- Aquaculture disease management and microbiota
- Vibrio bacteria research studies
- Advanced biosensing and bioanalysis techniques
- Invertebrate Immune Response Mechanisms
- Viral gastroenteritis research and epidemiology
- Cancer Research and Treatments
- Immunotherapy and Immune Responses
- Fungal Biology and Applications
- Virus-based gene therapy research
- Bee Products Chemical Analysis
- Phytochemicals and Antioxidant Activities
- Immune Response and Inflammation
- Glycosylation and Glycoproteins Research
- Bacteriophages and microbial interactions
- Fibroblast Growth Factor Research
- Viral Infections and Immunology Research
- Escherichia coli research studies
- Biosensors and Analytical Detection
- Electrospun Nanofibers in Biomedical Applications
- Polysaccharides Composition and Applications
- Bacterial Genetics and Biotechnology
- Advanced Biosensing Techniques and Applications
- Prion Diseases and Protein Misfolding
- Adipose Tissue and Metabolism
- Wound Healing and Treatments
Ho Chi Minh City University of Science
2017-2025
Vietnam National University Ho Chi Minh City
2016-2025
Zero to Three
2022
University of Würzburg
2010
The Type V secretion system, or "autotransporter", is a system that enables bacteria to directly export proteins from the cell interior extracellular membrane. mCherry second-generation monomeric red fluorescent protein has an improvement in photostability compared first generation of RFP. In this research, we conducted fusion mRFP into C-terminal domain EhaA - translocation autotransporter transport investigate expression on surface
Recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) is a glycoprotein that has been approved by the FDA for treatment of neutropenia and leukemia in combination with chemotherapies. hGM-CSF produced industrially using baker's yeast, Saccharomyces cerevisiae, large-scale fermentation. The methylotrophic Pichia pastoris, emerged as an alternative host cell system due to its shorter less immunogenic glycosylation pattern together higher density growth secreted protein...
Background: Hand, Foot, and Mouth disease is an acute infectious caused by a group of enteroviruses, including Coxsackievirus A16 Enterovirus 71. EV-A71-causing can give rise to severe complications in children, leading meningitis, encephalitis, even death. A potential approach prevent the virus spread inhibiting invasion EV-A71 into target cells, thereby helping not only community but also lessen risk outbreaks. cell’s receptor, human scavenger receptor class B member 2, SCARB2, was used as...
Acute hepatopancreatic necrosis disease (AHPND) is a contagious in shrimp with extremely high mortality rate, causing an estimated $23.6 billion loss to the global industry during 2009–2016. A binary toxin, PirAB, causative agent, which encoded by pirABvp genes on virulent plasmid typically found Vibrio parahaemolyticus. Here, seventeen strains of V. parahaemolyticus were isolated from Mekong Delta Vietnam, 15 harboured identical genes. The remaining two strains, PCR-negative for pirAB, and...
Measles virus (MV)-infected DC fail to promote T-cell expansion, and this could explain important aspects of measles immunosuppression. The efficiency the immune synapse (IS) is determined by formation stable, stimulatory conjugates involving a spatially timely controlled architecture. PlexinA1 (plexA1) its co-receptor neuropilin (NP-1) have been implicated in IS efficiency, while their repulsive ligand, SEMA3A, likely acts terminating activation. Conjugates MV-infected T cells are unstable...
Astaxanthin (AX) is a natural compound that regulates lipid metabolism in the liver, specifically reducing hepatosteatosis. To increment Non-Alcoholic Fatty Liver Diseases (NAFLD) ratio and its burdens, prevention/treatment should address world health problem. This study aimed to evaluate ability of AX prolonged effects on physiology mice fed high-fat diet. Mice with diet (HFD) (n=12) were orally given at dosage 30 mg/kg body weight/day for 16 weeks, followed by eight weeks termination,...
Summary Here, five selected Vietnam Ganoderma lucidum varieties were first prepared and examined for total polyphenol content (TPC) antioxidant activities (including DPPH, FRAP tyrosinase inhibition). All the extracts exhibited significant bioactivities, which could be attributed to their large TPC values with Pearson statistical coefficients r ~ 0.8 ( P < 0.10). Ethanol extract of Korean lingzhi (E‐KR), largest bioactive one, was identified 16 compounds using FT‐IR HPLC‐MS, including...
Fibroblast growth factor 2 (FGF-2) is a multifunctional protein that has major roles in wound healing, tissue repair, and regeneration. This therapeutic widely used for burn treatment because it can stimulate cell proliferation differentiation, angiogenesis, extracellular matrix remodeling. In this study, we developed simple method using controlled heated brass rod to create homogenous third-degree murine model evaluated the recombinant human FGF-2 (rhFGF-2). The results indicated area was...
Acute hepatopancreatic necrosis disease (AHPND) is caused by toxin-producing strains of Vibrio parahaemolyticus which contain deadly binary toxins PirA
Acute Hepatopancreatic Necrosis Disease (AHPND) is a newly emerging shrimp disease with mortality up to 100 percent caused by Vibrio parahaemolyticus which carries plasmid encoding for two toxins, ToxA and ToxB. In 2013, the Global Aquaculture Alliance (GAA) estimated farming decline in Asia accounted 1-billion US dollar lost. Currently, diagnosis using PCR method does not meet demand of situ detection, based on antigen-antibody interaction, has been developed yet. this present study, we...
Coffee (Coffea robusta) flower honey is one of the highest-yielding kinds in Vietnam. Nevertheless, there little research on antifungal activity associated with this type honey. Therefore, study was conducted to investigate against C. albicans Vietnamese coffee monofloral and its potential effects biofilm formation. This using broth microdilution method. The results showed that resistant Candida strain minimum inhibitory concentration (MIC) fungicidal (MFC) values 50% 70% (w/v),...