A5024373359- Advanced Polymer Synthesis and Characterization
- Dental materials and restorations
- Dental Research and COVID-19
- Antimicrobial agents and applications
- Covalent Organic Framework Applications
- Oral microbiology and periodontitis research
- Natural product bioactivities and synthesis
- Pharmacological Effects of Natural Compounds
- Endodontics and Root Canal Treatments
- Supramolecular Chemistry and Complexes
- Polymer composites and self-healing
- Supramolecular Self-Assembly in Materials
- Polymer Surface Interaction Studies
- Rheumatoid Arthritis Research and Therapies
- Polydiacetylene-based materials and applications
University at Buffalo, State University of New York
2020-2024
Foshan University
2024
Buffalo BioLabs
2020
State University of New York
2020
Poly(ethylene glycol) (PEG) is a highly biocompatible and water-soluble polymer that widely utilized for biomedical applications. Unfortunately, the immunogenicity antigenicity of PEG severely restrict efficacy pegylated therapeutics. As emerging alternatives, biodegradable zwitterionic polymers (ZPs) have attracted significant interest in recent years. Biodegradable ZPs generally are not only immunologically inert, but also possess range favorable biomedically relevant properties, without...
Dynamic covalent polymeric networks (DCPNs) with hindered urea bonds and free thiol groups were prepared. Due to the catalyst-free conversion of dynamic thiourethane bonds, these materials showed enhanced mechanical properties along time or triggered by elevated temperature, exhibited excellent self-healing performance.
This work reports on polymer-antibiotic conjugates (PACs) as additives to resin-based restorative dental materials a new strategy convey sustained antibacterial character these materials. Such performance is expected improve their longevity in the oral cavity. Using previously reported ciprofloxacin (Cip)-based PAC control, penicillin V (PV)-based was investigated. The monomer-antibiotic conjugate (MAC) containing methacrylate monomer group and PV moiety prepared via nucleophilic...
Background: The Juan-Bi decoction (JBD) is a classic traditional Chinese medicines (TCMs) prescription for the treatment of rheumatoid arthritis (RA). However, active compounds JBD in RA remain unclear. Aim: aim this study to screen effective using systems pharmacology and experimental approaches. Method: Botanical drugs were acquired from multiple public TCM databases. All initially screened absorption, distribution, metabolism, excretion, toxicity (ADMET) physicochemical properties, then...