application sectors. To minimize existence these elements, dissolution-precipitation technique (DP) investigated...

10.3390/molecules29163854 article EN cc-by Molecules 2024-08-14

In a ternary system composed of aluminum phosphate, zinc oxide, and orthophosphoric acid, we have prepared microporous ceramics for orthopedic dental uses. Firstly, the with uncontrollable porosity by sintering blocs phosphate cement drawn from system. Then, based on binary consisted some porogenic additives, good homogeneous structure. second issue, preparation is made simple mixture powders. Thus, after homogenization, compaction at high temperatures, resulted developed mechanical...

10.48317/imist.prsm/morjchem-v7i4.18131 article EN 2019-10-30
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