- Synthesis and biological activity
- Photosynthetic Processes and Mechanisms
- Free Radicals and Antioxidants
- Synthesis and Biological Evaluation
- Fungal Plant Pathogen Control
- Nanoparticles: synthesis and applications
- Plant Stress Responses and Tolerance
- Heavy Metals in Plants
- Heavy metals in environment
- Plant Micronutrient Interactions and Effects
- Algal biology and biofuel production
- Synthesis and Reactions of Organic Compounds
- Porphyrin and Phthalocyanine Chemistry
- Graphene and Nanomaterials Applications
- Allelopathy and phytotoxic interactions
- Plant-Microbe Interactions and Immunity
- Bioactive Compounds and Antitumor Agents
- Quinazolinone synthesis and applications
- Light effects on plants
- Photochemistry and Electron Transfer Studies
- Synthesis of Organic Compounds
- Phenothiazines and Benzothiazines Synthesis and Activities
- Analytical Chemistry and Chromatography
- Spectroscopy and Quantum Chemical Studies
- Metal complexes synthesis and properties
Central European Institute of Technology
2025
Central European Institute of Technology – Masaryk University
2025
Comenius University Bratislava
2015-2024
Institute of Chemistry of the Slovak Academy of Sciences
2015-2024
Vysoká škola manažmentu, City University of Seattle
2019
Charles University
1999-2006
Abstract Nanoagrochemicals, such as nanopesticides, nanofertilizers or plant growth stimulating nanosystems, were primarily designed to increase solubility, enhance bioavailability, targeted delivery, controlled release and/or protection against degradation resulting in the reduced amount of applied active ingredients and finally a decrease dose-dependent toxicity/burden. This paper is comprehensive up-to-date review related preparation biological activity nanoformulations enabling gradual...
Microtubule associated protein 2 (MAP2) interacts with the regulatory 14‐3‐3ζ in a cAMP‐dependent kinase (PKA) phosphorylation dependent manner. Using selective phosphorylation, calorimetry, nuclear magnetic resonance, chemical crosslinking, and X‐ray crystallography, we characterized interactions of various binding regions MAP2c. Although PKA increases affinity MAP2c for proline rich region C‐terminal domain, unphosphorylated also binds dimeric via its microtubule domain variable central...
In this study, series of ring-substituted 2-styrylquinazolin-4(3H)-one and 4-chloro-2-styrylquinazoline derivatives were prepared. The syntheses the discussed compounds are presented. analyzed by RP-HPLC to determine lipophilicity. They tested for their inhibitory activity on photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. Primary vitro screening synthesized was also performed against four mycobacterial strains eight fungal strains. Several showed...
Abstract Metal nanoparticles (MNPs) belong mostly to the engineered type of and have not only unique physical chemical properties but also different biological actions. In recent years, noble MNPs their nano-sized agglomerates (collectively referred as or particles in subsequent sections) been subjects much focused research due electronic, optical, mechanical, magnetic that can be significantly from those bulk materials. To enhance use, it is important understand generation, transport,...
Medicinal and aromatic plants have been used by mankind since ancient times. This is primarily due to their healing effects associated with specific secondary metabolites (some of which are also as drugs in modern medicine), or structures, served a basis for the development new effective synthetic drugs. One way increase production these use nanoparticles that act elicitors. However, depending on particle size, composition, concentration, route application, may several other benefits...
In the study, a series of twelve ring-substituted 4-hydroxy-1H-quinolin-2-one derivatives were prepared. The procedures for synthesis compounds are presented. analyzed using RP-HPLC to determine lipophilicity and tested their photosynthesis-inhibiting activity spinach (Spinacia oleracea L.) chloroplasts. All synthesized also evaluated antifungal in vitro screening with eight fungal strains. For all compounds, relationships between chemical structure studied discussed, as well...
In this study, a series of thirty-five substituted quinoline-2-carboxamides and thirty-three naphthalene-2-carboxamides were prepared characterized. They tested for their activity related to the inhibition photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. Primary vitro screening synthesized compounds was also performed against four mycobacterial species. N-Cycloheptylquinoline-2-carboxamide, N-cyclohexylquinoline-2-carboxamide...
In this study, a series of twenty-two ring-substituted 3-hydroxy-N-phenylnaphthalene-2-carboxanilides were prepared and characterized. The compounds tested for their activity related to inhibition photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. Primary vitro screening the synthesized was also performed against four Staphylococcus strains two mycobacterial species. 3-Hydroxy-N-(2-methoxyphenyl)naphthalene-2-carboxamide showed high biological (MIC = 55.0...
Condensation of the corresponding chlorides some substituted pyrazine-2-carboxylic acids (pyrazine-2-carboxylic acid, 6-chloropyrazine-2-carboxylic 5-tert-butylpyrazine-2-carboxylic acid or 5-tert-butyl-6-chloropyrazine-2-carboxylic acid) withvarious ring-substituted aminothiazoles anilines yielded a series amides. Thesyntheses, analytical and spectroscopic data thirty newly prepared compounds arepresented. Structure-activity relationships between chemical structures anti-mycobacterial,...