Natalie A. Barratt
- SARS-CoV-2 and COVID-19 Research
- Animal Virus Infections Studies
- Immunotherapy and Immune Responses
University of Sheffield
2023
Abstract Pronounced immune escape by the SARS-CoV-2 Omicron variant has resulted in many individuals possessing hybrid immunity, generated through a combination of vaccination and infection. Concerns have been raised that omicron breakthrough infections triple-vaccinated result poor induction omicron-specific prior infection is associated with dampening. Taking broad comprehensive approach, we characterize mucosal blood immunity to spike non-spike antigens following BA.1/BA.2 triple...
Abstract Pronounced immune escape by the SARS-CoV-2 Omicron variant has resulted in large numbers of individuals with hybrid immunity, generated through a combination vaccination and infection. Based primarily on circulating neutralizing antibody (NAb) data, concerns have been raised that omicron breakthrough infections triple-vaccinated result poor induction omicron-specific history prior particular is associated profound dampening. Taking broader comprehensive approach, we characterized...